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Aclatonium napadisilate

Product Name
Aclatonium napadisilate
CAS No.
55077-30-0
Chemical Name
Aclatonium napadisilate
Synonyms
TM 723;Abovis;Aclatonium;aclatonium napadisilate;aclatonium napadisylate;(2-Acetoxypropionyl)choline;Napadisilic acid aclatonium;Aclatonium napadisilate USP/EP/BP;2-(2-acetyloxy-1-oxopropoxy)ethyl-trimethylammonium;2-[2-(Acetyloxy)-1-oxopropyloxy]-N,N,N-trimethylethanaminium
CBNumber
CB7855263
Molecular Formula
C30H44N2O14S2
Formula Weight
720.80536
MOL File
55077-30-0.mol
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Aclatonium napadisilate Property

Melting point:
189-191°
solubility 
DMSO (Slightly), Water (Slightly)
form 
Solid
color 
Crystals
Stability:
Hygroscopic
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Safety

Toxicity
LD50 in mice: 15 g/kg orally, 826 mg/kg s.c. (Miura); in dogs: >10 g/kg orally (Takai)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0079045
Product name
2-(2-ACETYLOXYPROPANOYLOXY)ETHYL-(2-(2-(2-ACETYLOXYPROPANOYLOXY)ETHYL-DIMETHYL-AMMONIO)ETHYL)-DIMETHYL-AZANIUM NAPHTHALENE-1,5-DISULFONATE
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0079045
Product name
2-(2-ACETYLOXYPROPANOYLOXY)ETHYL-(2-(2-(2-ACETYLOXYPROPANOYLOXY)ETHYL-DIMETHYL-AMMONIO)ETHYL)-DIMETHYL-AZANIUM NAPHTHALENE-1,5-DISULFONATE
Purity
95.00%
Packaging
10G
Price
$1334.03
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
18446
Product name
AclatoniumNapadisilate
Packaging
25mg
Price
$1500
Updated
2021/12/16
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Aclatonium napadisilate Chemical Properties,Usage,Production

Originator

Abovis ,Toyama ,Japan ,1981

Uses

Aclatonium Napadisilate is a useful bioactive therapeutic agent for autoimmune diseases. A cholinergic agonist.

Manufacturing Process

5.2 g of bis(choline)-naphthalene-1,5-disulfonate was suspended in 30 ml of acetonitrile, and 10 g of lactic acid anhydride diacetate was added thereto. This mixture was refluxed for 3 hours. The resulting reaction mixture was allowed to stand at room temperature while cooling to precipitate the desired product crystals, which were collected by filtration. 5.5 g (76% yield) of the desired product having a melting point of 189°C to 191°C were obtained.

Therapeutic Function

Cholinergic

Safety Profile

Poison by intravenous route.Moderately toxic by subcutaneous route. An experimentalteratogen. Other experimental reproductive effects. Whenheated to decomposition it emits toxic fumes of NOx andSOx. A cholinergic agent.

Aclatonium napadisilate Preparation Products And Raw materials

Raw materials

Choline hydroxide Isopropyl acetate

Preparation Products

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Aclatonium napadisilate Suppliers

China 28 Germany 1 India 1 United States 2 Global 32
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71

55077-30-0, Aclatonium napadisilateRelated Search:

Ammonium sulfamate Ethyl 2,4-dioxovalerate Cisatracurium besylate ISOXADIFEN-ETHYL Naphthalene-2-sulfonic acid Ethyl acrylate Sodium triacetoxyborohydride SILICON TETRAACETATE Ethylparaben acetic acid, triethoxy-, ethyl ester Diacerein Ethyl propiolate Ethyl acetate Ethyl cyanoacetate Ethanol Trimethylamine Acetoxyacetic acid Trinexapac-ethyl

  • 2-(2-acetyloxypropanoyloxy)ethyl-[2-[2-(2-acetyloxypropanoyloxy)ethyl-dimethyl-ammonio]ethyl]-dimethyl-azanium naphthalene-1,5-disulfonate
  • aclatonium napadisilate
  • Aclatonium
  • 1,5-Naphthalenedisulfonic acid, ion(2-), bis[2-[2-(acetyloxy)-1-oxopropoxy]-N,N,N-trimethylethanaminium] (9CI)
  • Abovis
  • aclatonium napadisylate
  • 2-(2-acetyloxy-1-oxopropoxy)ethyl-trimethylammonium
  • Ethanaminium, 2-[2-(acetyloxy)-1-oxopropoxy]-N,N,N-trimethyl-, 1,5-naphthalenedisulfonate (2:1)
  • TM 723
  • (2-acetyllactoyloxyethyl)trimethylammonium 1,5-naphthalenedisulfonate
  • (2-acetyllactoyloxyethyl)trimethylammonium hemi-1,5-naphthalenedisulfonate
  • (2-Acetoxypropionyl)choline
  • 2-[2-(Acetyloxy)-1-oxopropyloxy]-N,N,N-trimethylethanaminium
  • Napadisilic acid aclatonium
  • 2-(2-acetyloxypropanoyloxy)ethyl-trimethylazanium,naphthalene-1,5-disulfonate
  • Aclatonium napadisilate USP/EP/BP
  • 2-[2-(Acetyloxy)-1-oxopropoxy]-N,N,N-trimethylethanaminium-1,5-naphthalenedisulfonate
  • 55077-30-0
  • C30H46N2O14S2
  • C30H44N2O14S2