2-OXAZOLECARBONITRILE
- Product Name
- 2-OXAZOLECARBONITRILE
- CAS No.
- 68776-60-3
- Chemical Name
- 2-OXAZOLECARBONITRILE
- Synonyms
- 2-CYANO-OXAZOLE;2-OXAZOLECARBONITRILE;oxazole-2-carbonitrile;1,3-oxazole-2-carbonitrile
- CBNumber
- CB7841994
- Molecular Formula
- C4H2N2O
- Formula Weight
- 94.07
- MOL File
- 68776-60-3.mol
2-OXAZOLECARBONITRILE Property
- Boiling point:
- 165.7±23.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- -3.49±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- C998778
- Product name
- 2-Cyano-oxazole
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FC106345
- Product name
- 2-Cyano-oxazole
- Packaging
- 10mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FC106345
- Product name
- 2-Cyano-oxazole
- Packaging
- 25mg
- Price
- $100
- Updated
- 2021/12/16
- Product number
- FC106345
- Product name
- 2-Cyano-oxazole
- Packaging
- 50mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- FC106345
- Product name
- 2-Cyano-oxazole
- Packaging
- 100mg
- Price
- $258
- Updated
- 2021/12/16
2-OXAZOLECARBONITRILE Chemical Properties,Usage,Production
Synthesis
884539-45-1
68776-60-3
Example 112: Synthesis of 1,3-oxazole-2-carbonitrile; 1,3-oxazole-2-carboxamide (0.98 g, 8.8 mmol, 1.0 eq.) was dissolved in pyridine (17 mL), followed by the addition of phosphorus triclosan (1.2 mL, 12.2 mmol, 1.4 eq.). The reaction mixture was stirred at room temperature for 5 h. The solution was observed to change from a beige slurry to a brown color. After completion of the reaction, the mixture was diluted with ice water and extracted with ether. The aqueous layer was adjusted to pH 3 with 6 M hydrochloric acid and extracted again with ether. The combined ether extracts were washed sequentially with water and saturated brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 1,3-oxazole-2-carbonitrile as an amber colored oil (0.61 g, 74% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ 8.608 (s, 1H), 7.67 (s, 1H).
References
[1] Patent: WO2006/43145, 2006, A1. Location in patent: Page/Page column 131
[2] Patent: WO2010/45009, 2010, A1. Location in patent: Page/Page column 40-41
[3] Patent: WO2010/45015, 2010, A1. Location in patent: Page/Page column 27
[4] Patent: WO2010/45016, 2010, A1. Location in patent: Page/Page column 20
2-OXAZOLECARBONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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