ChemicalBook > CAS DataBase List > 3-Nitrophthalic anhydride

3-Nitrophthalic anhydride

Product Name
3-Nitrophthalic anhydride
CAS No.
641-70-3
Chemical Name
3-Nitrophthalic anhydride
Synonyms
1,3-Isobenzofurandione, 4-nitro-;3-Nitrophthalic Acid Anhydride;4-NITRO-ISOBENZOFURAN-1,3-DIONE;NSC 4134;NSC 27006;3-NitrophthaL;Pomalidomide INT;Apremilast Impurity 90;Pomadomide impurity 36.;Pomalidomide Impurity 36
CBNumber
CB8116378
Molecular Formula
C8H3NO5
Formula Weight
193.11
MOL File
641-70-3.mol
More
Less

3-Nitrophthalic anhydride Property

Melting point:
163-165 °C (lit.)
Boiling point:
329.3°C (rough estimate)
Density 
1.6392 (rough estimate)
refractive index 
1.4700 (estimate)
storage temp. 
Store below +30°C.
form 
Crystalline Powder
color 
Beige to yellow
Water Solubility 
MAY DECOMPOSE
Sensitive 
Moisture Sensitive
BRN 
179963
CAS DataBase Reference
641-70-3(CAS DataBase Reference)
NIST Chemistry Reference
3-Nitrophthalic anhydride(641-70-3)
EPA Substance Registry System
1,3-Isobenzofurandione, 4-nitro- (641-70-3)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
F 
10-21
TSCA 
Yes
HS Code 
29173980
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.20903
Product name
3-Nitrophthalic anhydride
Purity
for synthesis
Packaging
25g
Price
$87.5
Updated
2024/03/01
Sigma-Aldrich
Product number
8.20903
Product name
3-Nitrophthalic anhydride
Purity
for synthesis
Packaging
100g
Price
$164
Updated
2024/03/01
Sigma-Aldrich
Product number
156884
Product name
3-Nitrophthalic anhydride
Purity
98%
Packaging
5g
Price
$76.2
Updated
2024/03/01
Sigma-Aldrich
Product number
156884
Product name
3-Nitrophthalic anhydride
Purity
98%
Packaging
25g
Price
$148.8
Updated
2024/03/01
TCI Chemical
Product number
N0245
Product name
3-Nitrophthalic Anhydride
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$33
Updated
2024/03/01
More
Less

3-Nitrophthalic anhydride Chemical Properties,Usage,Production

Chemical Properties

Beige to yellow crystalline powder

Uses

An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472). Reactions with aminoquinazolinones yield phthalimidoquinazolinones.

Uses

4-Nitrophthalic Anhydride is an intermediate for the synthesis of the benzimidazole PARP inhibitor I, ABT-472. It reacts with aminoquinazolinones to yield phthalimidoquinazolinones.

Preparation

3-Nitrophthalic anhydride can be prepared by heating 3-nitrophthalic acid under various conditions and by the action of acetic anhydride, essentially as in the procedure described. The direct nitration of phthalic anhydride yields 3-nitrophthalic anhydride together with the isomeric 4-nitro compound.

Purification Methods

Crystallise it from *C6H6, *C6H6/pet ether, Me2CO, AcOH, or Ac2O (m 164-165o). Dry it at 100o. [Beilstein 17 III/IV 6149, 17/11 V 266.]

3-Nitrophthalic anhydride Preparation Products And Raw materials

Raw materials

3-Nitrophthalic acid

Preparation Products

More
Less

3-Nitrophthalic anhydride Suppliers

Americas 1 Belgium 2 Canada 2 CHINA 315 Europe 1 France 1 Germany 7 India 23 Japan 4 Poland 1 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 17 United States 46 Global 424
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
MilliporeSigma (Sigma-Aldrich Corp.)
Tel
--
Fax
--
Email
@sial.com
Country
United States
ProdList
5414
Advantage
58
Sinova Inc.
Tel
--
Fax
--
Email
sales@sinovainc.com
Country
United States
ProdList
4009
Advantage
58
Fluorochem Ltd.
Tel
--
Fax
--
Email
enquiries@fluorochem.co.uk
Country
United States
ProdList
4583
Advantage
58
Parchem Fine & Specialty Chemicals
Tel
--
Fax
--
Email
info@parchem.com
Country
United States
ProdList
1031
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Combi-Blocks, Inc.
Tel
--
Fax
--
Email
les@combi-blocks.com
Country
United States
ProdList
2555
Advantage
58
Wilshire Technologies, Inc.
Tel
--
Fax
--
Email
info@wilshiretechnologies.com
Country
United States
ProdList
893
Advantage
58
Accela ChemBio Inc.
Tel
--
Fax
--
Email
info@accelachem.com
Country
United States
ProdList
1054
Advantage
50
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
TCI America, Inc. (part of Tokyo Chemical Industry)
Tel
--
Fax
--
Email
Angelina.Crew@tcichemicals.com
Country
United States
ProdList
2053
Advantage
58
OX CHEM
Tel
--
Fax
--
Email
sales@ox-chem.com
Country
United States
ProdList
759
Advantage
50
OMKROWN PHARMACHEM PVT LTD
Tel
--
Fax
--
Email
info@omkrown.com
Country
United States
ProdList
37
Advantage
34
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Wilshire Chemical Company Inc.
Tel
--
Fax
--
Email
WilshrChem@AOL.COM
Country
United States
ProdList
3498
Advantage
58
Daniel Lab Canada
Tel
--
Fax
--
Country
United States
ProdList
273
Advantage
50
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Chem-Impex International, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6730
Advantage
64
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Orex Pharwww.orgamol.comma Pvt., Ltd
Tel
--
Fax
--
Country
United States
ProdList
67
Advantage
51
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
CiVentiChem
Tel
--
Fax
--
Email
debra@cvchem.com
Country
United States
ProdList
1340
Advantage
55
City Chemicals Corporation
Tel
--
Fax
--
Country
United States
ProdList
6460
Advantage
72
Eastern Chemical Corp.
Tel
--
Fax
--
Email
eastern@u-g.com
Country
United States
ProdList
2786
Advantage
34
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
MP Biomedicals, Inc.
Tel
--
Fax
--
Country
United States
ProdList
6561
Advantage
81
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
More
Less

View Lastest Price from 3-Nitrophthalic anhydride manufacturers

Asia Chem I and E (Jiangsu) Co Ltd
Product
3-Nitrophthalic anhydride 641-70-3
Price
US $62.79/Kg/Drum
Min. Order
25Kg/Drum
Purity
98.00%HPLC
Supply Ability
8.8tons/month
Release date
2021-09-23
Hebei Chuanghai Biotechnology Co,.LTD
Product
3-Nitrophthalic anhydride 641-70-3
Price
US $10.70/kg
Min. Order
10kg
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23
Hebei Kangcang new material Technology Co., LTD
Product
3-Nitrophthalic anhydride 641-70-3
Price
US $9.00-80.00/g
Min. Order
10g
Purity
min99%
Supply Ability
10 tons
Release date
2024-03-26

641-70-3, 3-Nitrophthalic anhydrideRelated Search:

3-Fluorophthalic anhydride 4-BROMO PHTHALIC ANHYDRUS Dimethyl phthalate cis-1,2,3,6-Tetrahydrophthalic anhydride Isatoic Anhydride 2-Nitrobenzoic acid 2-Nitrobenzaldehyde CIS-BUTENEDIOIC ANHYDRIDE PHTHALAMIDE O-Phthalimide Dibutyl phthalate Phthalonitrile Phthalic anhydride 3-Nitrophthalic acid 3-Nitrophthalhydrazide 3-Nitrophthalimide METHYL 2-NITROBENZOATE 3-(METHOXYMETHYL)ANILINE

  • 1,3-Isobenzofurandione, 4-nitro-
  • 1,3-Isobenzofurandione,4-nitro-
  • 3-Isobenzofurandione,4-nitro-1
  • NSC 4134
  • 3-Nitrophthalic anhydride, synthesis grade
  • 4-Nitrobenzo[c]furan-1,3-dione, 4-Nitro-2-benzofuran-1,3-dione, 4-Nitroisobenzofuran-1,3-dione
  • 3-Nitrophthalic anhydride,97%
  • Phthalic anhydride, 3-nitro- (6CI,7CI,8CI)
  • 3-Nitrophthalic anhydride 98%
  • 3-Nitrophthalic anhydride98%
  • The 3- nitrophthalicanhydridetwo
  • 4-Nitro-2-benzofuran-1,3-dione
  • 4-nitro-3-isobenzofurandione
  • Phthalic anhydride, 3-nitro-
  • 4-NITRO-ISOBENZOFURAN-1,3-DIONE
  • 3-Nitrophthalic Acid Anhydride
  • NSC 27006
  • 3-NITROPHTHALIC ANHYDRIDE
  • 1-Amino-2-Indolinon (CIS)
  • 4-Nitro-1,3-iso benzofurandione
  • 3-NITROPHTHALIC ANHYDRIDE ,99+%
  • 3-NitrophthaL
  • Phthalic anhydride, 3-nitro- (8CI)
  • 3-NitrophthalicAnhydride&gt
  • 3-NITROPHTHALIC ANHYDRIDE FOR SYNTHESIS
  • Pomalidomide INT
  • Pomalidomide Impurity 36
  • RSSYY(Perospirone Hydrochloride Hydrate)-9
  • 3-Nitrophthalic anhydride?New
  • Apremilast Impurity 90
  • Pomadomide impurity 36.
  • 641-70-3
  • C8H3NO5
  • O2NC6H3CO2O
  • Organic Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Building Blocks
  • Anhydride Monomers
  • Monomers
  • Polymer Science
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Organic Building Blocks
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acid Anhydrides
  • Chemical Synthesis
  • Organic Building Blocks
  • Amines
  • Aromatics
  • Intermediates
  • Phthalic Acids, Esters and Derivatives
  • Dyes intermediates