Vesencumab

Product Name: Vesencumab
CAS No.: 1205533-60-3
Chemical Name: Vesencumab
Synonyms: Vesencumab;Vesencumab (anti-NRP1);Research Grade Vesencumab;Research Grade Vesencumab (DHA30101)
CBNumber: CB78080836
Formula Weight: 0
MOL File: Mol file

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Vesencumab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Vesencumab Chemical Properties,Usage,Production

Uses

Vesencumab (MNRP-1685A) is IG1 antibody against neuropilin-1 (NRP-1). Vesencumab binds to NRP-1 and prevents the subsequent coupling of NRP-1 to VEGFR-2. Vesencumab has anti-angiogenic and anti-neoplastic activities. Vesencumab can be used in the research of metastatic solid tumors, including ovarian cancer[1][2].

in vivo

Vesencumab (10 mg/kg, ip, twice a week for 7 weeks) exhibits antitumor effect in mouse SUM159 orthotopic xenograft models^[3].

Animal Model:	Mouse SUM159 orthotopic xenograft models^[3]
Dosage:	10 mg/kg
Administration:	ip, twice a week for 7 weeks
Result:	Inhibited tumor volume and weight.

References

[1] Jonathan Stephens, et al. Rare disease landscape: will the blockbuster model be replaced? Expert Opinion on Orphan Drugs. Volume 2, 2014 - Issue 8.
[2] Zhang J, et al. Diabetic Macular Edema: Current Understanding, Molecular Mechanisms and Therapeutic Implications. Cells. 2022 Oct 25;11(21):3362. DOI:10.3390/cells11213362

Vesencumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Vesencumab Suppliers

China 16 Global 16

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1205533-60-3, VesencumabRelated Search:

clenoliximab Telazorlimab reslizumab Epcoritamab Rinucumab Regavirumab Eblasakimab Timolumab Sotevtamab Olendalizumab

Vesencumab

Research Grade Vesencumab (DHA30101)

Research Grade Vesencumab

Vesencumab (anti-NRP1)

1205533-60-3