9-Chloroacridine
- Product Name
- 9-Chloroacridine
- CAS No.
- 1207-69-8
- Chemical Name
- 9-Chloroacridine
- Synonyms
- AURORA KA-4303;9-chloracridine;9-chloroacridone;9-CHLOROACRIDINE;Acridine, 9-chloro-;9-Chloroacridine,95%;9-CHLOROACRIDINE 95%;9-Chloroacridine, GC 95%
- CBNumber
- CB8106496
- Molecular Formula
- C13H8ClN
- Formula Weight
- 213.66
- MOL File
- 1207-69-8.mol
9-Chloroacridine Property
- Melting point:
- 116-120 °C (lit.)
- Boiling point:
- 346.74°C (rough estimate)
- Density
- 1.1961 (rough estimate)
- refractive index
- 1.5868 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- solid
- pka
- 3.96±0.10(Predicted)
- Appearance
- Light yellow to yellow Solid
- InChI
- InChI=1S/C13H8ClN/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H
- InChIKey
- BPXINCHFOLVVSG-UHFFFAOYSA-N
- SMILES
- C1C2C(=NC3C(C=2Cl)=CC=CC=3)C=CC=1
- CAS DataBase Reference
- 1207-69-8(CAS DataBase Reference)
- NIST Chemistry Reference
- Acridine, 9-chloro-(1207-69-8)
- EPA Substance Registry System
- Acridine, 9-chloro- (1207-69-8)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36-37/39
- RIDADR
- UN2811
- WGK Germany
- 3
- HS Code
- 29379000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 159425
- Product name
- 9-Chloroacridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $62.4
- Updated
- 2025/07/31
- Product number
- 159425
- Product name
- 9-Chloroacridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $278
- Updated
- 2025/07/31
- Product number
- C0392
- Product name
- 9-Chloroacridine
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $92
- Updated
- 2025/07/31
- Product number
- C0392
- Product name
- 9-Chloroacridine
- Purity
- min. 95.0 %
- Packaging
- 5G
- Price
- $276
- Updated
- 2025/07/31
- Product number
- C363768
- Product name
- 9-Chloroacridine
- Packaging
- 2.5g
- Price
- $110
- Updated
- 2021/12/16
9-Chloroacridine Chemical Properties,Usage,Production
Chemical Properties
Green to brown solid
Uses
9-Chloroacridine was employed as chromogenic reagent in the spectrophotometric method for the quantitative determination of dapsone. It was also used in the synthesis of:
series of novel chalcones bearing acridine moiety attached to the amino group in their ring A
new acridine derivatives
9-phenoxyacridine and 4-phenoxyfuro[2,3-b]quinoline derivatives
Synthesis
578-95-0
1207-69-8
The general procedure for the synthesis of 9-chloroacridine from acridinone was as follows: 9-acridinone (4.01 g, 21 mmol) was dissolved in phosphoryl chloride (105 mL, 1.13 mol), a magnetic stirrer was added, and the reaction was carried out at reflux for 12 hours. Upon completion of the reaction, the reaction solution was cooled to room temperature, slowly poured into crushed ice (650 g) and the pH was adjusted to a weak base with concentrated ammonium hydroxide. The resulting light brown solid was collected by filtration, washed well with water and subsequently dried in air for 24 hours. Purification by fast column chromatography (silica gel as stationary phase, eluent was a solvent mixture of 75% hexane, 20% THF and 5% triethylamine) gave 3.97 g (89% yield) of the target product, 9-chloroacridine, as fine yellow needle-like crystals. The obtained product was confirmed to be consistent with the sample prepared by Method A by TLC, melting point determination and spectral data analysis.
References
[1] Pharmaceutical Sciences, 1997, vol. 3, # 5-6, p. 235 - 239
[2] European Journal of Inorganic Chemistry, 1999, # 3, p. 557 - 563
[3] Heterocycles, 2014, vol. 88, # 1, p. 535 - 546
[4] Patent: CN108640873, 2018, A. Location in patent: Paragraph 0022; 0023
[5] Chemical Biology and Drug Design, 2017, vol. 90, # 5, p. 926 - 935
9-Chloroacridine Preparation Products And Raw materials
Raw materials
Preparation Products
9-Chloroacridine Suppliers
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- --
- Fax
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- sales@chemos-group.com
- Country
- Germany
- ProdList
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View Lastest Price from 9-Chloroacridine manufacturers
- Product
- 9-Chloroacridine 1207-69-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-09-18
- Product
- 9-Chloroacridine 1207-69-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-04
- Product
- 9-Chloroacridine 1207-69-8
- Price
- US $44.00-296.00/g
- Min. Order
- 5g
- Purity
- 0.98
- Supply Ability
- 25kg
- Release date
- 2023-12-08