2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE
- Product Name
- 2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE
- CAS No.
- 36082-45-8
- Chemical Name
- 2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE
- Synonyms
- 5-bromo-4-methoxypyrimidin-2-amine;2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE;2-Pyrimidinamine, 5-bromo-4-methoxy-;5-bromo-4-methoxypyrimidine-2-ylamine;Pyrimidine, 2-amino-5-bromo-4-methoxy-;2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE ISO 9001：2015 REACH
- CBNumber
- CB7739963
- Molecular Formula
- C5H6BrN3O
- Formula Weight
- 204.02
- MOL File
- 36082-45-8.mol
2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE Property
- Melting point:
- 118℃
- Boiling point:
- 364.8±45.0 °C(Predicted)
- Density
- 1.723
- storage temp.
- 2-8°C(protect from light)
- pka
- 3.82±0.10(Predicted)
- Appearance
- Off-white to light yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H317May cause an allergic skin reaction
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A594545
- Product name
- 2-Amino-5-bromo-4-methoxypyrimidine
- Packaging
- 500mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- FB139414
- Product name
- 5-Bromo-4-methoxypyrimidin-2-amine
- Packaging
- 2g
- Price
- $85
- Updated
- 2021/12/16
- Product number
- W5757
- Product name
- 2-Amino-5-bromo-4-methoxypyrimidine
- Packaging
- 1g
- Price
- $122
- Updated
- 2021/12/16
- Product number
- FB139414
- Product name
- 5-Bromo-4-methoxypyrimidin-2-amine
- Packaging
- 5G
- Price
- $170
- Updated
- 2021/12/16
- Product number
- COR0001620
- Product name
- 2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $199.5
- Updated
- 2021/12/16
2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE Chemical Properties,Usage,Production
Synthesis
155-90-8
36082-45-8
General procedure for the synthesis of 2-amino-5-bromo-4-methoxypyrimidine from 2-amino-4-methoxypyrimidine: Method 14; Synthesis of 5-bromo-4-methoxypyrimidin-2-ylamine; To a solution of 4-methoxypyrimidin-2-ylamine (1.84 g, 14.7 mmol) in chloroform (600 mL) was added N-bromosuccinimide (2.62 g, 14.7 mmol). The reaction mixture was stirred under light-avoiding conditions for 5 h. The reaction solution was transferred to a mixture of dichloromethane (200 mL) and 1N sodium hydroxide solution (100 mL). After thorough mixing, the organic and aqueous phases were separated, and the organic phase was washed with saturated sodium chloride solution (100 mL), dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford 2.88 g (96% yield) of the target compound 5-bromo-4-methoxypyrimidin-2-ylamine.LCMS (m/z): 204/206 (MH+).1H NMR (CDCl3): δ 8.10 ( s, 1H), 4.93 (bs, 2H), 3.96 (s, 3H).
References
[1] Patent: WO2008/98058, 2008, A1. Location in patent: Page/Page column 66
[2] Patent: WO2007/84786, 2007, A1. Location in patent: Page/Page column 99-100
[3] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 10, p. 774 - 779
[4] Patent: WO2009/93981, 2009, A1. Location in patent: Page/Page column 104-105
[5] Journal of the American Chemical Society, 1946, vol. 68, p. 1039,1040, 1044
2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE manufacturers
- Product
- 2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE 36082-45-8
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-12-01
- Product
- 2-AMINO-5-BROMO-4-METHOXYPYRIMIDINE 36082-45-8
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 724
- Release date
- 2019-09-01