1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE

Product Name: 1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE
CAS No.: 73930-39-9
Chemical Name: 1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE
Synonyms: 1-Phenylcyclopropan-1-amine hydrochloride;TIMTEC-BB SBB008643;1-PhenylcyclopropylaMine HCl;1-PhenylcyclopropanaMine, HCl;1-Phenyl-cyclopropylamine hydroc;1-Phenylcyclopropanamine Hydrochloride;1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE;cyclopropanamine, 1-phenyl-, hydrochloride;1-Phenylcyclopropan-1-aminehydrochloride95%;1-phenyl-cyclopropylamine HCL form, 95%min
CBNumber: CB7836835
Molecular Formula: C9H12ClN
Formula Weight: 169.65128
MOL File: 73930-39-9.mol

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1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE Property

Melting point:: 194.7-194.9 °C
storage temp.: Inert atmosphere,Room Temperature
form: solid
Appearance: White to off-white Solid
InChI: InChI=1S/C9H11N.ClH/c10-9(6-7-9)8-4-2-1-3-5-8;/h1-5H,6-7,10H2;1H
InChIKey: ABUWJOHYZALSMF-UHFFFAOYSA-N
SMILES: C1(N)(C2=CC=CC=C2)CC1.Cl

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Safety

HazardClass: IRRITANT
HS Code: 2921490090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: OTV000611
Product name: 1-Phenylcyclopropanamine hydrochloride
Packaging: 1 g
Price: $179
Updated: 2025/07/31

TCI Chemical

Product number: P3138
Product name: 1-Phenylcyclopropan-1-amine Hydrochloride
Packaging: 200MG
Price: $60
Updated: 2025/07/31

TCI Chemical

Product number: P3138
Product name: 1-Phenylcyclopropan-1-amine Hydrochloride
Packaging: 1G
Price: $150
Updated: 2025/07/31

TRC

Product number: P336613
Product name: 1-PhenylcyclopropanamineHydrochloride
Packaging: 25mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-B0486
Product name: Cyclopropanamine,1-phenyl-,(Hydrochloride)1:1
Purity: 99.77%
Packaging: 1g
Price: $54
Updated: 2021/12/16

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1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE Chemical Properties,Usage,Production

Synthesis

6120-95-2

73930-39-9

The general procedure for the synthesis of 1-phenylcyclopropanamine hydrochloride from 1-phenyl-1-cyclopropanecarboxylic acid is as follows: first, 1-phenylcyclopropanecarboxylic acid (1) was reacted with sodium azide and sulfuric acid in chloroform to produce 1-phenylcyclopropanamine (2). Subsequently, 1-phenylcyclopropanamine was reacted with 2-methanesulfonyl chloride in chloroform under alkaline conditions to prepare to obtain the protected derivative (3), i.e., N-(1-phenylcyclopropyl) homotrimethylbenzenesulfonamide. Next, N-(1-phenylcyclopropyl)homotrimethylbenzenesulfonamide (3) was reacted with N-(4-bromobutyl)phthalimide (4) in DMF in the presence of sodium hydride overnight at room temperature to obtain N-(2- homotrimethylbenzenesulfonyl)-N-(1-phenylcyclopropyl)-4-phthalimidobutylamine (5). Then, phthaloyl was removed by reacting N-(2- homotrimethylbenzenesulfonyl)-N-(1-phenylcyclopropyl)-4-phthalimidobutylamine (5) with aniline hydrochloride and sodium methanol in methanol to produce N-(4-aminobutyl)-N-(1-phenylcyclopropyl)-2- homotrimethylbenzenesulfonamide (6). Next, the free amino group was again protected using 2- homotrimethylbenzenesulfonyl chloride in chloroform with hydrogen chloride to give N-(4-(homotrimethylbenzene-2-sulfonylamino)butyl)-N-(1-phenylcyclopropyl)-2- homotrimethylbenzenesulfonamide (7). Subsequently, a derivative of tetra- homotrimethylbenzene-2-sulfonyl-protected 1,2-bis((N-(1-phenylcyclopropyl)-4-aminobutyl)aminomethyl)cyclopropane (8) was prepared by reacting (7) with 1,2-bis(homotrimethylbenzene-2-sulfonyl- protected 1,2-bis((N-(1-phenylcyclopropyl)-4-amino-butyl)aminomethyl)cyclopropane) in DMF, in the presence of sodium hydride, at room temperature, overnight, to obtain (9). Finally, the homotrimethylbenzene-protecting group was removed using HBr in acetic acid and phenol in dichloromethane to give 1,2-bis((N-(1-phenylcyclopropyl)-4-aminobutyl)aminomethyl)cyclopropane (CGC-11255; SL-11255).

References

[1] Patent: WO2006/86773, 2006, A2. Location in patent: Page/Page column 32-34
[2] Patent: WO2011/119704, 2011, A1. Location in patent: Page/Page column 35-36
[3] Synthetic Communications, 1980, vol. 10, # 2, p. 107 - 110

1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE Suppliers

China 108 India 1 United Kingdom 2 United States 8 Global 119

Accela ChemBio Inc.

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TimTec Corporation

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View Lastest Price from 1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE manufacturers

Career Henan Chemical Co

Product: 1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE 73930-39-9
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 1000KGS
Release date: 2019-12-20

73930-39-9, 1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDERelated Search:

1-PHENYL-CYCLOPROPYLAMINE HYDROCHLORIDE

TIMTEC-BB SBB008643

1-Phenylcyclopropanamine Hydrochloride

Cyclopropanamine, 1-phenyl-, hydrochloride (1:1)

1-Phenylcyclopropan-1-amine hydrochloride

1-Phenyl-cyclopropylamine hydroc

1-PhenylcyclopropylaMine HCl

1-PhenylcyclopropanaMine, HCl

1-Amino-1-phenylcyclopropane hydrochloride, (1-Aminocycloprop-1-yl)benzene hydrochloride

1-Phenylcyclopropan-1-amine hydrochloride 95%

1-Phenylcyclopropan-1-aminehydrochloride95%

cyclopropanamine, 1-phenyl-, hydrochloride

1-phenyl-Cyclopropanamine hydrochloride (1:1)

1-phenyl-cyclopropylamine HCL form, 95%min

73930-39-9

API intermediates

Amines and Anilines