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SERGLIFLOZIN

Product Name
SERGLIFLOZIN
CAS No.
408504-26-7
Chemical Name
SERGLIFLOZIN
Synonyms
KGT1251;GW869682;KGT-1251;GW869682X;GW-869682;GW-869682X;SERGLIFLOZIN;Sergliflozin etabonate;QLXKHBNJTPICNF-QMCAAQAGSA-N;Sergliflozin etabonate, 10 mM in DMSO
CBNumber
CB81011753
Molecular Formula
C23H28O9
Formula Weight
448.46
MOL File
408504-26-7.mol
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SERGLIFLOZIN Property

Boiling point:
611.5±55.0 °C(Predicted)
Density 
1.312
pka
12.74±0.70(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FM152924
Product name
2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
Packaging
2mg
Price
$54
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM152924
Product name
2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
Packaging
5mg
Price
$107
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM152924
Product name
2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
Packaging
10mg
Price
$186
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM152924
Product name
2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
Packaging
25mg
Price
$372
Updated
2021/12/16
AK Scientific
Product number
3382CR
Product name
Sergliflozinetabonate
Packaging
25mg
Price
$552
Updated
2021/12/16
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SERGLIFLOZIN Chemical Properties,Usage,Production

Uses

Treatment of type 2 diabetes.

Definition

ChEBI: Sergliflozin etabonate is a glycoside.

in vivo

Sergliflozin etabonate (1, 3, 10, 30 mg/kg; oral; once) significantly reduces non-fasting blood glucose levels in KK-Ay mice in a dose-dependent manner[1].
Sergliflozin etabonate (1.7, 8.4, 45.7 mg/kg in the 0.001, 0.005, and 0.025% sergliflozin etabonate; fed; daily for 9 weeks) reduces non-fasting blood glucose level and decreases triglyceride content in the liver in a dose-dependent manner in KK-Ay mice[1].

Animal Model:14 weeks, Female KK-Ay mice[1]
Dosage:1, 3, 10, 30 mg/kg
Administration:Oral; once
Result:Significantly reduced non-fasting blood glucose level with the reduction in blood glucose level at 2 h post dosing in the 1 mg/kg group, 3 mg/kg group, 10 mg/kg group, and 30 mg/kg group was 12, 15, 28, and 39%, respectively.
Animal Model:4 weeks, Female KK-Ay mice[1]
Dosage:1.7, 8.4, 45.7 mg/kg in the 0.001, 0.005, and 0.025% sergliflozin etabonate
Administration:Fed, daily for 9 weeks
Result:Reduced non-fasting blood glucose level and decreased triglyceride content in the liver in a dose-dependent manner in diabetic control KK-Ay mice.

IC 50

SGLT2

SERGLIFLOZIN Preparation Products And Raw materials

Raw materials

Preparation Products

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SERGLIFLOZIN Suppliers

China 18 Germany 1 India 1 United Kingdom 1 United States 4 Global 25
Shanghai Boyle Chemical Co., Ltd.
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021-50182298 021-50180596
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+86-21-57758967
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sales@boylechem.com
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China
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ZHIWE CHEMTECH CO LTD
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021-20221225 13917446399
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QQ:115820162
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zwchem@163.com
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China
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Chembest Research Laboratories Limited
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+86-21-20908456
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021-58180499
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sales@BioChemBest.com
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China
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6003
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
Email
info@chemlin.com.cn
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China
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16077
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Beijing Yisiyan Technology Research Center
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010-56645598 13366904824
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01062230033
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bjkaida@163.com
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China
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AN PharmaTech Co Ltd
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86(21)68097365
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86(21)33321566
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sales@anpharma.net
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China
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Chemleader Biomedical Co., Limited.
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021-58180488
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021-58180499
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sales@MedChemLeader.com
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China
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Hubei Jusheng Technology Co.,Ltd.
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18871490254
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027-59599243
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linda@hubeijusheng.com
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CHINA
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CONIER CHEM AND PHARMA LIMITED
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+8618523575427
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sales@conier.com
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China
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49975
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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Suzhou Meishi Biotechnology Co., Ltd.
Tel
1173954148q
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meishipharma@126.com
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China
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Shanghai Yifei Biotechnology Co. , Ltd.
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021-65675885 18964387627
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customer_service@efebio.com
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China
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11973
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Sangon Biotech (Shanghai) Co.,Ltd.
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400-821-026
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Sales@sangon.com
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China
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6710
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Biosynth Biological Technology (Suzhou) Co Ltd
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51288865780
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sales@biosynth.com
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China
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ATK CHEMICAL COMPANY LIMITED
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+undefined-21-51877795
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+86 21 5161 9052/ 5187 7796
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ivan@atkchemical.com
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33024
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DAYANG CHEM (HANGZHOU) CO.,LTD
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+86-88938639 +86-17705817739
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info@dycnchem.com
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China
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Absin Bioscience Inc.
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chenjw@absin.cn
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Proteintech China
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Proteintech-CN@ptglab.com
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408504-26-7, SERGLIFLOZINRelated Search:

TOFOGLIFLOZIN Dapagliflozin Ertugliflozin L-pyroglutamic acid Empagliflozin D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- Tofogliflozin 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone Acetoxy Empagliflozin Canagliflozin PHENYL-BETA-D-GLUCOPYRANOSIDE

  • QLXKHBNJTPICNF-QMCAAQAGSA-N
  • SERGLIFLOZIN
  • 2-[(4-Methoxyphenyl)methyl]phenyl-beta-D-glucopyranoside-6-(ethyl carbonate)
  • Sergliflozin etabonate
  • 2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
  • ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[(4-methoxyphenyl)methyl]phenoxy]oxan-2-yl]methyl carbonate
  • β-D-Glucopyranoside,2-[(4-methoxyphenyl)methyl]phenyl,6-(ethyl carbonate)
  • GW869682
  • GW-869682
  • GW869682X
  • GW-869682X
  • KGT1251
  • KGT-1251
  • Sergliflozin etabonate, 10 mM in DMSO
  • 408504-26-7
  • C23H28O9