9-Chloroacridine

Product Name: 9-Chloroacridine
CAS No.: 1207-69-8
Chemical Name: 9-Chloroacridine
Synonyms: AURORA KA-4303;9-chloracridine;9-chloroacridone;9-CHLOROACRIDINE;Acridine, 9-chloro-;9-Chloroacridine,95%;9-CHLOROACRIDINE 95%;9-Chloroacridine, GC 95%
CBNumber: CB8106496
Molecular Formula: C13H8ClN
Formula Weight: 213.66
MOL File: 1207-69-8.mol

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9-Chloroacridine Property

Melting point:: 116-120 °C (lit.)
Boiling point:: 346.74°C (rough estimate)
Density: 1.1961 (rough estimate)
refractive index: 1.5868 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: solid
pka: 3.96±0.10(Predicted)
Appearance: Light yellow to yellow Solid
InChI: InChI=1S/C13H8ClN/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H
InChIKey: BPXINCHFOLVVSG-UHFFFAOYSA-N
SMILES: C1C2C(=NC3C(C=2Cl)=CC=CC=3)C=CC=1
CAS DataBase Reference: 1207-69-8(CAS DataBase Reference)
NIST Chemistry Reference: Acridine, 9-chloro-(1207-69-8)
EPA Substance Registry System: Acridine, 9-chloro- (1207-69-8)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36-37/39
RIDADR: UN2811
WGK Germany: 3
HS Code: 29379000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 159425
Product name: 9-Chloroacridine
Purity: 97%
Packaging: 1g
Price: $62.4
Updated: 2025/07/31

Sigma-Aldrich

Product number: 159425
Product name: 9-Chloroacridine
Purity: 97%
Packaging: 5g
Price: $278
Updated: 2025/07/31

TCI Chemical

Product number: C0392
Product name: 9-Chloroacridine
Purity: min. 95.0 %
Packaging: 1G
Price: $92
Updated: 2025/07/31

TCI Chemical

Product number: C0392
Product name: 9-Chloroacridine
Purity: min. 95.0 %
Packaging: 5G
Price: $276
Updated: 2025/07/31

TRC

Product number: C363768
Product name: 9-Chloroacridine
Packaging: 2.5g
Price: $110
Updated: 2021/12/16

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9-Chloroacridine Chemical Properties,Usage,Production

Chemical Properties

Green to brown solid

Uses

9-Chloroacridine was employed as chromogenic reagent in the spectrophotometric method for the quantitative determination of dapsone. It was also used in the synthesis of:
series of novel chalcones bearing acridine moiety attached to the amino group in their ring A
new acridine derivatives
9-phenoxyacridine and 4-phenoxyfuro[2,3-b]quinoline derivatives

Synthesis

578-95-0

1207-69-8

The general procedure for the synthesis of 9-chloroacridine from acridinone was as follows: 9-acridinone (4.01 g, 21 mmol) was dissolved in phosphoryl chloride (105 mL, 1.13 mol), a magnetic stirrer was added, and the reaction was carried out at reflux for 12 hours. Upon completion of the reaction, the reaction solution was cooled to room temperature, slowly poured into crushed ice (650 g) and the pH was adjusted to a weak base with concentrated ammonium hydroxide. The resulting light brown solid was collected by filtration, washed well with water and subsequently dried in air for 24 hours. Purification by fast column chromatography (silica gel as stationary phase, eluent was a solvent mixture of 75% hexane, 20% THF and 5% triethylamine) gave 3.97 g (89% yield) of the target product, 9-chloroacridine, as fine yellow needle-like crystals. The obtained product was confirmed to be consistent with the sample prepared by Method A by TLC, melting point determination and spectral data analysis.

References

[1] Pharmaceutical Sciences, 1997, vol. 3, # 5-6, p. 235 - 239
[2] European Journal of Inorganic Chemistry, 1999, # 3, p. 557 - 563
[3] Heterocycles, 2014, vol. 88, # 1, p. 535 - 546
[4] Patent: CN108640873, 2018, A. Location in patent: Paragraph 0022; 0023
[5] Chemical Biology and Drug Design, 2017, vol. 90, # 5, p. 926 - 935

9-Chloroacridine Preparation Products And Raw materials

Raw materials

Preparation Products

Amsacrine 9-AMINOACRIDINE

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9-Chloroacridine Suppliers

Austria 1 China 197 Europe 1 Germany 2 India 9 Switzerland 1 United Kingdom 2 United States 15 Global 228

Zhengzhou Yuanli Biological Technology Co., Ltd.

Tel: 0371-67897870 18339906974
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J & K SCIENTIFIC LTD.

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INTATRADE GmbH

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Beijing HwrkChemical Technology Co., Ltd

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Energy Chemical

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Capot Chemical Co., Ltd

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JinYan Chemicals(ShangHai) Co.,Ltd.

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Jia Xing Isenchem Co.,Ltd

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ShengXiong Biological Technology Development Co., Ltd.

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Shanghai Hanhong Scientific Co.,Ltd.

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View Lastest Price from 9-Chloroacridine manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd

Product: 9-Chloroacridine 1207-69-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: Customise
Release date: 2025-09-18

Hebei Chuanghai Biotechnology Co., Ltd

Product: 9-Chloroacridine 1207-69-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-04

Shanghai UCHEM Inc.

Product: 9-Chloroacridine 1207-69-8
Price: US $44.00-296.00/g
Min. Order: 5g
Purity: 0.98
Supply Ability: 25kg
Release date: 2023-12-08

1207-69-8, 9-ChloroacridineRelated Search:

Basic Orange 14 6,9-DIAMINO-2-ETHOXYACRIDINE LACTATE Amsacrine hydrochloride 2-ETHOXY-6,9-DIAMINOACRIDINE Quinacridone 2,9-DICHLOROACRIDINE 6,9-Dichloro-2-methoxyacridine 2-Methoxy-6-chloroacridine-9-amine 10-Butyl-2-chloroacridine-9(10H)-one Acridine 2,7-BIS(ALLOXYCARBONYLAMINO)-9-CHLOROACRIDINE 9-CHLORO-2-METHOXYACRIDINE 1,2,3,4-tetrahydro-9-chloroacridin 9-Chloroacridine 2-ETHOXY-6-NITRO-9-CHLORO-ACRIDINE 3,9-DICHLORO-7-METHOXY-2-NITROACRIDINE 9-amino-6-chloroacridine-2-phosphate 1-NITRO-4-CHLOROACRIDINE

9-CHLOROACRIDINE

AURORA KA-4303

9-Chloroacridine, GC 95%

9-CHLOROACRIDINE 95%

9-Chloroacridine,95%

9-chloroacridone

Acridine, 9-chloro-

9-chloracridine

1207-69-8

C13H8ClN

Acridines

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Heterocyclic Building Blocks

Acridines

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

AcridinesHeterocyclic Building Blocks

Pharmaceutical material and intermeidates

1207-69-8