ChemicalBook > CAS DataBase List > 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID

1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID

Product Name
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID
CAS No.
149676-40-4
Chemical Name
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID
Synonyms
EU-5306;RB-1589;PERFLOXACINE;PEFLOXACIN METHANESULFONATE;Pefloxacin Mesylate dihydra;PEFLOXACIN MESYLATE DIHYDRATE;Pefloxacin (mesylate hydrate);PEFLOXACINE MESYLATE DIHYDRATE;Pefloxacin mesylate dihydrdate;Pefloxacin dihydrate mesylate
CBNumber
CB7748671
Molecular Formula
C18H28FN3O8S
Formula Weight
465.49
MOL File
149676-40-4.mol
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1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Property

Melting point:
271°C
Boiling point:
529℃
Flash point:
>110°(230°F)
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: soluble50mg/mL
form 
powder
Water Solubility 
Freely soluble in water
Sensitive 
Light Sensitive
CAS DataBase Reference
149676-40-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36
Safety Statements 
26
WGK Germany 
3
RTECS 
VB2002200
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P0309000
Product name
Pefloxacin mesilate dihydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
200 mg
Price
$156
Updated
2025/07/31
Sigma-Aldrich
Product number
P0106
Product name
Pefloxacin mesylate dihydrate
Packaging
10g
Price
$76.2
Updated
2025/07/31
Sigma-Aldrich
Product number
P0309000
Product name
Pefloxacin mesilate dihydrate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
p0309000
Price
$153
Updated
2024/03/01
TCI Chemical
Product number
P3024
Product name
Pefloxacine Mesylate Dihydrate
Packaging
5G
Price
$130
Updated
2025/07/31
Cayman Chemical
Product number
29103
Product name
Pefloxacin (mesylate hydrate)
Packaging
10g
Price
$37
Updated
2024/03/01
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1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

antifungal, calmodulin antagonist

Uses

Pefloxacin Mesylate Dihydrate is an analog of norfloxacin that inhibits topoisomerase.

Biological Activity

Pefloxacin inhibits the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited . Pefloxacin is an analog of norfloxacin.

IC 50

Quinolone

1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID Suppliers

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View Lastest Price from 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID manufacturers

Dideu Industries Group Limited
Product
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID 149676-40-4
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-07-19
Career Henan Chemical Co
Product
1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID 149676-40-4
Price
US $2.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2018-12-24

149676-40-4, 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACIDRelated Search:


  • RB-1589
  • PERFLOXACINE
  • PEFLOXACINE MESYLATE DIHYDRATE
  • PEFLOXACINE METHANSULFONATE DIHYDRATE
  • PEFLOXACIN MESYLATE DIHYDRATE
  • PEFLOXACIN METHANESULFONATE
  • PEFLOXACIN METHANE SULFONATE DIHYDRATE
  • EU-5306
  • Pefloxacinium mesylate dihydrate
  • 1-ETHYL-6-FLUORO-1,4-DIHYDRO-7-(4-METHYL-1-PIPERAZINYL-4-OXO-3-QUINOLINE CARBOXYLIC ACID) METHANE SULPHONATE DIHYDRATE
  • Pefloxacin dihydrate mesylate
  • Pefloxacine monomethanesulfonate dihydrate, Pefloxacinium methanesulfonate dihydrate, 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate
  • /1-ethyl-6-fluoro-7-(4-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid coMpound with Methanesulfonic acid (1:1
  • 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-Methyl-1-piperazinyl)-4-oxo-, Methanesulfonate, hydrate (1:1:2)
  • Pefloxacin Mesylate dihydra
  • 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate
  • Pefloxacine monomethanesulfonate dihydrate
  • Pefloxacinium methanesulfonate dihydrate
  • Pefloxacin mesylate`Pefloxacin mesylate dihydrate
  • 1-ETHYL-6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-4-OXO-QUINOLINE-3-CARBOXYLIC ACID USP/EP/BP
  • 1-Ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid mesylate dihydrate
  • Pefloxacin mesylate dihydrdate
  • Pefloxacin dihydrate methanesulfonate
  • 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-Quinolinecarboxylic acid methanesulfonate hydrate (1:1:2)
  • Pefloxacin (mesylate hydrate)
  • /1-Ethyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinolin-3-carboxylic acid compound with methanesulfonic acid (1:1
  • 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid compound with methanesulfonic acid (1:1) hydrate
  • Pefloxacin Mesylate Dihydrate, 10 mM in DMSO
  • Pefloxacin for system suitability CRS
  • 1-Ethyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid compound with methanesulfonic acid hydrate
  • 149676-40-4
  • C17H20FN3O3x2H2O
  • C17H20FN3O3x2022CH4O3Sx20222H2O
  • C18H24FN3O6S2H2O
  • C18H24FN3O6S
  • C17H20FN3O3CH4O3S2H2O
  • C18H28FN3O8S
  • MYCOSPOR