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β-Muricholic Acid

Product Name
β-Muricholic Acid
CAS No.
2393-59-1
Chemical Name
β-Muricholic Acid
Synonyms
6β;β-MCA;7β-triol;β-Muricholic Acid;5β-Cholanic Acid-3α;2H5]-β-Muricholic Acid;Ursodeoxycholic Acid Impurity 30;5β-CHOLANIC ACID-3α, 6β, 7β-TRIOL;βMuricholic Acid,β Muricholic Acid;3a,6b,7b-Trihydroxy-5b-cholanoic acid
CBNumber
CB81235447
Molecular Formula
C24H40O5
Formula Weight
408.58
MOL File
2393-59-1.mol
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β-Muricholic Acid Property

Melting point:
226 °C
Boiling point:
565.7±40.0 °C(Predicted)
Density 
1.184±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO (Slightly), Ethanol (Slightly,Sonicated), Methanol (Slightly), Water (Sligh
form 
powder
pka
4.76±0.10(Predicted)
color 
white to beige
optical activity
[α]/D +59 to +65°, c = 0.1 in methanol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2372
Product name
β-Muricholic Acid
Purity
≥98% (HPLC)
Packaging
5mg
Price
$237
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2372
Product name
β-Muricholic Acid
Purity
≥98% (HPLC)
Packaging
25mg
Price
$334
Updated
2024/03/01
Cayman Chemical
Product number
20287
Product name
β-Muricholic Acid
Purity
≥95%
Packaging
1mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
20287
Product name
β-Muricholic Acid
Purity
≥95%
Packaging
5mg
Price
$404
Updated
2024/03/01
Cayman Chemical
Product number
20287
Product name
β-Muricholic Acid
Purity
≥95%
Packaging
10mg
Price
$750
Updated
2024/03/01
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β-Muricholic Acid Chemical Properties,Usage,Production

Description

β-Muricholic acid (β-MCA) is a murine-specific primary bile acid. Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet. Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.

Uses

β-Muricholic Acid is an bile acid found in urine. β-Muricholic Acid has been used in studies of down regulation of transporter protein through ubiquitin dependent protein degradation.

Definition

ChEBI: Beta-muricholic acid is a member of the class of muricholic acids in which the hydroxy groups at positions 6 and 7 both have beta configuration. It is a member of muricholic acids, a 6beta-hydroxy steroid and a 7beta-hydroxy steroid. It is a conjugate acid of a beta-muricholate.

β-Muricholic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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β-Muricholic Acid Suppliers

ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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J & K SCIENTIFIC LTD.
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