Oleclumab

Product Name: Oleclumab
CAS No.: 1803176-05-7
Chemical Name: Oleclumab
Synonyms: Oleclumab;Oleclumab (anti-CD73);Research Grade Oleclumab;Research Grade Oleclumab(DHD46601)
CBNumber: CB78081035
Formula Weight: 0
MOL File: Mol file

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Oleclumab Property

storage temp.: Store at -20°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Oleclumab Chemical Properties,Usage,Production

Uses

The CD73-antagonist antibody oleclumab inhibits cell surface-exposed CD73 and is currently undergoing clinical testing for cancer immunotherapy.

in vivo

Oleclumab (10 mg/kg; ip; every 3 days for 4 doses) increases the proportion of activated CD8⁺ lymphocyte populations in the mouse Balb/c syngeneic CT26 colon cancer tumor model. And Oleclumab significantly inhibits tumor growth^[2].

Animal Model:	Murine, Balb/c, syngeneic CT26 colon carcinoma tumor model^[2]
Dosage:	10 mg/kg
Administration:	ip; 2 time per week, for 2 weeks
Result:	Inhibited tumor growth by 50% or greater from study day 7 to study day 16 when compared with isotype control antibody-treated groups.

Oleclumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Oleclumab Suppliers

China 18 United States 1 Global 19

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1803176-05-7, OleclumabRelated Search:

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Oleclumab

Research Grade Oleclumab(DHD46601)

Oleclumab (anti-CD73)

Research Grade Oleclumab

1803176-05-7