ChemicalBook > CAS DataBase List > Thalidomide-O-PEG4-amine
Thalidomide-O-PEG4-amine
- Product Name
- Thalidomide-O-PEG4-amine
- CAS No.
- 2401832-00-4
- Chemical Name
- Thalidomide-O-PEG4-amine
- Synonyms
- Thalidomide-O-PEG4-NH2;Thalidomide-O-PEG4-amine;4-((14-amino-3,6,9,12-tetraoxatetradecyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione, 4-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)oxy]-2-(2,6-dioxo-3-piperidinyl)-;4-[(14-amino-3,6,9,12-tetraoxatetradecan-1-yl)oxy]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione
- CBNumber
- CB78054840
- Molecular Formula
- C23H31N3O9
- Formula Weight
- 493.51
- MOL File
- 2401832-00-4.mol
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Thalidomide-O-PEG4-amine Property
- Boiling point:
- 690.9±55.0 °C(Predicted)
- Density
- 1.321±0.06 g/cm3(Predicted)
- pka
- 10.70±0.40(Predicted)
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Safety
- HS Code
- 2933998090
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-24435
- Product name
- Thalidomide-O-PEG4-Amine
- Purity
- 98%
- Packaging
- 100mg
- Price
- $540
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-24435
- Product name
- Thalidomide-O-PEG4-Amine
- Purity
- 98%
- Packaging
- 250mg
- Price
- $980
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-24435
- Product name
- Thalidomide-O-PEG4-Amine
- Purity
- 98%
- Packaging
- 500mg
- Price
- $1760
- Updated
- 2021/12/16
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Thalidomide-O-PEG4-amine Chemical Properties,Usage,Production
Description
Thalidomide-O-PEG4-Amine is synthesized compound that can react with NHS ester group or carboxylic acid in the presence of EDC or HATU
Uses
Thalidomide-O-PEG4-amine is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
IC 50
Cereblon
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Thalidomide-O-PEG4-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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Thalidomide-O-PEG4-amine Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
2401832-00-4, Thalidomide-O-PEG4-amineRelated Search:
Thalidomide-4-O-C8-NH2
Thalidomide-O-PEG4-Boc
2-(2,6-Dioxo-3-piperidinyl)-4-[2-[2-(2-propyn-1-yloxy)oxy]ethoxy]-1H-isoindole-1,3(2H)dione
Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
Thalidomide-O-PEG4-NHS ester
4-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Thalidomide-O-PEG3-amine HCl
Acetamide, N-[2-[3-[3-(2-aminoethoxy)propoxy]propoxy]ethyl]-2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]-
Thalidomide-O-PEG4-azide