ChemicalBook > CAS DataBase List > Hydrocortisone

Hydrocortisone

Product Name
Hydrocortisone
CAS No.
74050-20-7
Chemical Name
Hydrocortisone
Synonyms
hydrocortisone aceponate;Methylprednisolone Impurity 45;Hydrocortisone 17-Propionate 21-Acetate;Efficort;Suniderma;Hydrocortisonepropylacetate;Hydrocortisone 17-propionate 21-acetate in Acetonitrile;Suniderma|||Efficort|||Hydrocortisone 17-propionate 21-acetate;Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-17-(1-oxopropoxy)-, (11β)-;[(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
CBNumber
CB81178906
Molecular Formula
C26H36O7
Formula Weight
460.56
MOL File
74050-20-7.mol
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Hydrocortisone Property

Melting point:
144-146°C
Density 
1.23±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Pale Beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

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N-Bromosuccinimide Price

TRC
Product number
H714628
Product name
Hydrocortisone17-Propionate21-Acetate
Packaging
25mg
Price
$120
Updated
2021/12/16
TRC
Product number
H714628
Product name
Hydrocortisone17-Propionate21-Acetate
Packaging
100mg
Price
$320
Updated
2021/12/16
TRC
Product number
H714628
Product name
Hydrocortisone17-Propionate21-Acetate
Packaging
50mg
Price
$175
Updated
2021/12/16
Biosynth Carbosynth
Product number
FH23886
Product name
Hydrocortisone 17-propionate 21-acetate
Packaging
50mg
Price
$280
Updated
2021/12/16
Biosynth Carbosynth
Product number
FH23886
Product name
Hydrocortisone 17-propionate 21-acetate
Packaging
250mg
Price
$1040
Updated
2021/12/16
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Hydrocortisone Chemical Properties,Usage,Production

Description

Hydrocortisone aceponate is the 17-a-propionate derivative of hydrocortisone-21-acetate. Its is reportedly significantly superior to the latter in the treatment of dermatoses of varying severity.

Chemical Properties

White to Off-White Solid

Originator

Beiersdorf (W.Germany)

Uses

A new topical hydrocortisone derivative with esterification in positions 17 and 21, inhibit the incorporation of [3H]thymidine in DNA in human skin fibroblasts less strongly than the halogenated glucocorticosteroids betamethasone 17-valerate and clobetasol 17-propionate. Glucocorticosteroid.

Definition

ChEBI: Hydrocortisone aceponate is a corticosteroid hormone.

brand name

Retef

Hydrocortisone Preparation Products And Raw materials

Raw materials

Preparation Products

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74050-20-7, HydrocortisoneRelated Search:


  • hydrocortisone aceponate
  • [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
  • [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyethanoyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate
  • propionic acid [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-3-keto-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] ester
  • Hydrocortisone 17-Propionate 21-Acetate
  • Hydrocortisonepropylacetate
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-17-(1-oxopropoxy)-, (11β)-
  • Efficort
  • Suniderma
  • Methylprednisolone Impurity 45
  • Suniderma|||Efficort|||Hydrocortisone 17-propionate 21-acetate
  • (8S,9S,10R,11S,13S,14S,17R)-17-(2-Acetoxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl propionate
  • Hydrocortisone 17-propionate 21-acetate in Acetonitrile
  • 74050-20-7
  • C26H36O7
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • API