ChemicalBook > CAS DataBase List > 2-Cyanoacetamide

2-Cyanoacetamide

Product Name
2-Cyanoacetamide
CAS No.
107-91-5
Chemical Name
2-Cyanoacetamide
Synonyms
CYANOACETAMIDE;ACETAMIDE, 2-CYANO-;Cyanacetamide;Kyanacetamid;CYANOACETIC AMIDE;CYAC;2-CAA;usafkf-14;USAF kf-14;Cyanacetamid
CBNumber
CB7852727
Molecular Formula
C3H4N2O
Formula Weight
84.08
MOL File
107-91-5.mol
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2-Cyanoacetamide Property

Melting point:
119-121 °C(lit.)
Boiling point:
154.34°C (rough estimate)
Density 
1,4 g/cm3
refractive index 
1.5110 (estimate)
Flash point:
419 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
cold water: soluble1gm in 6.5ml
pka
-1.27±0.10(Predicted)
form 
Crystalline Powder
color 
White to light cream
Odor
Odorless
Water Solubility 
soluble
Merck 
14,2688
BRN 
878221
CAS DataBase Reference
107-91-5(CAS DataBase Reference)
NIST Chemistry Reference
Acetamide, 2-cyano-(107-91-5)
EPA Substance Registry System
2-Cyanoacetamide (107-91-5)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
22-26-28A
RIDADR 
UN 3439 6.1/PG 3
WGK Germany 
2
RTECS 
AB5950000
TSCA 
Yes
PackingGroup 
III
HS Code 
29159080
HS Code 
29269095
Hazardous Substances Data
107-91-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
108448
Product name
Cyanoacetamide
Purity
99%
Packaging
100g
Price
$62.7
Updated
2024/03/01
Sigma-Aldrich
Product number
108448
Product name
Cyanoacetamide
Purity
99%
Packaging
500g
Price
$201
Updated
2024/03/01
TCI Chemical
Product number
C0437
Product name
2-Cyanoacetamide
Purity
>98.0%(GC)
Packaging
25g
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
C0437
Product name
2-Cyanoacetamide
Purity
>98.0%(GC)
Packaging
500g
Price
$90
Updated
2024/03/01
Alfa Aesar
Product number
A12482
Product name
Cyanoacetamide, 99%
Packaging
100g
Price
$32.1
Updated
2024/03/01
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2-Cyanoacetamide Chemical Properties,Usage,Production

Chemical Properties

White or light yellow needle crystal or powder. Slightly soluble in water, easily soluble in ethanol.

Uses

2-Cyanoacetamide was used in spectrofluorimetric method for the determination of some antihistaminic H1 receptor antagonist drugs such as ebastine, cetirizine dihydrochloride and fexofenadine hydrochloride. It may be used in fluorometric determination of 3,4-dihydroxyphenylalanine. It was used as post column fluorigenic derivatizing agent for the bio-analysis and pharmacokinetics of chitosan ester in rabbit serum. Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence and is useful for the automated analysis of carbohydrates as borate complexes. It can also be used in the synthesis of heterocyclic compounds such as pyrazole, pyridine and pyrimidine derivatives. Moreover, it can also be applied for the spectrophotometric assay of the enzyme activity of cellulose in related host cells.

Preparation

Cyanoacetamide can be prepared from ethyl cyanoacetate and ammonia. Cool the ethyl cyanoacetate to below 200°C, add concentrated ammonia water to react, and the mixture turns from turbid to clear. After cooling in cold water for 20 minutes, a precipitate is precipitated. After filtration and drying, the crude product is obtained, and then the crude product of cyanoacetamide is added. In the boiling ethanol, after dissolving it, add a small amount of activated carbon for decolorization and purification, filter, cool the filtrate to separate out the precipitate, and dry it at 80-100 ℃ to obtain the fine cyanoacetamide.

Definition

2-Cyanoacetamide is an acetic amide with a nitrile functional group. It is a codon of glutamine that directs the placement of glutamine into a polypeptide.

General Description

Cyanoacetamide is the starting reagent for vitamin B6 synthesis. It reacts with reducing carbohydrates in borate buffer to give intense fluorescence andis useful for the automated analysis of carbohydrates as borate complexes.

Purification Methods

Crystallise the amide from MeOH/dioxane (6:4), then water and dry it over P2O5 under vacuum. [Beilstein 2 IV 1891.]

2-Cyanoacetamide Preparation Products And Raw materials

Raw materials

Ethyl acetate Methyl cyanoacetate Ethyl cyanoacetate

Preparation Products

Disperse Yellow H-4GL Allopurinol METHYL 3-AMINO-6-METHYLTHIOPHENO[2,3-B]PYRIDINE-2-CARBOXYLATE Buspirone 2-HYDROXY-6-(TRIFLUOROMETHYL)NICOTINIC ACID 2-Chloro-6-methyl-3-pyridinecarbonitrile 2-Chloro-6-methylpyridine-4-carboxylic acid 3-AMINO-6-METHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE 6-Methyl-1H-pyrazolo[3,4-b]pyridin-3-amine Malononitrile 5-BROMO-2-CHLORO-4,6-DIMETHYLNICOTINONITRILE Olprinone 1,4,6-Trimethyl-1H-pyrazolo[3,4-b]pyridin-3-ylamine ,97% 2,4-DICYANO-3-METHYLGLUTARAMIDE 2-CHLORO-6-METHYLPYRIDINE-4-CARBONYL CHLORIDE ETHYL 2-CHLORO-3-CYANO-6-METHYLISONICOTINATE 2-AMINO-5-PHENYL-3-THIOPHENECARBOXAMIDE 2,4,6-Triaminopyrimidine 2-AMINO-6-METHYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-3-CARBOXAMIDE 2,6-DICHLORO-3-HYDROXYPYRIDINE-4-CARBOXYLIC ACID 3-Cyano-4,6-dimethyl-2-hydroxypyridine Entacapone 3-aminopropanamide 4,7-DIHYDRO-4-OXO-3H-PYRROLO[2,3-D][1,2,3]TRIAZINE-5-CARBOXAMIDE 2,2-Dibromo-2-cyanoacetamide 3-Cyano-6-methyl-2(1H)-pyridinone 2-Chloro-3-cyano-4,6-dimethylpyridine 2-Methylisonicotinic acid 5-BROMO-4,6-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE Milrinone 4-AMINOPYRIMIDINE-5-CARBOXAMIDE 4,6-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE 2-cyano-2-[2,3-dihydro-3-(tetrahydro-2,4,6-trioxo-5(2H)-pyrimidinylidene)-1H-isoindol-1-ylidene]-N-methylacetamide
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2-Cyanoacetamide Suppliers

Americas 1 Australia 1 Belgium 3 Canada 3 China 485 Europe 5 France 2 Germany 10 India 72 Italy 1 Japan 8 Slovakia 1 South Korea 2 Switzerland 4 The Netherlands 2 Ukraine 1 United Kingdom 9 United States 45 Global 655
Ark Pharm, Inc.
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View Lastest Price from 2-Cyanoacetamide manufacturers

Taicang Puyuan Pharmaceutical Co., Ltd.
Product
2-Cyanoacetamide 107-91-5
Price
US $0.00/kg
Min. Order
1kg
Purity
≥99%
Supply Ability
500 tons
Release date
2025-01-02
Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Cyanoacetamide 107-91-5
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-20
HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
2-Cyanoacetamide 107-91-5
Price
US $999.00-666.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-08-14

107-91-5, 2-CyanoacetamideRelated Search:

N,N-Dimethylacetamide Acetaminophen Acetamide Thioacetamide Cyanoacetohydrazide 4'-CHLOROACETANILIDE DIACETAMIDE 2-Phenylacetamide Chloroacetamide 2-Iodoacetamide N-Methyl-N-(methylcarbamoyl)cyanoacetamide,N-Methyl-N-(methylcarbamoyl)cyanoacetamide 2,4-DICYANO-3-METHYLGLUTARAMIDE 1-CYANOACETYLPIPERIDINE N-CYANOACETYLMORPHOLINE N-CYANOACETYLPYRROLIDINE Cyanoacetylurea N-CYANOACETYLURETHANE 2-Cyano-N,N-diethylacetamide

  • amidkyselinykyanoctove
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  • CyanoacetaMide, 95+%
  • Cyanide acetaMide
  • Milrinone Impurity T
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  • 2-cyanoethanamide
  • LABOTEST-BB LT01406239
  • MALONAMIDONITRILE
  • CYANOACETAMIDE
  • CYANOACETIC AMIDE
  • CYAC
  • Cyanacetamid
  • 3-Nitrilo-propionamide
  • Amid kyseliny kyanoctove
  • 2-CAA
  • 2-CYANOACETAMIDE
  • 2-Cyanacetamid
  • 2-Cyanoacetamide &gt
  • 2-Cyanoacetamide ISO 9001：2015 REACH
  • Test Sample Is Free----2-Cyanoacetamide (CAA) CAS 107-91-5
  • Cyanoacetamide 98% For Synthesis
  • 107-91-5
  • NCCH2CONH2
  • Carbonyl Compounds
  • Building Blocks
  • Amides
  • Organic Building Blocks
  • used as medicine, dye and plating solution intermediates
  • fine chemicals
  • amine series
  • Agrochemicals
  • Carbonyl Compounds
  • Fluorescence