QUAZINONE

Product Name: QUAZINONE
CAS No.: 70018-51-8
Chemical Name: QUAZINONE
Synonyms: Posicor;R 13-6438;QUAZINONE;Quazinona;Quazinonum;RO 13-6438;Unii-D1Q7F6C2fp;Quazinonum [latin];Quazinona [spanish];Quazinone (Ro 13-6438)
CBNumber: CB7751165
Molecular Formula: C11H10ClN3O
Formula Weight: 235.67
MOL File: 70018-51-8.mol

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QUAZINONE Property

storage temp.: RT
solubility: ethanol: soluble1mg/mL
form: White to off-white solid.
color: white
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29151
Product name: Quazinone
Packaging: 5mg
Price: $73
Updated: 2024/03/01

Cayman Chemical

Product number: 29151
Product name: Quazinone
Packaging: 10mg
Price: $104
Updated: 2024/03/01

Cayman Chemical

Product number: 29151
Product name: Quazinone
Packaging: 25mg
Price: $234
Updated: 2024/03/01

TRC

Product number: Q509453
Product name: Quazinone(Ro13-6438)
Packaging: 25mg
Price: $145
Updated: 2021/12/16

TRC

Product number: Q509453
Product name: Quazinone(Ro13-6438)
Packaging: 10mg
Price: $75
Updated: 2021/12/16

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QUAZINONE Chemical Properties,Usage,Production

Description

Ro 13-6438 (70018-51-8) is a selective inhibitor of phosphodiesterase III (PDE III, IC50 = 0.6 μM).

Uses

Cardiotonic.

Uses

Quazinone (Ro 13-6438) is a phosphodiesterase inhibitor and novel cardiotonic agent with vasodilating properties.

References

1) Eigenmann et al. (1984) Cardiovascular profile of Ro 13-6438, a novel positive inotropic agent with vasodilating properties; J. Cardiovasc. Pharmacol., 6 511 2) Holck et al. (1984) Studies on the mechanism of positive inotropic activity of Ro 13-6438, a structurally novel cardiotonic agent with vasodilating properties; J. Cardiovasc. Pharmacol. 6 520

QUAZINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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QUAZINONE Suppliers

China 25 Germany 1 Switzerland 2 United Kingdom 3 United States 9 Global 40

Shanghai EFE Biological Technology Co., Ltd.

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Lanospharma Laboratories Co.,Ltd

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70018-51-8, QUAZINONERelated Search:

ZARDAVERINE RO 20-1724 Vinpocetine ZAPRINAST ROLIPRAM Cilostazol (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE CILOSTAMIDE EHNA HYDROCHLORIDE 2 chlorpyridazine 1,1-diethylguanidine hydrochloride QUAZINONE N'-BENZYLGUANIDINEACETATE 1.1-DIMETHYLGUANIDINE HYDROCHLORIDE CHEMBRDG-BB 4024825 N-(2-CHLORO-BENZYL)-GUANIDINE 1-BENZYLIMIDAZOLIDIN-4-ONE CHEMBRDG-BB 4015994

QUAZINONE

R 13-6438

RO 13-6438

(3R)-6-Chloro-1,5-dihydro-3-methylimidazo[2,1-b]quinazolin-2(3H)-one

Posicor

Imidazo(2,1-B)quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-, (R)-

Quazinona

Quazinona [spanish]

Quazinonum

Quazinonum [latin]

Unii-D1Q7F6C2fp

IMidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-Methyl-, (3R)-

Quazinone (Ro 13-6438)

Ro 13-6438 (Quazinone)

70018-51-8

G Proteins and Cyclic Nucleotides

Cyclic Nucleotide Metabolism

Phosphodiesterase Inhibitors

BioChemical

Cell Biology

Cell Signaling and Neuroscience