β-Muricholic Acid

Product Name: β-Muricholic Acid
CAS No.: 2393-59-1
Chemical Name: β-Muricholic Acid
Synonyms: 6β;β-MCA;7β-triol;β-Muricholic Acid;5β-Cholanic Acid-3α;2H5]-β-Muricholic Acid;Ursodeoxycholic Acid Impurity 30;5β-CHOLANIC ACID-3α, 6β, 7β-TRIOL;βMuricholic Acid,β Muricholic Acid;3a,6b,7b-Trihydroxy-5b-cholanoic acid
CBNumber: CB81235447
Molecular Formula: C24H40O5
Formula Weight: 408.58
MOL File: 2393-59-1.mol

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β-Muricholic Acid Property

Melting point:: 226 °C
Boiling point:: 565.7±40.0 °C(Predicted)
Density: 1.184±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO (Slightly), Ethanol (Slightly,Sonicated), Methanol (Slightly), Water (Sligh
form: powder
pka: 4.76±0.10(Predicted)
color: white to beige
optical activity: [α]/D +59 to +65°, c = 0.1 in methanol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2372
Product name: β-Muricholic Acid
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $237
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2372
Product name: β-Muricholic Acid
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $334
Updated: 2024/03/01

Cayman Chemical

Product number: 20287
Product name: β-Muricholic Acid
Purity: ≥95%
Packaging: 1mg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 20287
Product name: β-Muricholic Acid
Purity: ≥95%
Packaging: 5mg
Price: $404
Updated: 2024/03/01

Cayman Chemical

Product number: 20287
Product name: β-Muricholic Acid
Purity: ≥95%
Packaging: 10mg
Price: $750
Updated: 2024/03/01

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β-Muricholic Acid Chemical Properties,Usage,Production

Description

β-Muricholic acid (β-MCA) is a murine-specific primary bile acid. Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet. Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.

Uses

β-Muricholic Acid is an bile acid found in urine. β-Muricholic Acid has been used in studies of down regulation of transporter protein through ubiquitin dependent protein degradation.

Definition

ChEBI: Beta-muricholic acid is a member of the class of muricholic acids in which the hydroxy groups at positions 6 and 7 both have beta configuration. It is a member of muricholic acids, a 6beta-hydroxy steroid and a 7beta-hydroxy steroid. It is a conjugate acid of a beta-muricholate.

β-Muricholic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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β-Muricholic Acid Suppliers

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2393-59-1, β-Muricholic AcidRelated Search:

Butyrylcholinesterase Obeticholic Acid Ursodeoxycholic acid Chenodeoxycholic acid 4-[(5S,7S,8S,10S,13R,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid (4R)-4-[(3R,5R,8R,9S,10S,12R,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid URSODEOXYCHOLIC-2,2,4,4-D4 ACID Deoxyursocholic acid methyl ester (5a,7b)-7-hydroxy-3-oxo-Cholan-24-oic acid 7-Oxyisotithocholic Acid 3alpha-Hydroxy-7-oxo-5beta-cholanic Acid LITHOCHOLIC ACID 3,7-DIKETO-5BETA-CHOLAN-24-OIC ACID (3a,5b,7a,12b)-3,7,12-trihydroxy-Cholan-24-oic acid (3α,5β,7β)- 3,7,22-Trihydroxycholan-24-oic Acid α-Muricholic Acid (3b,5b,7a,12a)-3,7,12-trihydroxy-Cholan-24-oic acid (4R)-4-[(3S,5S,7S,8S,9S,10R,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid

(3a,5b,6b,7b)-3,6,7-trihydroxy-Cholan-24-oic acid

3a,6b,7b-Trihydroxy-5b-cholanoic acid

(3α,5β,6β,7β)-3,6,7-Trihydroxycholan-24-oic acid

β-Muricholic Acid

Ursodeoxycholic Acid Impurity 30

5β-Cholanic Acid-3α

6β

7β-triol

β-MCA

2H5]-β-Muricholic Acid

βMuricholic Acid,β Muricholic Acid

Cholan-24-oic acid, 3,6,7-trihydroxy-, (3α,5β,6β,7β)-

5β-CHOLANIC ACID-3α, 6β, 7β-TRIOL

2393-59-1

Pharmaceuticals, Intermediates & Fine Chemicals, Steroids