Ertugliflozin L-pyroglutamic acid

Product Name: Ertugliflozin L-pyroglutamic acid
CAS No.: 1210344-83-4
Chemical Name: Ertugliflozin L-pyroglutamic acid
Synonyms: Pidolate;ERTUGLIFLOZIN PIDOLATE;Gliadine L- pyroglutamate;L-pyroglutamate atogliflozin;PF-04971729 L-pyroglutamic acid;Ertugliflozin L-pyroglutamic acid;Ertugliflozin L-pyroglutamic Acid (1:1);Ertugliflozin L-pyroglutamic acid Impurity;Ertugliflozin L-pyroglutamic acid, 10 mM in DMSO;PF-04971729 ((S)-5-oxopyrrolidine-2-carboxylic acid)
CBNumber: CB73159894
Molecular Formula: C27H32ClNO10
Formula Weight: 566
MOL File: 1210344-83-4.mol

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Ertugliflozin L-pyroglutamic acid Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: DMSO: ≥ 125 mg/mL (220.85 mM)
form: Solid
color: White to off-white
InChI: InChI=1/C22H25ClO7.C5H7NO3/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27)18(25)19(26)21(11-24,30-22)12-29-22;7-4-2-1-3(6-4)5(8)9/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3;3H,1-2H2,(H,6,7)(H,8,9)/t18-,19-,20+,21-,22-;3-/s3
InChIKey: YHIUPZFKHZTLSH-NCRAORDPNA-N
SMILES: C([C@@H]1CCC(=O)N1)(=O)O.O[C@@H]1[C@H]([C@H](O)[C@]2(CO)CO[C@@]1(C1C=CC(Cl)=C(CC3C=CC(OCC)=CC=3)C=1)O2)O |&1:1,10,11,12,14,19,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: E635095
Product name: ErtugliflozinL-pyroglutamicAcid(1:1)
Packaging: 1mg
Price: $160
Updated: 2021/12/16

ChemScene

Product number: CS-0083708
Product name: ErtugliflozinL-pyroglutamicacid
Purity: 99.98%
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-0083708
Product name: ErtugliflozinL-pyroglutamicacid
Purity: 99.98%
Packaging: 10mg
Price: $70
Updated: 2021/12/16

ChemScene

Product number: CS-0083708
Product name: ErtugliflozinL-pyroglutamicacid
Purity: 99.98%
Packaging: 50mg
Price: $120
Updated: 2021/12/16

AK Scientific

Product number: 3333DN
Product name: ErtugliflozinL-pyroglutamicacid
Packaging: 5mg
Price: $122
Updated: 2021/12/16

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Ertugliflozin L-pyroglutamic acid Chemical Properties,Usage,Production

Description

Ertugliflozin L-pyroglutamic acid is a potent, selective, orally active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor with an IC50 value of 0.877 nM for h-SGLT2.It is the main active ingredient in the tablet ertugliflozin. It is the main active ingredient of ertugliflozin tablets. It is used as an adjunctive therapy for type 2 diabetes.

Chemical Properties

Ertugliflozin L-pyroglutamic acid is a white to off-white powder, soluble in ethanol and acetone, slightly soluble in ethyl acetate and acetonitrile, and very slightly soluble in water.

Uses

Ertugliflozin L-pyroglutamic Acid is a reagent in the synthesis of Ertugliflozin (1210344-57-2) a sodium/glucose cotransporter 2 (SGLT2) inhibitor used to treat type 2 diabetes.

brand name

STEGLATRO

in vivo

Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) reveals a concentration-dependent glucosuria after oral administration to rats^[3].

IC 50

SGLT2

Ertugliflozin L-pyroglutamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Ertugliflozin L-pyroglutamic acid Suppliers

China 140 India 5 United States 3 Global 148

Shanghai Pansopharm Technology Co., Ltd.

Tel: 021-20962833 15316628753
Fax: 021-2096-2832
Email: sales@pansopharm.com
Country: China
ProdList: 724
Advantage: 60

DoEasy Pharma Co., Ltd.

Tel: 0571-0571-28806358 15397199029
Fax: 0571-89057225
Email: songxy@doepharma.com
Country: China
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Cangzhou Enke Pharma-tech Co., Ltd.

Tel: 0317-5296180 15533709196
Fax: 0317-5106596
Email: sale@enkepharma.com
Country: China
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Wuhan Jingkangen Biomedical Technology Co., Ltd

Tel: 13720134139 086-15871494362 13720134139
Email: orders@jknbiochem.com
Country: China
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Hangzhou Copiore Chemical Co., Ltd.

Tel: 0571-56501939;0571-56076030 13757145729
Fax: 0571-56501939
Email: sales@copiore.com
Country: China
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Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 021-50929289 18616309303
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Anhui Lianchuang Biological Medicine Co.,Ltd

Tel: 0551-68779238 18056025720
Email: sales3@lcywhx.com
Country: China
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Beijing Yisiyan Technology Research Center

Tel: 010-56645598 13366904824
Fax: 01062230033
Email: bjkaida@163.com
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Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
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Valiant Co., Ltd.

Tel: 0535-6101880
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Email: liutao@valiant-cn.com
Country: China
ProdList: 292
Advantage: 60

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View Lastest Price from Ertugliflozin L-pyroglutamic acid manufacturers

Wuhan JiyunZen Tech Co., Ltd.

Product: Ertugliflozin L-pyroglutamic acid 1210344-83-4
Price: US $5.00-0.50/KG
Min. Order: 1KG
Purity: 99% hplc
Supply Ability: 500TONS
Release date: 2025-06-05

Watson Biotechnology Co.,Ltd

Product: Ertugliflozin L-pyroglutamic acid 1210344-83-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20MT
Release date: 2024-08-22

Wuhan Fortuna Chemical Co.,Ltd

Product: Ertugliflozin L-pyroglutamic acid 1210344-83-4
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 50kg
Release date: 2024-08-22

1210344-83-4, Ertugliflozin L-pyroglutamic acidRelated Search:

Reboxetine ReMogliflozin etabonate TOFOGLIFLOZIN Dapagliflozin SERGLIFLOZIN Empagliflozin D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- Tofogliflozin 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone Acetoxy Empagliflozin Canagliflozin

PF-04971729 L-pyroglutamic acid

Ertugliflozin L-pyroglutamic Acid (1:1)

ERTUGLIFLOZIN PIDOLATE

Pidolate

PF-04971729 ((S)-5-oxopyrrolidine-2-carboxylic acid)

(1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol (1:1) compound with (S)-5-oxopyrrolidine-2-carboxylic acid

(S)-5-Oxopyrrolidine-2-carboxylic acid compound with (1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol (1:1)

Gliadine L- pyroglutamate

Ertugliflozin L-pyroglutamic acid

SGLT,inhibit,Ertugliflozin L-pyroglutamic acid,Sodium-dependent glucose cotransporters,Inhibitor,Ertugliflozin L pyroglutamic acid,Ertugliflozin Lpyroglutamic acid

L-pyroglutamate atogliflozin

Ertugliflozin L-pyroglutamic acid Impurity

Ertugliflozin L-pyroglutamic acid, 10 mM in DMSO

1210344-83-4