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INDEX NAME NOT YET ASSIGNED

Product Name
INDEX NAME NOT YET ASSIGNED
CAS No.
2512228-06-5
Chemical Name
INDEX NAME NOT YET ASSIGNED
Synonyms
Propargyl-PEG1-C2-CONHS ester;2,5-Dioxopyrrolidin-1-yl 3-(2-(prop-2-yn-1-yloxy)ethoxy)propanoate
CBNumber
CB79012511
Molecular Formula
C12H15NO6
Formula Weight
269.25
MOL File
2512228-06-5.mol
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INDEX NAME NOT YET ASSIGNED Property

Boiling point:
389.8±50.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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INDEX NAME NOT YET ASSIGNED Chemical Properties,Usage,Production

Biological Activity

Propargyl-PEG2-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.

INDEX NAME NOT YET ASSIGNED Preparation Products And Raw materials

Raw materials

Preparation Products

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INDEX NAME NOT YET ASSIGNED Suppliers

China 15 United States 1 Global 16
Xi'an Confluore Biological Technology Co., Ltd.
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View Lastest Price from INDEX NAME NOT YET ASSIGNED manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG2-NHS ester 2512228-06-5
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-26

2512228-06-5, INDEX NAME NOT YET ASSIGNEDRelated Search:

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  • 2,5-Dioxopyrrolidin-1-yl 3-(2-(prop-2-yn-1-yloxy)ethoxy)propanoate
  • Propargyl-PEG1-C2-CONHS ester
  • 2512228-06-5