MELPERONE

Product Name: MELPERONE
CAS No.: 3575-80-2
Chemical Name: MELPERONE
Synonyms: FG 5111;Buronil;Melperon;metylperon;Flubuperone;Melperone >Melperone,Inhibitor,inhibit;Melperone (base and/or unspecified salts);4-Fluoro-γ-(4-Methylpiperidino)butyrophenone;γ-(4-Methylpiperidino)-p-fluorobutyrophenone
CBNumber: CB81011889
Molecular Formula: C16H22FNO
Formula Weight: 263.35
MOL File: 3575-80-2.mol

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MELPERONE Property

Melting point:: 78.0 to 82.0 °C
Boiling point:: bp0.1 120-125°
Density: 1.046±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 41.67 mg/mL (158.23 mM)
pka: 9.34±0.10(Predicted)
form: powder to crystal
color: White to Light yellow to Light orange
Merck: 14,5827

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Safety

HS Code: 2933.39.3100

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H319Causes serious eye irritation

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2622
Product name: Melperone
Purity: >95.0%(GC)
Packaging: 25mg
Price: $116
Updated: 2024/03/01

TCI Chemical

Product number: M2622
Product name: Melperone
Purity: >95.0%(GC)
Packaging: 100mg
Price: $338
Updated: 2024/03/01

Chem-Impex

Product number: 38067
Product name: Melperone,95%(GC)
Purity: 95%(GC)
Packaging: 100MG
Price: $400.96
Updated: 2021/12/16

AK Scientific

Product number: E830
Product name: Melperone
Packaging: 100mg
Price: $538
Updated: 2021/12/16

Chem-Impex

Product number: 38067
Product name: Melperone,95%(GC)
Purity: 95%(GC)
Packaging: 25MG
Price: $123.2
Updated: 2021/12/16

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MELPERONE Chemical Properties,Usage,Production

Originator

Eunerpan,Nordmark,W. Germany,1965

Definition

ChEBI: 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone is an aromatic ketone.

Manufacturing Process

A solution or dispersion consisting of 20.1 g (0.1 mol) of γ-chloro-pfluorobutyrophenone, 19.8 g (0.2 mol) of 4-methylpiperidine and 0.1 g of potassium iodide in 150 ml toluene is heated in a sealed glass tube for 15 hours at 100°C to 110°C. The potassium iodide and the 4-methylpiperidine hydrochloride formed in the reaction are separated by filtration and the solvent removed from the filtrate by evaporation in vacuum on a steam bath. The residue is distilled and the fraction obtained at 120°C to 125°C and at a pressure lower than 0.1 mm Hg is collected. The base is dissolved in ether and the 4-fluoro-γ-(4-methylpiperidino)-butyrophenone precipitated as the hydrochloride. The reaction product is purified by recrystallization in ethanol/ether.
Yield 22.0 g (73% of theory). MP 209°C to 211°C.

Therapeutic Function

Neuroleptic

MELPERONE Preparation Products And Raw materials

Raw materials

Preparation Products

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MELPERONE Suppliers

Americas 1 China 29 Europe 1 India 3 Japan 1 United Kingdom 1 United States 6 Global 42

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28398
Advantage: 80

TCI Europe

Tel: 320-37350700
Fax: +32 (0)37350701
Email: sales@tcieurope.eu
Country: Europe
ProdList: 23680
Advantage: 75

TCI AMERICA

Tel: 800-4238616
Fax: +1-888-520-1075 / +1-503-283-1987
Email: sales@tciamerica.com
Country: Americas
ProdList: 23662
Advantage: 75

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9907
Advantage: 55

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 17501653713 17501653715
Email: xingui2022@126.com
Country: China
ProdList: 10033
Advantage: 58

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9798
Advantage: 50

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31557
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

3575-80-2, MELPERONERelated Search:

PIPAMPERONE DIHYDROCHLORIDE APPROX. 99 Fluspiperone SPIPERONE Haloperidol HALOPERIDOL-D4 dihydrolenperone (CARBOXYMETHYLOXIMINO)SPIPERONE, HEMIHYDRATE TRIFLUPERIDOL HCL Melperone hydrochloride N-(p-Aminophenethyl)spiperone 8-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]-1-PHENYL-1,3,8-TRIAZASPIRO[4,5]DECAN-4-ONE HYDROCHLORIDE 4-[4-(4-CHLOROPHENYL)-4-HYDROXY-1-PIPERIDINYL]-1-(4-FLUOROPHENYL)-1-BUTANONE HYDROCHLORIDE N-(P-ISOTHIOCYANATOPHENETHYL)SPIPERONE HYDROCHLORIDE HALOPERIDOL, [3H(G)]- 2'-IODOSPIPERONE, [125I]- METHYLSPIPERONE, [N-METHYL-3H] N-METHYL-8-[4-(4-FLUOROPHENYL)-4-OXOBUTYL]-1-PHENYL-1,3,8-TRIAZASPIRO-[4.5]DECAN-4-ONE HYDROCHLORIDE Pipamperone

metylperon

Melperone (base and/or unspecified salts)

1-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)-1-butanone

Melperon

1-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one

1-(4-Fluorophenyl)-4-(4-Methyl-1-piperidinyl)-1-butanone

4'-Fluoro-4-(4-Methylpiperidino)butyrophenone

4-Fluoro-γ-(4-Methylpiperidino)butyrophenone

Buronil

FG 5111

Flubuperone

γ-(4-Methylpiperidino)-p-fluorobutyrophenone

Melperone &gt

1-Butanone, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-

Melperone,Inhibitor,inhibit

3575-80-2

C16H22FNO