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SERGLIFLOZIN

Product Name
SERGLIFLOZIN
CAS No.
408504-26-7
Chemical Name
SERGLIFLOZIN
Synonyms
KGT1251;GW869682;KGT-1251;GW869682X;GW-869682;GW-869682X;SERGLIFLOZIN;Sergliflozin etabonate;QLXKHBNJTPICNF-QMCAAQAGSA-N;Sergliflozin etabonate, 10 mM in DMSO
CBNumber
CB81011753
Molecular Formula
C23H28O9
Formula Weight
448.46
MOL File
408504-26-7.mol
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SERGLIFLOZIN Property

Boiling point:
611.5±55.0 °C(Predicted)
Density 
1.312
pka
12.74±0.70(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FM152924
Product name
2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
Packaging
2mg
Price
$54
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM152924
Product name
2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
Packaging
5mg
Price
$107
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM152924
Product name
2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
Packaging
10mg
Price
$186
Updated
2021/12/16
Biosynth Carbosynth
Product number
FM152924
Product name
2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
Packaging
25mg
Price
$372
Updated
2021/12/16
AK Scientific
Product number
3382CR
Product name
Sergliflozinetabonate
Packaging
25mg
Price
$552
Updated
2021/12/16
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SERGLIFLOZIN Chemical Properties,Usage,Production

Uses

Treatment of type 2 diabetes.

Definition

ChEBI: Sergliflozin etabonate is a glycoside.

in vivo

Sergliflozin etabonate (1, 3, 10, 30 mg/kg; oral; once) significantly reduces non-fasting blood glucose levels in KK-Ay mice in a dose-dependent manner[1].
Sergliflozin etabonate (1.7, 8.4, 45.7 mg/kg in the 0.001, 0.005, and 0.025% sergliflozin etabonate; fed; daily for 9 weeks) reduces non-fasting blood glucose level and decreases triglyceride content in the liver in a dose-dependent manner in KK-Ay mice[1].

Animal Model:14 weeks, Female KK-Ay mice[1]
Dosage:1, 3, 10, 30 mg/kg
Administration:Oral; once
Result:Significantly reduced non-fasting blood glucose level with the reduction in blood glucose level at 2 h post dosing in the 1 mg/kg group, 3 mg/kg group, 10 mg/kg group, and 30 mg/kg group was 12, 15, 28, and 39%, respectively.
Animal Model:4 weeks, Female KK-Ay mice[1]
Dosage:1.7, 8.4, 45.7 mg/kg in the 0.001, 0.005, and 0.025% sergliflozin etabonate
Administration:Fed, daily for 9 weeks
Result:Reduced non-fasting blood glucose level and decreased triglyceride content in the liver in a dose-dependent manner in diabetic control KK-Ay mice.

IC 50

SGLT2

SERGLIFLOZIN Preparation Products And Raw materials

Raw materials

Preparation Products

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SERGLIFLOZIN Suppliers

China 18 Germany 1 India 1 United Kingdom 1 United States 4 Global 25
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
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China
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2208
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ZHIWE CHEMTECH CO LTD
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021-20221225 13917446399
Fax
QQ:115820162
Email
zwchem@163.com
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China
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617
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Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
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China
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6003
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61
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
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2123
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Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
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64
Beijing Yisiyan Technology Research Center
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010-56645598 13366904824
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01062230033
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bjkaida@163.com
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China
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1618
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AN PharmaTech Co Ltd
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86(21)68097365
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86(21)33321566
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sales@anpharma.net
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China
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4891
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Chemleader Biomedical Co., Limited.
Tel
021-58180488
Fax
021-58180499
Email
sales@MedChemLeader.com
Country
China
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1006
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
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32435
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58
Hubei Jusheng Technology Co.,Ltd.
Tel
18871490254
Fax
027-59599243
Email
linda@hubeijusheng.com
Country
CHINA
ProdList
28172
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58

408504-26-7, SERGLIFLOZINRelated Search:

TOFOGLIFLOZIN Dapagliflozin Ertugliflozin L-pyroglutamic acid Empagliflozin D-Glucitol, 1,5-dideoxy-1,5-epithio-1-C-[5-[(4-ethoxyphenyl)Methyl]-2-Methoxy-4-Methylphenyl]-, (1S)- Tofogliflozin 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone Acetoxy Empagliflozin Canagliflozin PHENYL-BETA-D-GLUCOPYRANOSIDE

  • QLXKHBNJTPICNF-QMCAAQAGSA-N
  • SERGLIFLOZIN
  • 2-[(4-Methoxyphenyl)methyl]phenyl-beta-D-glucopyranoside-6-(ethyl carbonate)
  • Sergliflozin etabonate
  • 2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-beta-D-glucopyranoside
  • ethyl [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[2-[(4-methoxyphenyl)methyl]phenoxy]oxan-2-yl]methyl carbonate
  • β-D-Glucopyranoside,2-[(4-methoxyphenyl)methyl]phenyl,6-(ethyl carbonate)
  • GW869682
  • GW-869682
  • GW869682X
  • GW-869682X
  • KGT1251
  • KGT-1251
  • Sergliflozin etabonate, 10 mM in DMSO
  • 408504-26-7
  • C23H28O9