ChemicalBook > CAS DataBase List > Octenidine dihydrochloride
Octenidine dihydrochloride
- Product Name
- Octenidine dihydrochloride
- CAS No.
- 70775-75-6
- Chemical Name
- Octenidine dihydrochloride
- Synonyms
- Octenidine hydrochloride;SOT360;Octenidine DiHCl;Otinidine hydrochloride;ocenidine dihydrochloride;OCTENIDINE DIHYDROCHLORIDE;Ortinidine dihydrochloride;TRANS-2-NONENAL 18829-56-6;OctenidineDihydrochloride>Octenidine dihydrochloride 97%
- CBNumber
- CB7879838
- Molecular Formula
- C36H64Cl2N4
- Formula Weight
- 623.82616
- MOL File
- 70775-75-6.mol
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Octenidine dihydrochloride Property
- Melting point:
- 215-217℃
- Density
- 1.046[at 20℃]
- vapor pressure
- 0Pa at 25℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Soluble in dimethyl sulfoxide and methanol.
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 14.2g/L at 20℃
- Merck
- 14,6754
- Stability:
- Hygroscopic
- InChI
- InChI=1S/C36H62N4.2ClH/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2;;/h23-26,31-34H,3-22,27-30H2,1-2H3;2*1H
- InChIKey
- SMGTYJPMKXNQFY-UHFFFAOYSA-N
- SMILES
- [N+]1(CCCCCCCCCC[N+]2C=CC(NCCCCCCCC)=CC=2)=CC=C(NCCCCCCCC)C=C1.[Cl-].[Cl-]
- LogP
- 1.5 at 23℃
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Safety
- HS Code
- 2933399990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
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N-Bromosuccinimide Price
TCI Chemical
- Product number
- O0388
- Product name
- Octenidine Dihydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 1g
- Price
- $29
- Updated
- 2024/03/01
TCI Chemical
- Product number
- O0388
- Product name
- Octenidine Dihydrochloride
- Purity
- >98.0%(HPLC)(N)
- Packaging
- 5g
- Price
- $114
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- H62257
- Product name
- Octenidine dihydrochloride, 98%
- Packaging
- 1g
- Price
- $34.9
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- H62257
- Product name
- Octenidine dihydrochloride, 98%
- Packaging
- 5g
- Price
- $137
- Updated
- 2024/03/01
TRC
- Product number
- O239150
- Product name
- Octenidine Dihydrochloride
- Packaging
- 5g
- Price
- $120
- Updated
- 2021/12/16
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Octenidine dihydrochloride Chemical Properties,Usage,Production
Description
The antiseptic agent octenidine dihydrochloride (OCT) was developed by Sterling Winthrop (WIN41464-2) in the 1980s as an alternative to the anti-plaque agent CHX and successfully tested in vitro and in vivo. OCT has a broad spectrum of activity with similar effectiveness against Gram-negative and Gram-positive bacteria, fungi, and yeasts. Moreover, it has been shown that it may effectively interfere with the co-aggregation of dental plaque microbial colonizers without disturbing the normal, healthy oral flora. In a standardized comparison of antimicrobial activity ofthe antiseptic agents triclosan, polyvinylpyrrolidone-iodine, OCT, polyhexamethylene biguanide, and Chlorhexidine digluconat (CHX) using the min-imal effective concentration and minimum bactericidal con-centration, OCT was the most effective active agent of alltested antimicrobial substances. In other studies, the antibacterial and antiplaque efficacy of OCT was equal to or even greater than that of CHX[1].
Uses
Octenidine is an antiseptic (topical). Octenidine is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative.
Uses
Octenidine dihydrochloride is used as a antiseptic for skin, mucous Membranes and wounds.
Application
Octenidine dihydrochloride is a cationic antiseptic that belongs to the bispyridine class of chemicals. Its action is binding to anionic structures of the cell membrane, further bursting the membrane. It has activity against Gram-positive and Gram-negative bacteria. It was effective in oral hygiene, preventing plaque and gingivitis, as a whole body wash for methicillin-resistant S. aureus decolonization and skin disinfection of premature newborn infants. Octenidine concentrations of less than 1.5 μM (0.94 μg/mL) reduced each microbial population by more than 99% within 15 minutes. Staphylococcus epidermidis was the most susceptible of the test organisms, and E. coli and Candida albicans were the least susceptible. Octenidine was more active than chlorhexidine against each test strain. This antiseptic has not been established in veterinary medicine for skin preparation but is used for wound cleansing.
Flammability and Explosibility
Not classified
References
[1] A. Welk. “Antibacterial and antiplaque efficacy of a commercially available octenidine-containing mouthrinse.” Clinical Oral Investigations 20 1 (2015): 1469–1476.
Octenidine dihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Octenidine dihydrochloride manufacturers
Jinan Million Pharmaceutical Co., Ltd
- Product
- Octenidine dihydrochloride 70775-75-6
- Price
- US $1.00/kg
- Min. Order
- 0.10000000kg
- Purity
- 99%
- Supply Ability
- 200KG
- Release date
- 2024-10-12
Hebei Zhuanglai Chemical Trading Co Ltd
- Product
- Octenidine Dihydrochloride 70775-75-6
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2024-11-19
Hebei Zhuanglai Chemical Trading Co Ltd
- Product
- Octenidine HCl 70775-75-6
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2024-11-26
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