Actarit
- Product Name
- Actarit
- CAS No.
- 18699-02-0
- Chemical Name
- Actarit
- Synonyms
- Orcl;ms932;Mover;FAM79A;TPRG1L;ACTARIT;Ake him;Mirabegron M9;Protein FAM79A;AKETALI (ACTARIT)
- CBNumber
- CB7732469
- Molecular Formula
- C10H11NO3
- Formula Weight
- 193.2
- MOL File
- 18699-02-0.mol
Actarit Property
- Melting point:
- 173-175°C
- Boiling point:
- 449.1±28.0 °C(Predicted)
- Density
- 1.288±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO, Ethanol, Methanol
- form
- Solid
- pka
- 4.34±0.10(Predicted)
- color
- White to Off-White
- Merck
- 14,133
- CAS DataBase Reference
- 18699-02-0(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- RTECS
- CY1542000
- HS Code
- 29163990
- Toxicity
- LD50 in male, female mice, male, female rats (mg/kg): 1.06, 1.30, 1.95, 2.03 i.p.; 5.68, 5.48, 5.48, 6.12 s.c.; 15.3, 14.7, 14.8, 15.4 orally (Toshida)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A2793
- Product name
- Actarit
- Purity
- >97.0%(GC)
- Packaging
- 100mg
- Price
- $28
- Updated
- 2024/03/01
- Product number
- 20852
- Product name
- Actarit
- Purity
- ≥98%
- Packaging
- 5g
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 20852
- Product name
- Actarit
- Purity
- ≥98%
- Packaging
- 10g
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 20852
- Product name
- Actarit
- Purity
- ≥98%
- Packaging
- 25g
- Price
- $185
- Updated
- 2024/03/01
- Product number
- 20852
- Product name
- Actarit
- Purity
- ≥98%
- Packaging
- 50g
- Price
- $302
- Updated
- 2024/03/01
Actarit Chemical Properties,Usage,Production
Description
Actarit is an orally administered disease-modifying antirheumatic drug launched in Japan. Although its structure resembles that of non-steroidal anti-inflammatory drugs, it has no effect on experimental acute inflammation and has no analgesic or antipyretic effects. Its preventative and therapeutic effects on adjuvant arthritis are mediated via modulation of production and serum level of interleukin-2 which enhances production of suppressor T-cells to the immune system, thereby, preventing development of articular lesions.
Chemical Properties
Crystalline Solid
Originator
Nippon Shlnyaku;Mltaublshl Kasel (Japan)
Uses
Antiarthritic
Uses
Chronic rheumatoid arthritis
Definition
ChEBI: Actarit is an anilide and a member of acetamides.
brand name
Orcl; Mover
Purification Methods
Crystallise the acid from MeOH/Me2CO, aqueous EtOH or H2O. The amide has m 231o (from 50% aqueous EtOH). [Gabriel Chem Ber 15 841 1882, Cerecedo et al. J Biol Chem 42 238 1924, Tramontano et al. J Am Chem Soc 110 2282 1988, Beilstein 14 II 281.]
Actarit Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from Actarit manufacturers
- Product
- Actarit 18699-02-0
- Price
- US $56.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000 tons
- Release date
- 2023-04-18
- Product
- Actarit 18699-02-0
- Price
- US $13.50/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000tons
- Release date
- 2021-12-28
- Product
- Actarit 18699-02-0
- Price
- US $16.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 69KG
- Release date
- 2022-01-10