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QUAZINONE

Product Name
QUAZINONE
CAS No.
70018-51-8
Chemical Name
QUAZINONE
Synonyms
Posicor;R 13-6438;QUAZINONE;Quazinona;Quazinonum;RO 13-6438;Unii-D1Q7F6C2fp;Quazinonum [latin];Quazinona [spanish];Quazinone (Ro 13-6438)
CBNumber
CB7751165
Molecular Formula
C11H10ClN3O
Formula Weight
235.67
MOL File
70018-51-8.mol
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QUAZINONE Property

storage temp. 
RT
solubility 
ethanol: soluble1mg/mL
form 
White to off-white solid.
color 
white
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
29151
Product name
Quazinone
Packaging
5mg
Price
$73
Updated
2024/03/01
Cayman Chemical
Product number
29151
Product name
Quazinone
Packaging
10mg
Price
$104
Updated
2024/03/01
Cayman Chemical
Product number
29151
Product name
Quazinone
Packaging
25mg
Price
$234
Updated
2024/03/01
TRC
Product number
Q509453
Product name
Quazinone(Ro13-6438)
Packaging
25mg
Price
$145
Updated
2021/12/16
TRC
Product number
Q509453
Product name
Quazinone(Ro13-6438)
Packaging
10mg
Price
$75
Updated
2021/12/16
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QUAZINONE Chemical Properties,Usage,Production

Description

Ro 13-6438 (70018-51-8) is a selective inhibitor of phosphodiesterase III (PDE III, IC50 = 0.6 μM).

Uses

Cardiotonic.

Uses

Quazinone (Ro 13-6438) is a phosphodiesterase inhibitor and novel cardiotonic agent with vasodilating properties.

References

1) Eigenmann et al. (1984) Cardiovascular profile of Ro 13-6438, a novel positive inotropic agent with vasodilating properties; J. Cardiovasc. Pharmacol., 6 511 2) Holck et al. (1984) Studies on the mechanism of positive inotropic activity of Ro 13-6438, a structurally novel cardiotonic agent with vasodilating properties; J. Cardiovasc. Pharmacol. 6 520

QUAZINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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QUAZINONE Suppliers

Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9806
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
Advantage
58
Hubei Nordina Biotechnology Co., Ltd.
Tel
19371278702
Fax
18162687220
Email
nuodinashengwu@163.com
Country
China
ProdList
971
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Suzhou Zhixin Biotechnology Co., Ltd.
Tel
0512-65118909 15162312715
Email
sales@szzxbio.com
Country
China
ProdList
3004
Advantage
58
Hubei huizepu Pharmaceutical Technology Co., Ltd
Tel
023-19371278 19371278702
Email
n13164103386@163.com
Country
China
ProdList
3277
Advantage
58
Tel
4008-099-669
Email
23419001name@qq.com
Country
CHINA
ProdList
70071
Advantage
58

70018-51-8, QUAZINONERelated Search:


  • QUAZINONE
  • R 13-6438
  • RO 13-6438
  • (3R)-6-Chloro-1,5-dihydro-3-methylimidazo[2,1-b]quinazolin-2(3H)-one
  • Posicor
  • Imidazo(2,1-B)quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-, (R)-
  • Quazinona
  • Quazinona [spanish]
  • Quazinonum
  • Quazinonum [latin]
  • Unii-D1Q7F6C2fp
  • IMidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-Methyl-, (3R)-
  • Quazinone (Ro 13-6438)
  • Ro 13-6438 (Quazinone)
  • 70018-51-8
  • G Proteins and Cyclic Nucleotides
  • Cyclic Nucleotide Metabolism
  • Phosphodiesterase Inhibitors
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience