ChemicalBook > CAS DataBase List > 3-Nitrophthalic anhydride

3-Nitrophthalic anhydride

Product Name
3-Nitrophthalic anhydride
CAS No.
641-70-3
Chemical Name
3-Nitrophthalic anhydride
Synonyms
1,3-Isobenzofurandione, 4-nitro-;3-Nitrophthalic Acid Anhydride;4-NITRO-ISOBENZOFURAN-1,3-DIONE;NSC 4134;NSC 27006;3-NitrophthaL;Pomalidomide INT;Apremilast Impurity 90;Pomadomide impurity 36.;Pomalidomide Impurity 36
CBNumber
CB8116378
Molecular Formula
C8H3NO5
Formula Weight
193.11
MOL File
641-70-3.mol
More
Less

3-Nitrophthalic anhydride Property

Melting point:
163-165 °C (lit.)
Boiling point:
329.3°C (rough estimate)
Density 
1.6392 (rough estimate)
refractive index 
1.4700 (estimate)
storage temp. 
Store below +30°C.
form 
Crystalline Powder
color 
Beige to yellow
Water Solubility 
MAY DECOMPOSE
Sensitive 
Moisture Sensitive
BRN 
179963
CAS DataBase Reference
641-70-3(CAS DataBase Reference)
NIST Chemistry Reference
3-Nitrophthalic anhydride(641-70-3)
EPA Substance Registry System
1,3-Isobenzofurandione, 4-nitro- (641-70-3)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
10-21
TSCA 
Yes
HS Code 
29173980
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.20903
Product name
3-Nitrophthalic anhydride
Purity
for synthesis
Packaging
25g
Price
$87.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20903
Product name
3-Nitrophthalic anhydride
Purity
for synthesis
Packaging
100g
Price
$164
Updated
2024/03/01
Sigma-Aldrich
Product number
156884
Product name
3-Nitrophthalic anhydride
Purity
98%
Packaging
5g
Price
$76.2
Updated
2024/03/01
Sigma-Aldrich
Product number
156884
Product name
3-Nitrophthalic anhydride
Purity
98%
Packaging
25g
Price
$148.8
Updated
2024/03/01
TCI Chemical
Product number
N0245
Product name
3-Nitrophthalic Anhydride
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$33
Updated
2024/03/01
More
Less

3-Nitrophthalic anhydride Chemical Properties,Usage,Production

Chemical Properties

Beige to yellow crystalline powder

Uses

An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472). Reactions with aminoquinazolinones yield phthalimidoquinazolinones.

Uses

4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones.

Preparation

3-Nitrophthalic anhydride can be prepared by heating 3-nitrophthalic acid under various conditions and by the action of acetic anhydride, essentially as in the procedure described. The direct nitration of phthalic anhydride yields 3-nitrophthalic anhydride together with the isomeric 4-nitro compound.

Purification Methods

Crystallise it from *C6H6, *C6H6/pet ether, Me2CO, AcOH, or Ac2O (m 164-165o). Dry it at 100o. [Beilstein 17 III/IV 6149, 17/11 V 266.]

3-Nitrophthalic anhydride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-Nitrophthalic anhydride Suppliers

Novachemistry
Tel
44-20819178-90 02081917890
Fax
(0)2080432064
Email
info@novachemistry.com
Country
United Kingdom
ProdList
4381
Advantage
58
Melrob Ltd (part of Nordmann)
Tel
--
Fax
--
Email
nquiries@melrob.com
Country
United Kingdom
ProdList
3065
Advantage
58
Fisher Scientific Uk Ltd.
Tel
--
Fax
--
Email
.international@thermofisher.com
Country
United Kingdom
ProdList
2932
Advantage
58
Molekula Limited
Tel
--
Fax
--
Email
o@molekula.com
Country
United Kingdom
ProdList
6127
Advantage
58
Apollo Scientific Ltd
Tel
--
Fax
--
Email
ales@apo
Country
United Kingdom
ProdList
4521
Advantage
58
Manchester Organics
Tel
--
Fax
--
Email
info@manchesterorganics.com
Country
United Kingdom
ProdList
6834
Advantage
67
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
Apin Chemicals Limited (UK)
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6184
Advantage
60
Leancare Ltd.
Tel
--
Fax
--
Email
enquiry@leancare.co.uk
Country
United Kingdom
ProdList
6446
Advantage
42
CARBONE SCIENTIFIC CO.,LTD
Tel
--
Fax
--
Email
sales@carbonesci.com
Country
United Kingdom
ProdList
6666
Advantage
30
Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46
MOLEKULA Ltd.
Tel
--
Fax
--
Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
Fluorochem Ltd
Tel
--
Fax
--
Email
vernam@fluorochem.co.uk
Country
United Kingdom
ProdList
6375
Advantage
65
UK GREEN SCIENTIFIC CO.,LIMITED
Tel
--
Fax
--
Email
sales@gs-chem.com
Country
United Kingdom
ProdList
6098
Advantage
47
ARIAC - Armenian Institute of Applied Chemistry
Tel
--
Fax
--
Email
ariac@web.am
Country
United Kingdom
ProdList
2466
Advantage
46
Apin Chemicals Ltd.
Tel
--
Fax
--
Email
info@apinchemicals.com
Country
United Kingdom
ProdList
6807
Advantage
42
VWR International
Tel
--
Fax
--
Email
solutions@vwr.com
Country
United Kingdom
ProdList
6548
Advantage
82
More
Less

View Lastest Price from 3-Nitrophthalic anhydride manufacturers

Asia Chem I and E (Jiangsu) Co Ltd
Product
3-Nitrophthalic anhydride 641-70-3
Price
US $62.79/Kg/Drum
Min. Order
25Kg/Drum
Purity
98.00%HPLC
Supply Ability
8.8tons/month
Release date
2021-09-23
Hebei Chuanghai Biotechnology Co,.LTD
Product
3-Nitrophthalic anhydride 641-70-3
Price
US $10.70/kg
Min. Order
10kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23
Hebei Kangcang new material Technology Co., LTD
Product
3-Nitrophthalic anhydride 641-70-3
Price
US $9.00-80.00/g
Min. Order
10g
Purity
min99%
Supply Ability
10 tons
Release date
2024-03-26

641-70-3, 3-Nitrophthalic anhydrideRelated Search:


  • 1,3-Isobenzofurandione, 4-nitro-
  • 1,3-Isobenzofurandione,4-nitro-
  • 3-Isobenzofurandione,4-nitro-1
  • NSC 4134
  • 3-Nitrophthalic anhydride, synthesis grade
  • 4-Nitrobenzo[c]furan-1,3-dione, 4-Nitro-2-benzofuran-1,3-dione, 4-Nitroisobenzofuran-1,3-dione
  • 3-Nitrophthalic anhydride,97%
  • Phthalic anhydride, 3-nitro- (6CI,7CI,8CI)
  • 3-Nitrophthalic anhydride 98%
  • 3-Nitrophthalic anhydride98%
  • The 3- nitrophthalicanhydridetwo
  • 4-Nitro-2-benzofuran-1,3-dione
  • 4-nitro-3-isobenzofurandione
  • Phthalic anhydride, 3-nitro-
  • 4-NITRO-ISOBENZOFURAN-1,3-DIONE
  • 3-Nitrophthalic Acid Anhydride
  • NSC 27006
  • 3-NITROPHTHALIC ANHYDRIDE
  • 1-Amino-2-Indolinon (CIS)
  • 4-Nitro-1,3-iso benzofurandione
  • 3-NITROPHTHALIC ANHYDRIDE ,99+%
  • 3-NitrophthaL
  • Phthalic anhydride, 3-nitro- (8CI)
  • 3-NitrophthalicAnhydride&gt
  • 3-NITROPHTHALIC ANHYDRIDE FOR SYNTHESIS
  • Pomalidomide INT
  • Pomalidomide Impurity 36
  • RSSYY(Perospirone Hydrochloride Hydrate)-9
  • 3-Nitrophthalic anhydride?New
  • Apremilast Impurity 90
  • Pomadomide impurity 36.
  • 641-70-3
  • C8H3NO5
  • O2NC6H3CO2O
  • Organic Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Building Blocks
  • Anhydride Monomers
  • Monomers
  • Polymer Science
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Organic Building Blocks
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Chemical Synthesis
  • Organic Building Blocks
  • Amines
  • Aromatics
  • Intermediates
  • Phthalic Acids, Esters and Derivatives
  • Dyes intermediates