Octenidine dihydrochloride

Product Name: Octenidine dihydrochloride
CAS No.: 70775-75-6
Chemical Name: Octenidine dihydrochloride
Synonyms: Octenidine hydrochloride;SOT360;Octenidine DiHCl;Otinidine hydrochloride;ocenidine dihydrochloride;OCTENIDINE DIHYDROCHLORIDE;Ortinidine dihydrochloride;TRANS-2-NONENAL 18829-56-6;OctenidineDihydrochloride>Octenidine dihydrochloride 97%
CBNumber: CB7879838
Molecular Formula: C36H64Cl2N4
Formula Weight: 623.82616
MOL File: 70775-75-6.mol

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Octenidine dihydrochloride Property

Melting point:: 215-217℃
Density: 1.046[at 20℃]
vapor pressure: 0Pa at 25℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: Soluble in dimethyl sulfoxide and methanol.
form: Solid
color: White to Off-White
Water Solubility: 14.2g/L at 20℃
Merck: 14,6754
Stability:: Hygroscopic
InChI: InChI=1S/C36H62N4.2ClH/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2;;/h23-26,31-34H,3-22,27-30H2,1-2H3;2*1H
InChIKey: SMGTYJPMKXNQFY-UHFFFAOYSA-N
SMILES: [N+]1(CCCCCCCCCC[N+]2C=CC(NCCCCCCCC)=CC=2)=CC=C(NCCCCCCCC)C=C1.[Cl-].[Cl-]
LogP: 1.5 at 23℃

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Safety

HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TCI Chemical

Product number: O0388
Product name: Octenidine Dihydrochloride
Purity: >98.0%(HPLC)(N)
Packaging: 1g
Price: $29
Updated: 2024/03/01

TCI Chemical

Product number: O0388
Product name: Octenidine Dihydrochloride
Purity: >98.0%(HPLC)(N)
Packaging: 5g
Price: $114
Updated: 2024/03/01

Alfa Aesar

Product number: H62257
Product name: Octenidine dihydrochloride, 98%
Packaging: 1g
Price: $34.9
Updated: 2024/03/01

Alfa Aesar

Product number: H62257
Product name: Octenidine dihydrochloride, 98%
Packaging: 5g
Price: $137
Updated: 2024/03/01

TRC

Product number: O239150
Product name: Octenidine Dihydrochloride
Packaging: 5g
Price: $120
Updated: 2021/12/16

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Octenidine dihydrochloride Chemical Properties,Usage,Production

Description

The antiseptic agent octenidine dihydrochloride (OCT) was developed by Sterling Winthrop (WIN41464-2) in the 1980s as an alternative to the anti-plaque agent CHX and successfully tested in vitro and in vivo. OCT has a broad spectrum of activity with similar effectiveness against Gram-negative and Gram-positive bacteria, fungi, and yeasts. Moreover, it has been shown that it may effectively interfere with the co-aggregation of dental plaque microbial colonizers without disturbing the normal, healthy oral flora. In a standardized comparison of antimicrobial activity ofthe antiseptic agents triclosan, polyvinylpyrrolidone-iodine, OCT, polyhexamethylene biguanide, and Chlorhexidine digluconat (CHX) using the min-imal effective concentration and minimum bactericidal con-centration, OCT was the most effective active agent of alltested antimicrobial substances. In other studies, the antibacterial and antiplaque efficacy of OCT was equal to or even greater than that of CHX[1].

Uses

Octenidine is an antiseptic (topical). Octenidine is a cationic surfactant and bis-(dihydropyridinyl)-decane derivative.

Uses

Octenidine dihydrochloride is used as a antiseptic for skin, mucous Membranes and wounds.

Application

Octenidine dihydrochloride is a cationic antiseptic that belongs to the bispyridine class of chemicals. Its action is binding to anionic structures of the cell membrane, further bursting the membrane. It has activity against Gram-positive and Gram-negative bacteria. It was effective in oral hygiene, preventing plaque and gingivitis, as a whole body wash for methicillin-resistant S. aureus decolonization and skin disinfection of premature newborn infants. Octenidine concentrations of less than 1.5 μM (0.94 μg/mL) reduced each microbial population by more than 99% within 15 minutes. Staphylococcus epidermidis was the most susceptible of the test organisms, and E. coli and Candida albicans were the least susceptible. Octenidine was more active than chlorhexidine against each test strain. This antiseptic has not been established in veterinary medicine for skin preparation but is used for wound cleansing.

Flammability and Explosibility

Not classified

References

[1] A. Welk. “Antibacterial and antiplaque efficacy of a commercially available octenidine-containing mouthrinse.” Clinical Oral Investigations 20 1 (2015): 1469–1476.

Octenidine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Octenidine dihydrochloride Suppliers

Americas 1 Belgium 1 Canada 3 China 201 China Hong Kong 1 Europe 1 France 3 Germany 4 India 20 Japan 1 Poland 2 Spain 1 Switzerland 2 The Netherlands 1 United Kingdom 5 United States 30 Global 277

TCI Chemicals (India) Pvt. Ltd.

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Triveni chemicals

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Belchem Industries (India) Private Limited

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SynZeal Research Pvt Ltd

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CRD Industries

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Clearsynth Labs

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SR Chemexon Pharmachem

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Pharmaffiliates Analytics and Synthetics P. Ltd

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A.J Chemicals

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View Lastest Price from Octenidine dihydrochloride manufacturers

Jinan Million Pharmaceutical Co., Ltd

Product: Octenidine dihydrochloride 70775-75-6
Price: US $1.00/kg
Min. Order: 0.10000000kg
Purity: 99%
Supply Ability: 200KG
Release date: 2024-10-12

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Octenidine Dihydrochloride 70775-75-6
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-19

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Octenidine HCl 70775-75-6
Price: US $150.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 500kg
Release date: 2024-11-26

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