ChemicalBook > CAS DataBase List > Actarit

Actarit

Product Name
Actarit
CAS No.
18699-02-0
Chemical Name
Actarit
Synonyms
Orcl;ms932;Mover;FAM79A;TPRG1L;ACTARIT;Ake him;Mirabegron M9;Protein FAM79A;AKETALI (ACTARIT)
CBNumber
CB7732469
Molecular Formula
C10H11NO3
Formula Weight
193.2
MOL File
18699-02-0.mol
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Actarit Property

Melting point:
173-175°C
Boiling point:
449.1±28.0 °C(Predicted)
Density 
1.288±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO, Ethanol, Methanol
form 
Solid
pka
4.34±0.10(Predicted)
color 
White to Off-White
Merck 
14,133
CAS DataBase Reference
18699-02-0(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
RTECS 
CY1542000
HS Code 
29163990
Toxicity
LD50 in male, female mice, male, female rats (mg/kg): 1.06, 1.30, 1.95, 2.03 i.p.; 5.68, 5.48, 5.48, 6.12 s.c.; 15.3, 14.7, 14.8, 15.4 orally (Toshida)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2793
Product name
Actarit
Purity
>97.0%(GC)
Packaging
100mg
Price
$28
Updated
2024/03/01
Cayman Chemical
Product number
20852
Product name
Actarit
Purity
≥98%
Packaging
5g
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
20852
Product name
Actarit
Purity
≥98%
Packaging
10g
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
20852
Product name
Actarit
Purity
≥98%
Packaging
25g
Price
$185
Updated
2024/03/01
Cayman Chemical
Product number
20852
Product name
Actarit
Purity
≥98%
Packaging
50g
Price
$302
Updated
2024/03/01
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Actarit Chemical Properties,Usage,Production

Description

Actarit is an orally administered disease-modifying antirheumatic drug launched in Japan. Although its structure resembles that of non-steroidal anti-inflammatory drugs, it has no effect on experimental acute inflammation and has no analgesic or antipyretic effects. Its preventative and therapeutic effects on adjuvant arthritis are mediated via modulation of production and serum level of interleukin-2 which enhances production of suppressor T-cells to the immune system, thereby, preventing development of articular lesions.

Chemical Properties

Crystalline Solid

Originator

Nippon Shlnyaku;Mltaublshl Kasel (Japan)

Uses

Antiarthritic

Uses

Chronic rheumatoid arthritis

Definition

ChEBI: Actarit is an anilide and a member of acetamides.

brand name

Orcl; Mover

Purification Methods

Crystallise the acid from MeOH/Me2CO, aqueous EtOH or H2O. The amide has m 231o (from 50% aqueous EtOH). [Gabriel Chem Ber 15 841 1882, Cerecedo et al. J Biol Chem 42 238 1924, Tramontano et al. J Am Chem Soc 110 2282 1988, Beilstein 14 II 281.]

Actarit Preparation Products And Raw materials

Raw materials

Preparation Products

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Actarit Suppliers

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View Lastest Price from Actarit manufacturers

Hebei Duling International Trade Co. LTD
Product
Actarit 18699-02-0
Price
US $56.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 tons
Release date
2023-04-18
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Actarit 18699-02-0
Price
US $13.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000tons
Release date
2021-12-28
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
Actarit 18699-02-0
Price
US $16.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
69KG
Release date
2022-01-10

18699-02-0, ActaritRelated Search:

Acetaminophen 4-Hydroxyphenylacetic acid 4-Methoxyphenylacetic acid 2-Hydroxyphenylacetic acid ALPHA-METHYL-P-[1-OXO-2-ISOINDOLINYL]-BENZENEACETIC ACID dexindoprofen 7-Diethylamino-3-(4'-maleimidylphenyl)-4- methylcoumarin Phenylacetic acid Indobufen 4-Aminophenylacetic acid PKSI 527 7-Diethylamino-3-[4-(iodoacetamido)phenyl]-4-methylcoumarin (4-[(3-METHYL-FURAN-2-CARBONYL)-AMINO]-PHENYL)-ACETIC ACID Actarit-d4 Desacetyl Actarit-d4 Actarit ASISCHEM D13241 N-(3-METHYL-4-(2-OXO-2H-CHROMEN-3-YL)PHENYL)-2-(O-TOLYLOXY)ACETAMIDE

  • 4-(acetylamino)-benzeneacetic acid
  • [4-(ACETYLAMINO)PHENYL]ACETIC ACID
  • (p-acetamidophenyl)-aceticaci
  • (p-acetamidophenyl)aceticacid
  • 4-(acetylamino)-benzeneaceticaci
  • 4-n-acetylaminophenylaceticacid
  • ms932
  • RARECHEM AL BO 1520
  • 4-ACETAMIDO-PHENYLACETIC ACID
  • ACTARIT
  • Mover
  • Orcl
  • ANTI-TPRGL (N-TERM) antibody produced in rabbit
  • FAM79A
  • Mossy fiber terminal-associated vertebrate-specific presynaptic protein
  • Protein FAM79A
  • TPRG1L
  • Tumor protein p63-regulated gene 1-like protein
  • Mirabegron M9 (YM-340790)
  • 4-Acetamido-phenylacetic acid ,97%
  • O-(Carboxymethyl)paracetamol
  • p-Acetylaminophenylacetic acid
  • N-acetyl-4-aMinophenyl-acetic acid
  • ActaritIn-houseStandard
  • AKETALI (ACTARIT)
  • Mirabegron M9
  • Benzeneaceticacid, 4-(acetylamino)-
  • 2-(4-acetamidocyclohexyl)acetate
  • Actarit USP/EP/BP
  • Mirabegron-metabolite M9
  • Ake him
  • 2-(4-acetamidophenyl)aceticaci
  • 18699-02-0
  • Aromatic Phenylacetic Acids and Derivatives
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals