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DEVAZEPIDE

Product Name
DEVAZEPIDE
CAS No.
103420-77-5
Chemical Name
DEVAZEPIDE
Synonyms
718;MK-329;L-364718;evazepide;DEVAZEPIDE;EVAZEPIDE, PANOS;Betaxolol Impurity 12;(3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one;(S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide;N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE
CBNumber
CB7849798
Molecular Formula
C25H20N4O2
Formula Weight
408.45
MOL File
103420-77-5.mol
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DEVAZEPIDE Property

Boiling point:
758.6±60.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >5mg/mL
pka
13.25±0.40(Predicted)
form 
powder
color 
white to off-white
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Safety

Hazard Codes 
T+
Risk Statements 
28
Safety Statements 
28-36/37-45
RIDADR 
UN 2811 6.1 / PGI
WGK Germany 
3
RTECS 
NL5994460
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D3821
Product name
Devazepide
Purity
≥98% (HPLC), powder
Packaging
5mg
Price
$123.6
Updated
2024/03/01
Sigma-Aldrich
Product number
D3821
Product name
Devazepide
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$825
Updated
2024/03/01
Tocris
Product number
2304
Product name
Devazepide
Purity
≥99%(HPLC)
Packaging
50
Price
$1135
Updated
2021/12/16
Tocris
Product number
2304
Product name
Devazepide
Purity
≥99%(HPLC)
Packaging
10
Price
$270
Updated
2021/12/16
Usbiological
Product number
255128
Product name
Devazepide
Packaging
10mg
Price
$531
Updated
2021/12/16
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DEVAZEPIDE Chemical Properties,Usage,Production

Uses

Antagonist (cholecystokinin).

Uses

Devazepide has been used as a cholecystokinin receptor 1 (CCK1R) antagonist in human embryonic kidney 293T cells and in human pancreatic slices.

Definition

ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f r treatment of gastrointestinal disorders.

General Description

Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone.

Biochem/physiol Actions

Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist.

storage

Store at +4°C

DEVAZEPIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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DEVAZEPIDE Suppliers

China 14 Germany 1 United Kingdom 4 United States 10 Global 29
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8449
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65

103420-77-5, DEVAZEPIDERelated Search:

Pranazepide N-(2-OXO-5-PHENYL-2,3-DIHYDRO-1H-BENZO[E][1,4]DIAZEPIN-3-YL)-ACETAMIDE 3-AMINO-5-PHENYL-1,3-DIHYDRO-2H-1,4-BENZODIAZEPIN-2-ONE DEVAZEPIDE tarazepide 3-AMINO-5-METHYL-1,3-DIHYDRO-BENZO[E][1,4]DIAZEPIN-2-ONE

  • N-[(3S)-2,3-DIHYDRO-1-METHYL-2-OXO-5-PHENYL-1H-1,4-BENZODIAZEPIN-3-YL]-1H-INDOLE-2-CARBOXAMIDE
  • DEVAZEPIDE
  • EVAZEPIDE, PANOS
  • (3S)-1-Methyl-3-[(1H-indol-2-yl)carbonylamino]-5-phenyl-1H-1,4-benzodiazepin-2(3H)-one
  • L-364718
  • MK-329
  • (S)-N-(2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)indole-2-carboxamide
  • 1H-Indole-2-carboxamide, N-[(3S)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]-
  • 718
  • evazepide
  • Betaxolol Impurity 12
  • 103420-77-5
  • C25H20N4O2