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Ertugliflozin L-pyroglutamic acid

Product Name
Ertugliflozin L-pyroglutamic acid
CAS No.
1210344-83-4
Chemical Name
Ertugliflozin L-pyroglutamic acid
Synonyms
Pidolate;ERTUGLIFLOZIN PIDOLATE;Gliadine L- pyroglutamate;L-pyroglutamate atogliflozin;PF-04971729 L-pyroglutamic acid;Ertugliflozin L-pyroglutamic acid;Ertugliflozin L-pyroglutamic Acid (1:1);Ertugliflozin L-pyroglutamic acid Impurity;PF-04971729 ((S)-5-oxopyrrolidine-2-carboxylic acid);SGLT,inhibit,Ertugliflozin L-pyroglutamic acid,Sodium-dependent glucose cotransporters,Inhibitor,Ertugliflozin L pyroglutamic acid,Ertugliflozin Lpyroglutamic acid
CBNumber
CB73159894
Molecular Formula
C27H32ClNO10
Formula Weight
566
MOL File
1210344-83-4.mol
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Ertugliflozin L-pyroglutamic acid Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO: ≥ 125 mg/mL (220.85 mM)
form 
Solid
color 
White to off-white
InChI
InChI=1/C22H25ClO7.C5H7NO3/c1-2-28-16-6-3-13(4-7-16)9-14-10-15(5-8-17(14)23)22-20(27)18(25)19(26)21(11-24,30-22)12-29-22;7-4-2-1-3(6-4)5(8)9/h3-8,10,18-20,24-27H,2,9,11-12H2,1H3;3H,1-2H2,(H,6,7)(H,8,9)/t18-,19-,20+,21-,22-;3-/s3
InChIKey
YHIUPZFKHZTLSH-NCRAORDPNA-N
SMILES
C([C@@H]1CCC(=O)N1)(=O)O.O[C@@H]1[C@H]([C@H](O)[C@]2(CO)CO[C@@]1(C1C=CC(Cl)=C(CC3C=CC(OCC)=CC=3)C=1)O2)O |&1:1,10,11,12,14,19,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
E635095
Product name
ErtugliflozinL-pyroglutamicAcid(1:1)
Packaging
1mg
Price
$160
Updated
2021/12/16
ChemScene
Product number
CS-0083708
Product name
ErtugliflozinL-pyroglutamicacid
Purity
99.98%
Packaging
5mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-0083708
Product name
ErtugliflozinL-pyroglutamicacid
Purity
99.98%
Packaging
10mg
Price
$70
Updated
2021/12/16
ChemScene
Product number
CS-0083708
Product name
ErtugliflozinL-pyroglutamicacid
Purity
99.98%
Packaging
50mg
Price
$120
Updated
2021/12/16
AK Scientific
Product number
3333DN
Product name
ErtugliflozinL-pyroglutamicacid
Packaging
5mg
Price
$122
Updated
2021/12/16
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Ertugliflozin L-pyroglutamic acid Chemical Properties,Usage,Production

Description

Ertugliflozin L-pyroglutamic acid is a potent, selective, orally active sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor with an IC50 value of 0.877 nM for h-SGLT2.It is the main active ingredient in the tablet ertugliflozin. It is the main active ingredient of ertugliflozin tablets. It is used as an adjunctive therapy for type 2 diabetes.

Chemical Properties

Ertugliflozin L-pyroglutamic acid is a white to off-white powder, soluble in ethanol and acetone, slightly soluble in ethyl acetate and acetonitrile, and very slightly soluble in water.

Uses

Ertugliflozin L-pyroglutamic Acid is a reagent in the synthesis of Ertugliflozin (1210344-57-2) a sodium/glucose cotransporter 2 (SGLT2) inhibitor used to treat type 2 diabetes.

brand name

STEGLATRO

Ertugliflozin L-pyroglutamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ertugliflozin L-pyroglutamic acid manufacturers

Watson Biotechnology Co.,Ltd
Product
Ertugliflozin L-pyroglutamic acid 1210344-83-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20MT
Release date
2024-08-22
Wuhan Fortuna Chemical Co.,Ltd
Product
Ertugliflozin L-pyroglutamic acid 1210344-83-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50kg
Release date
2024-08-22
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Ertugliflozin L-Pyroglutamic Acid 1210344-83-4
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2024-09-05

1210344-83-4, Ertugliflozin L-pyroglutamic acidRelated Search:

Reboxetine ReMogliflozin etabonate TOFOGLIFLOZIN Dapagliflozin SERGLIFLOZIN Empagliflozin D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- Tofogliflozin 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone Acetoxy Empagliflozin Canagliflozin

  • PF-04971729 L-pyroglutamic acid
  • Ertugliflozin L-pyroglutamic Acid (1:1)
  • ERTUGLIFLOZIN PIDOLATE
  • Pidolate
  • PF-04971729 ((S)-5-oxopyrrolidine-2-carboxylic acid)
  • (1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol (1:1) compound with (S)-5-oxopyrrolidine-2-carboxylic acid
  • (S)-5-Oxopyrrolidine-2-carboxylic acid compound with (1S,2S,3S,4R,5S)-5-(4-chloro-3-(4-ethoxybenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol (1:1)
  • Gliadine L- pyroglutamate
  • Ertugliflozin L-pyroglutamic acid
  • SGLT,inhibit,Ertugliflozin L-pyroglutamic acid,Sodium-dependent glucose cotransporters,Inhibitor,Ertugliflozin L pyroglutamic acid,Ertugliflozin Lpyroglutamic acid
  • L-pyroglutamate atogliflozin
  • Ertugliflozin L-pyroglutamic acid Impurity
  • 1210344-83-4