ChemicalBook > CAS DataBase List > Sinitrodil

Sinitrodil

Product Name
Sinitrodil
CAS No.
143248-63-9
Chemical Name
Sinitrodil
Synonyms
ITF296;ITF-296;ITF 296;Sinitrodil;Sinitrodil, 10 mM in DMSO
CBNumber
CB81117729
Molecular Formula
C10H10N2O5
Formula Weight
238.198
MOL File
143248-63-9.mol
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
API0025263
Product name
SINITRODIL
Purity
95.00%
Packaging
5MG
Price
$500.03
Updated
2021/12/16
More
Less

Sinitrodil Chemical Properties,Usage,Production

Uses

Sinitrodil (ITF 296) is an orally active organic nitrate with anti-ischaemic effect. Sinitrodil can be used for acute and chronic heart diseases research[1][2].

in vivo

1.19
Pharmacokinetic parameters of Sinitrodil in rats[2]
RouteParameterValue
IV (1 mg/kg)CL (L/h/kg)2.7
AUC (μg h/mL)0.37
T1/2 (h)3.85
PO (5 mg/kg)Tmax (h)0.17
T1/2 (h)1.95
Cmax (μg/mL)2.099
CL (L/h/kg)2.69
AUC (μg h/mL)1.364

References

[1] Monzani MV, et al. Pharmacokinetics of ITF 296 (Sinitrodil) a novel organic nitrate, in healthy volunteers. Eur J Pharm Sci. 1999 Feb;7(3):179-84. DOI:10.1016/s0928-0987(98)00026-8
[2] Monzani MV, et al. Pharmacokinetic Profile of ITF 296 in Rats and Dogs. Journal of Cardiovascular Pharmacology 26:p S67-71,

Sinitrodil Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Sinitrodil Suppliers

China 8 United Kingdom 1 United States 4 Global 13
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42

143248-63-9, SinitrodilRelated Search:

Fasudil hydrochloride FASUDIL 6-[[3-[4-(2-Methoxyphenyl)-1-piperazinyl]propyl]amino]-1,3-dimethyluracil Diltiazem N-(2-HYDROXYETHYL)SALICYLAMIDE, 98 Sinitrodil Aminoethyl nitrate

  • Sinitrodil
  • ITF 296
  • ITF296
  • ITF-296
  • Sinitrodil, 10 mM in DMSO
  • 143248-63-9