5-Hydroxy-2-nitrobenzoic acid
- Product Name
- 5-Hydroxy-2-nitrobenzoic acid
- CAS No.
- 610-37-7
- Chemical Name
- 5-Hydroxy-2-nitrobenzoic acid
- Synonyms
- RARECHEM AL BE 0679;3-carboxy-4-nitrophenol;5-Hydroxy-2-nitrobenzoic;5-hydroxy-2-nitro-benzoicaci;5-HYDROXY-2-NITROBENZOIC ACID;2-Nitro-5-hydroxybenzoic acid;3-Hydroxy-6-nitro benzoic acid;5-Hydroxy-2-nitrobenzoicAcid>Benzoic acid, 5-hydroxy-2-nitro-;5-Hydroxy-2-nitrobenzoic acid, tech
- CBNumber
- CB7736391
- Molecular Formula
- C7H5NO5
- Formula Weight
- 183.12
- MOL File
- 610-37-7.mol
5-Hydroxy-2-nitrobenzoic acid Property
- Melting point:
- 170-171°C
- Boiling point:
- 455.0±40.0 °C(Predicted)
- Density
- 1.631
- RTECS
- DH2528250
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 2.06±0.25(Predicted)
- color
- White to Yellow to Green
- CAS DataBase Reference
- 610-37-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H1321
- Product name
- 5-Hydroxy-2-nitrobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $60
- Updated
- 2025/07/31
- Product number
- H1321
- Product name
- 5-Hydroxy-2-nitrobenzoic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $176
- Updated
- 2025/07/31
- Product number
- H950848
- Product name
- 5-Hydroxy-2-nitrobenzoic Acid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR27506
- Product name
- 5-Hydroxy-2-nitrobenzoic Acid
- Packaging
- 1g
- Price
- $16
- Updated
- 2021/12/16
- Product number
- 4654-1-V3
- Product name
- 5-Hydroxy-2-nitrobenzoic acid
- Packaging
- 1g
- Price
- $18
- Updated
- 2021/12/16
5-Hydroxy-2-nitrobenzoic acid Chemical Properties,Usage,Production
Uses
5-Hydroxy-2-nitrobenzoic acid inhibits the activity of wild type-bovine low Mr protein tyrosine phosphatase. The inhibition constant has been evaluated.
Synthesis
2516-95-2
610-37-7
General procedure for the synthesis of 2-nitro-5-hydroxybenzoic acid from 5-chloro-2-nitrobenzoic acid: 5-chloro-2-nitrobenzoic acid (32.00 g, 0.159 mol) was dissolved in 15% aqueous sodium hydroxide solution and reacted at reflux under nitrogen protection for 72 hours. After completion of the reaction, the pH of the reaction solution was adjusted to 1.0 with dilute hydrochloric acid and then extracted with ethyl acetate. The ethyl acetate extracts were combined and dried with anhydrous sodium sulfate. The solvent was removed by distillation under reduced pressure to give 28.05 g of 2-nitro-5-hydroxybenzoic acid in 96.5% yield.
References
[1] Chemistry - A European Journal, 2013, vol. 19, # 43, p. 14654 - 14664
[2] Patent: CN106478548, 2017, A. Location in patent: Paragraph 0019-0020; 0035-0036; 0051-0052; 0067-0068
[3] Patent: US2017/158680, 2017, A1. Location in patent: Paragraph 0330; 0331; 0332
[4] Patent: WO2003/97641, 2003, A2. Location in patent: Page/Page column 63
[5] Patent: US4348396, 1982, A
5-Hydroxy-2-nitrobenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-Hydroxy-2-nitrobenzoic acid manufacturers
- Product
- 5-Hydroxy-2-nitrobenzoic acid 610-37-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.5%
- Supply Ability
- 100 tons
- Release date
- 2022-02-21
- Product
- 5-Hydroxy-2-nitrobenzoic acid 610-37-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 150KG
- Release date
- 2019-07-05