ChemicalBook > CAS DataBase List > Cefmenoxime hydrochloride

Cefmenoxime hydrochloride

Product Name
Cefmenoxime hydrochloride
CAS No.
75738-58-8
Chemical Name
Cefmenoxime hydrochloride
Synonyms
Tacef;Cemix;Cefmax;Bestron;Bestcall;Abbott 50192;CEFMENOXIME HCL;CefMenoxiMe SodiuM;SCE-1365(free acid);sce1365hydrochloride
CBNumber
CB7763319
Molecular Formula
C16H18ClN9O5S3
Formula Weight
548.01
MOL File
75738-58-8.mol
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Cefmenoxime hydrochloride Property

Melting point:
>175°C (dec.)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
color 
Off-White to Pale Yellow
InChI
InChI=1/C16H17N9O5S3.ClH/c1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7;/h5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29);1H/b21-8-;/t9-,13-;/s3
InChIKey
HZYJYGJIOCXOTH-AJVJENPNNA-N
SMILES
C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)CSC1=NN=NN1C)(=O)O.Cl |&1:5,7,r|
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Safety

HS Code 
2941906000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26440
Product name
Cefmenoxime (hydrochloride)
Packaging
100mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
26440
Product name
Cefmenoxime (hydrochloride)
Packaging
1g
Price
$601
Updated
2024/03/01
Cayman Chemical
Product number
26440
Product name
Cefmenoxime (hydrochloride)
Packaging
50mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
26440
Product name
Cefmenoxime (hydrochloride)
Packaging
500mg
Price
$335
Updated
2024/03/01
TRC
Product number
C242835
Product name
CefmenoximeHydrochloride
Packaging
500mg
Price
$580
Updated
2021/12/16
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Cefmenoxime hydrochloride Chemical Properties,Usage,Production

Description

Cef menoxime hydrochloride is a third generation cephalosporin antibiotic. Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in the 3-position; like several other compounds containing this structural element (moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella, Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is relatively ineffective against Pseudomonas and Bacteroidea.

Originator

Takeda (Japan)

Uses

A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis.

Uses

antibacterial

Definition

ChEBI: The hemihydrochloride salt of cefmenoxime.

brand name

Cefmax (TAP);TACEF;BESTCALL.

General Description

Cefmenoxime was synthesized by Takeda Pharmaceutical Co. in 1978. It contains aminothiazole and methoxyimino groups in the 7-acyl position and a methyltetrazole group at the 3 position of the cephem nucleus. Cefmenoxime has a wide activity spectrum against gram-positive and gram-negative bacteria, including anaerobes, except Staphylococcus aureus. Cefmenoxime is a member of the so-called third-generation cephalosporins, a recently introduced class of clinically important antibiotics.

Cefmenoxime hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Cefmenoxime hydrochloride Suppliers

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View Lastest Price from Cefmenoxime hydrochloride manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Cefmenoxime hydrochloride 75738-58-8
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
300 MT
Release date
2020-05-23
Career Henan Chemical Co
Product
Cefmenoxime hydrochloride 75738-58-8
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10tons
Release date
2018-12-24

75738-58-8, Cefmenoxime hydrochloride Related Search:

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  • 8-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino-4-[(1-methyltetrazol-5-yl)sulfanylmethyl]-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid hydrochloride (2:1)
  • 7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride
  • 7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride
  • Bestcall
  • Bestron
  • Cemix
  • SCE-1365(free acid)
  • Tacef
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), [6R-[6α,7β(Z)]]-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), (6R,7R)-
  • Abbott 50192
  • Cefmax
  • )(methoxyimino)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-ox
  • ab50912hemihydrochloride
  • cefmenoximehemihydrochloride
  • hydrochloride(2:1),(6r-(6-alpha,7-beta(z)))-o
  • sce1365hydrochloride
  • CEFMENOXIME HCL
  • CEFMENOXIME HYDROCHLORIDE
  • (6R)-7α-[[(2-Amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid·0.5hydrochloride
  • 2Cefmenoxime·Hydrochloride
  • Cefmenoxime Hydrochloride (350 mg)
  • CefMenoxiMe SodiuM
  • (6R,7R)-7-[[(2Z)-(2-AMino-4-thiazolyl)(MethoxyiMino)acetyl]aMino]-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid HeMihydrochloride
  • CefMenoxiMe HCL Sterile (pure)
  • Hydrochloride (syn-isomer)
  • 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
  • CEFMENOXIME HEMIHYDROCHLORIDE;SCE-1365 HEMIHYDROCHLORIDE
  • SCE-1365 hemihydrochloride
  • (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride(2:1)
  • Cefmenoxime hydrochloride USP/EP/BP
  • Cefmenoxime HCl (SCE-1365)
  • Cefmenoxime Hydrochloride (1097771)
  • Cefmenoxime HCL Powder USP Standard
  • Cefmenoxime hydrochloride, 10 mM in DMSO
  • 75738-58-8
  • 75739-58-8
  • 2C16H17N9O5S3HClC32H35ClN18O10S6
  • C16H17N9O5S32HCl
  • C16H17N9O5S312ClH
  • C16H17N9O5S312HCl
  • 2C16H17N9O5S3HCl
  • C32H35ClN18O10S6
  • CEFMAX
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds