ChemicalBook > CAS DataBase List > INDEX NAME NOT YET ASSIGNED
INDEX NAME NOT YET ASSIGNED
- Product Name
- INDEX NAME NOT YET ASSIGNED
- CAS No.
- 2512228-06-5
- Chemical Name
- INDEX NAME NOT YET ASSIGNED
- Synonyms
- Propargyl-PEG1-C2-CONHS ester;2,5-Dioxopyrrolidin-1-yl 3-(2-(prop-2-yn-1-yloxy)ethoxy)propanoate
- CBNumber
- CB79012511
- Molecular Formula
- C12H15NO6
- Formula Weight
- 269.25
- MOL File
- 2512228-06-5.mol
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INDEX NAME NOT YET ASSIGNED Property
- Boiling point:
- 389.8±50.0 °C(Predicted)
- Density
- 1.28±0.1 g/cm3(Predicted)
- form
- Solid
- color
- White to off-white
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INDEX NAME NOT YET ASSIGNED Chemical Properties,Usage,Production
Biological Activity
Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.
INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials
Raw materials
Preparation Products
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INDEX NAME NOT YET ASSIGNED Suppliers
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View Lastest Price from INDEX NAME NOT YET ASSIGNED manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Propargyl-PEG2-NHS ester 2512228-06-5
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-26
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