OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE

Product Name: OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE
CAS No.: 53052-06-5
Chemical Name: OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE
Synonyms: BUTTPARK 19\09-84;OXAZOLO[4,5-B]PYRIDINE-2-THIOL;2-oxazolo[4,5-b]pyridinethiolate;OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE;[1,3]Oxazolo[4,5-b]pyridin-2-thiol;3H-OXAZOLO[4,5-B]PYRIDINE-2-THIONE;[1,3]OXAZOLO[4,5-B]PYRIDINE-2-THIOL;Oxazolo[4,5-b]pyridine-2(3H)-thione;1,3-Oxazolo[4,5-b]pyridin-2(3H)thione;Oxazolo[4,5-b]pyridin-2(3H)thione,99%
CBNumber: CB1687125
Molecular Formula: C6H4N2OS
Formula Weight: 152.17
MOL File: 53052-06-5.mol

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OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE Property

Melting point:: 243-246 °C
Density: 1.402 (estimate)
refractive index: 1.6430 (estimate)
storage temp.: 2-8°C
form: solid
Appearance: White to off-white Solid
CAS DataBase Reference: 53052-06-5

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Safety

Hazard Codes: Xi
Safety Statements: 24/25
HazardClass: IRRITANT
HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H320Causes eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: O846558
Product name: Oxazolo[4,5-b]pyridine-2(3H)-thione
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 044922
Product name: [1,3]Oxazolo[4,5-b]pyridine-2-thiol
Purity: >95%
Packaging: 1g
Price: $44
Updated: 2021/12/16

Matrix Scientific

Product number: 044922
Product name: [1,3]Oxazolo[4,5-b]pyridine-2-thiol
Purity: >95%
Packaging: 500mg
Price: $62
Updated: 2021/12/16

AK Scientific

Product number: Z4832
Product name: Oxazolo[4,5-b]pyridine-2-thiol
Packaging: 1g
Price: $111
Updated: 2021/12/16

Matrix Scientific

Product number: 044922
Product name: [1,3]Oxazolo[4,5-b]pyridine-2-thiol
Purity: >95%
Packaging: 5g
Price: $209
Updated: 2021/12/16

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OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE Chemical Properties,Usage,Production

Chemical Properties

Beige crystalline powder

Synthesis

16867-03-1

140-89-6

53052-06-5

Step 1: Synthesis of oxazolo[4,5-b]pyridine-2(3H)thione 2-Amino-3-hydroxypyridine (5.0 g, 45.45 mmol) and potassium ethylxanthate (8.0 g, 49.99 mmol) were dissolved in pyridine (50 mL), and the reaction was stirred at 110 °C overnight. Upon completion of the reaction, the mixture was cooled to 0 °C, ice water was added and acidified with concentrated hydrochloric acid. The precipitated solid was collected by filtration and dried under vacuum to afford the target product oxazolo[4,5-b]pyridine-2(3H)thione (6.0 g, 86.95% yield). Product characterization data: 1H NMR (DMSO-d6, 300 MHz): δ 8.24-8.22 (d, 1H), 7.90-7.87 (d, 1H), 7.30-7.26 (m, 1H). LCMS: m/z 153.0 [M + H]+.

References

[1] Patent: WO2015/104688, 2015, A1. Location in patent: Page/Page column 36
[2] Patent: US2016/340366, 2016, A1. Location in patent: Paragraph 0205; 0206
[3] Monatshefte fur Chemie, 2011, vol. 142, # 9, p. 895 - 899
[4] Journal of Organic Chemistry, 1995, vol. 60, # 17, p. 5721 - 5725
[5] European Journal of Medicinal Chemistry, 2005, vol. 40, # 1, p. 15 - 23

OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE Suppliers

Belgium 1 China 64 Czech Republic 1 Germany 2 India 1 Japan 1 United Kingdom 3 United States 14 Global 87

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View Lastest Price from OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE manufacturers

Career Henan Chemical Co

Product: OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE 53052-06-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-26

53052-06-5, OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONERelated Search:

ETHYL 2-OXAZOLECARBOXYLATE Oxazolo[4,5-c]pyridine-2(3H)-thione Oxazolo[5,4-b]pyridine 5-OXAZOLECARBOXALDEHYDE Oxazolo[4,5-b]pyridine Oxazolo[5,4-b]pyridin-2(1H)-one (6CI,9CI) Oxazolo[4,5-c]pyridin-2(3H)-one 2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one Oxazole-2-carbaldehyde 5-ISOXAZOLEMETHANOL 2-OXAZOLEMETHANOL Oxazolo[4,5-c]pyridin-2-amine (9CI) 2-OXAZOLECARBONITRILE Oxazolo[5,4-b]pyridine-2(1H)-thione OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE 2-(METHYLTHIO)OXAZOLO[4,5-B]PYRIDINE BUTTPARK 18\09-08 BUTTPARK 18\09-10

[1,3]Oxazolo[4,5-b]pyridin-2-thiol

Oxazolo[4,5-b]pyridine-2(3H)-thione

1,3-Oxazolo[4,5-b]pyridin-2(3H)thione

2,3-Dihydro-2-thioxo-1,3-oxazolo[4,5-b]pyridine

Oxazolo[4,5-b]pyridin-2(3H)thione,99%

3H-[1,3]oxazolo[4,5-b]pyridine-2-thione

OXAZOLO[4,5-B]PYRIDIN-2(3H)THIONE

OXAZOLO[4,5-B]PYRIDINE-2-THIOL

[1,3]OXAZOLO[4,5-B]PYRIDINE-2-THIOL

3H-OXAZOLO[4,5-B]PYRIDINE-2-THIONE

BUTTPARK 19\09-84

1,3-Oxazolo[4,5-b]pyridin-2(3H)thione 98%

2-oxazolo[4,5-b]pyridinethiolate

Oxazolo[4,5-b]pyridine-2(3H)-thione (9CI, ACI)

53052-06-5

C6H4N2OS