ChemicalBook > CAS DataBase List > ADRENORPHIN

ADRENORPHIN

Product Name: ADRENORPHIN
CAS No.: 88377-68-8
Chemical Name: ADRENORPHIN
Synonyms: METORPHIN;ADRENORPHIN;METORPHAMIDE;METORPHINAMIDE;Adrenorphin(3TFA);adrenorphin amide;Adrenorphin (human);ADRENORPHIN (BOVINE);Adrenorphin (metorphamide);Tyr-Gly-Gly-Phe-Arg-Arg-Val-NH2
CBNumber: CB8129589
Molecular Formula: C44H69N15O9S
Formula Weight: 984.18
MOL File: 88377-68-8.mol

Less

ADRENORPHIN Property

Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: insoluble in EtOH; ≥48.7 mg/mL in H2O; ≥98.4 mg/mL in DMSO
pka: 9.97±0.15(Predicted)
form: Solid
color: White to off-white
Sequence: H-Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val-NH2

Less

Safety

WGK Germany: 3

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

ApexBio Technology

Product number: A1032
Product name: Adrenorphin
Packaging: 25mg
Price: $175
Updated: 2021/12/16

ChemScene

Product number: CS-0027637
Product name: Adrenorphin
Purity: 95.49%
Packaging: 5mg
Price: $210
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0000414
Product name: ADRENORPHIN
Purity: 95.00%
Packaging: 1MG
Price: $597.89
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0000414
Product name: ADRENORPHIN
Purity: 95.00%
Packaging: 2MG
Price: $604.64
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0000414
Product name: ADRENORPHIN
Purity: 95.00%
Packaging: 5MG
Price: $735.63
Updated: 2021/12/16

Less

ADRENORPHIN Chemical Properties,Usage,Production

Uses

Adrenorphin is a opioid octapeptide, acting as a potent agonist of μ-opioid receptor, with Ki of 12 nM.

Biological Activity

adrenorphin (metorphamide) is a potent inhibitor of nicotine-induced adrenaline and noradrenaline release with ic50 value of 10 μm [1].adrenorphin (metorphamide) is an endogenous, c-terminally amidated, opioid octapeptide (tyr-gly-gly-phe-met-arg-arg-val-nh2) that is produced from proteolytic cleavage of proenkephalin a and is widely distributed throughout the mammalian brain [2].adrenorphin (metorphamide) is selective nicotine-induced adrenaline and noradrenaline release inhibitor and has higher than 100-fold more potent than the reported nicotine-induced adrenaline and noradrenaline release inhibitor met5-enkephalin. when tested with bovine adrenal chromaffin cells, adrenorphin (metorphamide) showed inhibition on 5 μm nicotine-induced atp release by almost 50% at 5μm and the inhibition was not in a dose-dependent manner [1]. in bioassays and binding assays, metorphamide exhibited high μ-binding activity, as well as κ-binding activity with nearly half percent toμ-binding activity, while showed no activity on δ-binding [2].

IC 50

μ Opioid Receptor/MOR

References

[1]. marley, p.d., k.i. mitchelhill, and b.g. livett, metorphamide, a novel endogenous adrenal opioid peptide, inhibits nicotine-induced secretion from bovine adrenal chromaffin cells. brain res, 1986. 363(1): p. 10-7.
[2]. weber, e., et al., metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. proc natl acad sci u s a, 1983. 80(23): p. 7362-6.

ADRENORPHIN Preparation Products And Raw materials

Raw materials

Preparation Products

Less

ADRENORPHIN Suppliers

China 96 Japan 1 Switzerland 1 United States 14 Global 112

Alabiochem Tech.Co., Ltd.

Tel: 512-58900862 400-0707518
Fax: 0086-512-56765862
Email: sales@alabiochem.com
Country: China
ProdList: 970
Advantage: 59

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29759
Advantage: 68

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4802
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 0571-88211921
Email: sales1@gotopbio.com
Country: CHINA
ProdList: 2609
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5167
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Nanjing chengqimei Biotechnology Co., Ltd

Tel: 19850819832
Email: 2173594524@qq.com
Country: China
ProdList: 2638
Advantage: 58

Wuxi Helen Biotechnology Co., Ltd.,

Tel: 0510-85629785 18013409632
Fax: 0510-85625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 14081
Advantage: 58

Nanjing TGpeptide Biotechnology Co.,Ltd.

Tel: 18115476705
Email: sales@tgpeptide.com
Country: China
ProdList: 3058
Advantage: 58

Ontores Biotech

Tel: 0571-88760729 18072970094
Email: supports@ontorespeptide.com
Country: China
ProdList: 2696
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 15397062932
Email: sales1@gotopbio.com
Country: China
ProdList: 2923
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 29668
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 13675144456
Email: alan.chow@synzest.com
Country: China
ProdList: 9470
Advantage: 58

Shaoxing Junyu Biotechnology Co., LTD

Tel: 0571-0571-88211921 19105816207
Email: sales4@gotopbio.com
Country: China
ProdList: 5144
Advantage: 58

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Country: China
ProdList: 6979
Advantage: 58

Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 29784
Advantage: 58

Hangzhou Baige Pharmaceutical Technology Co. , Ltd.

Tel: 0571-85350119 15888826472
Email: 15888826472@163.com
Country: China
ProdList: 2729
Advantage: 58

Shanghai HongTide Biotechnology Co.,Ltd.

Tel: 15318089928
Email: alex@hanhonggroup.com
Country: China
ProdList: 4604
Advantage: 58

Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd

Tel: 13770887460
Email: wenxi@jszkhy.com
Country: China
ProdList: 1354
Advantage: 58

Combio (Suzhou) Ltd.

Tel: 17751201929
Email: office@combiosz.com
Country: China
ProdList: 3000
Advantage: 58

https://hanhongsci.com/

Tel: 021-54306202 18917919676
Email: info@hanhongsci.com
Country: China
ProdList: 29995
Advantage: 58

Shandong Mopai Biotechnology Co., Ltd

Tel: 13053322091
Email: admin@mopaikeji.com
Country: China
ProdList: 5830
Advantage: 58

Nanjing Yushengkang Biotechnology Co., Ltd

Tel: 13327808530
Email: 2670965693@qq.com
Country: China
ProdList: 2179
Advantage: 58

Zhejiang Jiekun Biotechnology Co., Ltd

Tel: 0571-88211951 13735575465
Email: sales1@gotopbio.com
Country: China
ProdList: 4880
Advantage: 58

Taiyuan Bailihengkang Biotechnology Co., Ltd

Tel: 19135651983
Email: 18611134419@163.com
Country: China
ProdList: 4416
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12000
Advantage: 58

Hangzhou Beiputai Biopharmaceutical Co., Ltd

Tel: 0571-85350119 15888826472
Email: bptsales@163.com
Country: China
ProdList: 3834
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29257
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Enzo Biochem Inc

Tel: Enzo Biochem Inc. 13797054060
Email: Enzoname@qq.com
Country: China
ProdList: 6174
Advantage: 58

Hubei Molcoo Biotechnology Co., Ltd

Tel: 17320513646
Email: anna@molcoo.com
Country: China
ProdList: 3268
Advantage: 58

Cohesion Biosciences

Tel: 0512-67583809
Email: sales@cohesionbio.com
Country: China
ProdList: 6282
Advantage: 58

Nanjing Typeptide Biotechnology Co.,Ltd.

Tel: 19941518170
Email: sales@typeptide.com
Country: China
ProdList: 3920
Advantage: 58

LEON (NANJING) BIOTECHNOLOGY CO., LTD.

Tel: +8615051830413
Email: sales.njleonbiotech@gmail.com
Country: China
ProdList: 5482
Advantage: 58

Moxin Chemicals

Tel: +86-17320513646 +8617320513646
Email: anna@molcoo.com
Country: China
ProdList: 10000
Advantage: 58

DAYANG CHEM (HANGZHOU) CO.,LTD

Tel: +86-88938639 +86-17705817739
Email: info@dycnchem.com
Country: China
ProdList: 53899
Advantage: 58

Less

View Lastest Price from ADRENORPHIN manufacturers

Career Henan Chemical Co

Product: ADRENORPHIN 88377-68-8
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-18

88377-68-8, ADRENORPHINRelated Search:

(MET(O)5)-ENKEPHALIN [LEU5]-ENKEPHALIN MET-ENKEPHALIN-ARG-PHE H-TYR-GLY-GLY-PHE-LEU-ARG-ARG-OH MERGL LEU-ENKEPHALIN-ARG MET-ENKEPHALIN-ARG-ARG H-TYR-LYS-GLY-ARG-CYCLO(-GLU-TYR-ILE-LYS)-LEU-ILE-THR-ARG-PRO-ARG-TYR-NH2 ADRENORPHIN (FREE ACID),ADRENORPHIN 1-5-adrenorphin(human ADRENORPHIN BAM 18P PEPTIDE E BAM-12P BAM-22P TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-GLY ([125I]-TYR)-BAM-12P ([125I]-TYR)-BAM-22P

H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2

METORPHIN

METORPHINAMIDE

Adrenorphin(3TFA)

METORPHAMIDE

ADRENORPHIN

ADRENORPHIN (BOVINE)

TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-NH2

PROENKEPHALIN (206-213) (BOVINE)

tyr-gly-gly-phe-met-arg-arg-val amide

TYROSINE-GLYCINE-GLYCINE-PHENYLALANINE-METHIONINE-ARGININE- ARGININE-VALINE AMIDE)

adrenorphin amide

Metorphamide, Tyr-Gly-Gly-Phe-Met-Arg-Arg-Val amide

Tyr-Gly-Gly-Phe-Arg-Arg-Val-NH2

Adrenorphin (metorphamide)

L-Valinamide, L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-

Adrenorphin (human)

Adrenorphin 3TFA(88377-68-8(free base))

Adrenorphin 3TFA(88377688(free base)),Adrenorphin 3TFA(88377 68 8(free base))

88377-68-8

C44H69N15O9S

C44H69N15O9S1

Peptide

CancerBiology