1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE

Product Name: 1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE
CAS No.: 65513-72-6
Chemical Name: 1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE
Synonyms: GlafenineHCl;Glafenin hydrochloride;GLAFENINE HYDROCHLORIDE;1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE;inhibit,Glafenine Hydrochloride,Glafenine,Glafenin,Inhibitor;2,3-Dihydroxypropyl 2-((7-chloroquinolin-4-yl)amino)benzoate hydrochloride
CBNumber: CB8107352
Molecular Formula: C19H18Cl2N2O4
Formula Weight: 409.26
MOL File: 65513-72-6.mol

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1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE Property

storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO : ≥ 60 mg/mL (146.61 mM)
form: Solid
color: Light yellow to yellow
Major Application: forensics and toxicology
pharmaceutical (small molecule)
InChI: 1S/C19H17ClN2O4.ClH/c20-12-5-6-14-17(7-8-21-18(14)9-12)22-16-4-2-1-3-15(16)19(25)26-11-13(24)10-23;/h1-9,13,23-24H,10-11H2,(H,21,22);1H
InChIKey: CEUMONXVSJOJIH-UHFFFAOYSA-N
SMILES: Cl.OCC(O)COC(=O)c1ccccc1Nc2ccnc3cc(Cl)ccc23

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 36
WGK Germany: 3
RTECS: CB2687000
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G7020
Product name: Glafenine hydrochloride
Purity: analytical standard
Packaging: 1g
Price: $19.8
Updated: 2022/05/15

Ambeed

Product number: A177288
Product name: GlafenineHCl
Purity: 97%
Packaging: 100mg
Price: $46
Updated: 2021/12/16

CSNpharm

Product number: CSN21978
Product name: GlafenineHCl
Packaging: 100mg
Price: $51
Updated: 2021/12/16

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1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Analgesic

in vivo

Glafenine injection (25 mg/kg i.v.) shows enhanced BLI signal in mice with an average of 2.9-fold signal enhancement over the control. Glafenine causes increases in BLI signal of up to 11.6- and 17.4-fold in two separate HEK293/ABCG2/fLuc xenografts in the same mouse compared to the signals generated by those xenografts immediately before injection^[1]. Incubating polarized CFBE41o^- monolayers and intestines isolated from mutant CFTR mice with glafenine increases the short-circuit current response to forskolin and genistein. Treatment with glafenine also partially restores total salivary secretion^[2]. Glafenine-treated zebrafish shows evidence of endoplasmic reticulum and mitochondrial stress, with disrupted intestinal architecture and halted cell stress responses, alongside accumulation of apoptotic intestinal epithelial cells in the lumen^[4].

1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE Suppliers

China 26 Switzerland 1 United Kingdom 1 United States 8 Global 36

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25363
Advantage: 65

MedChemexpress LLC

Tel: 021-58955995
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Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
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Country: China
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
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Country: China
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Advantage: 60

UHN Shanghai Research & Development Co., Ltd.

Tel: 021-58958002 18930822973
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Guangzhou Tomums Life Science Co., Ltd.

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Country: China
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Advantage: 58

Jiangsu aikang biomedical research and development co., LTD

Tel: 025-58859352 13155353615
Email: qzhang@aikonchem.com
Country: China
ProdList: 15525
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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Absin Bioscience Inc.

Tel: 021-38015121 18438616290
Email: lanwu@univ-bio.com
Country: China
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Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
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Country: China
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65513-72-6, 1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDERelated Search:

Pyridine hydrochloride Trimethylamine hydrochloride Triethylamine hydrochloride Methylamine hydrochloride Amfepramone hydrochloride

GlafenineHCl

Glafenin hydrochloride

GLAFENINE HYDROCHLORIDE

1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE

2,3-Dihydroxypropyl 2-((7-chloroquinolin-4-yl)amino)benzoate hydrochloride

inhibit,Glafenine Hydrochloride,Glafenine,Glafenin,Inhibitor

65513-72-6

3820-57-6

C19H17ClN2O4HCl

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