ChemicalBook > CAS DataBase List > LUPULONE

LUPULONE

Product Name
LUPULONE
CAS No.
468-28-0
Chemical Name
LUPULONE
Synonyms
lupulon;b’’-acid;LUPULONE;B-LUPULIC ACID;lohexadien-1-one;BETA-BITTER ACID;BETA-LUPULIC ACID;Lupulone beta-acid;Coclaurine Impurity 3;1-Amino-8-naphthol-3,5-disulfonic acid
CBNumber
CB8136556
Molecular Formula
C26H38O4
Formula Weight
414.58
MOL File
468-28-0.mol
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LUPULONE Property

Melting point:
93℃
Boiling point:
453.43°C (rough estimate)
Density 
1.045±0.06 g/cm3 (20 ºC 760 Torr)
vapor pressure 
0Pa at 20℃
refractive index 
1.4840 (estimate)
storage temp. 
Store at -20°C
solubility 
Methanol: slightly soluble
form 
A solid
pka
4.50±1.00(Predicted)
Water Solubility 
1g/L at 20℃
Stability:
Hygroscopic
LogP
4.5 at 20℃
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
2811
RTECS 
OK5950000
HazardClass 
6.1(b)
PackingGroup 
III
Toxicity
LD50 in mice, rats (mg/kg): 525, 100 orally (Hnsel, Wagener)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28481
Product name
Lupulone
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
28481
Product name
Lupulone
Packaging
10mg
Price
$384
Updated
2024/03/01
Cayman Chemical
Product number
28481
Product name
Lupulone
Packaging
5mg
Price
$202
Updated
2024/03/01
TRC
Product number
L478000
Product name
Lupulone
Packaging
10mg
Price
$185
Updated
2021/12/16
Biosynth Carbosynth
Product number
FL74820
Product name
Lupulone
Packaging
10mg
Price
$300
Updated
2021/12/16
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LUPULONE Chemical Properties,Usage,Production

Uses

Lupulone is a hop plant (Humulus lupulus L.) acid that inhibits tumorigenicity of hepatocellular carcinoma cells.

Definition

ChEBI: Lupulone is a beta-bitter acid in which the acyl group is specified as 3-methylbutanoyl. It has a role as an antimicrobial agent, an apoptosis inducer, an angiogenesis inhibitor and an antineoplastic agent. It is a conjugate acid of a lupulone(1-).

Purification Methods

Crystallise Lupulon from 90% MeOH, hexane or pet ether at low temperature. It has also been purified by chromatography through Kieselgel. [Wieland et al. Chem Ber 102 2012 1925, Riedl Chem Ber 85 692 1952, Beilstein 7 II 856, 7 III 4752, 7 IV 2866.]

LUPULONE Preparation Products And Raw materials

Raw materials

Preparation Products

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LUPULONE Suppliers

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View Lastest Price from LUPULONE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
LUPULONE 468-28-0
Price
US $1.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KG
Release date
2024-07-25
Shaanxi Dideu Medichem Co. Ltd
Product
LUPULONE 468-28-0
Price
US $1.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000KG
Release date
2024-07-25
Career Henan Chemical Co
Product
Lupulone 468-28-0
Price
US $1.00/g
Min. Order
1g
Purity
95-99%
Supply Ability
1ton
Release date
2020-01-10

468-28-0, LUPULONERelated Search:

HUMULONE MOSLOFLAVONE Artemether beta-Sitosterol Cnidii Fructus METHYL CYCLOHEXADIENE 2,7-dimethyl-2,6-octadiene 6-Methyl-5-hepten-2-one 1,3-CYCLOHEXADIENE LUPULONE(P) 1,3,5,5-TETRAMETHYL-1,3-CYCLOHEXADIENE 2,5-DIMETHYL-2-OCTEN-6-ONE LUPULONE 2,7-dimethyloct-5-en-4-one 1-METHYL-1,3-CYCLOHEXADIENE 2-(3-ALLYL)-4-PENTEN-1-OL 2,4-DIMETHYL-2,6-HEPTADIENAL 2,2,4-TRIMETHYL-3-HEXENE

  • 2,4-cyclohexadien-1-one,3,5-dihydroxy-4-isovaleryl-2,6,6-tris(3-methyl-2-but
  • 3,5-dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyc
  • b’’-acid
  • lohexadien-1-one
  • lupulon
  • LUPULONE
  • B-LUPULIC ACID
  • BETA-LUPULIC ACID
  • BETA-BITTER ACID
  • 3,5-DIHYDROXY-2,6,6-TRIS(3-METHYL-2-BUTENYL)-4-(3-METHYLBUTYRYL)-2,4-CYCLOHEXADIENONE
  • Lupulone beta-acid
  • 3,5-dihydroxy-2,6,6-tris(3-methylbut-2-enyl)-4-(3-methyl-1-oxobutyl)cyclohexa-2,4-dien-1-one
  • 3,5-dihydroxy-2,6,6-tris(3-methylbuten-2-yl)-4-(3-methyl-1-oxobutyl)cyclohexa-2,4-dien-1-one
  • 1-Amino-8-naphthol-3,5-disulfonic acid
  • 5-Amino-4-hydroxy-1,7-naphthalenedisulfonic acid
  • β-Bitter acid, β-Lupulic acid, 3,5-Dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methylbutyryl)-2,4-cyclohexadienone
  • 3,5-Dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyclohexadien-1-one
  • 3,5-dihydroxy-2-(3-methylbutanoyl)-4,6,6-tris(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one
  • 3,5-dihydroxy-2-isovaleryl-4,6,6-tris(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one
  • 3,5-DIHYDROXY-2-(3-METHYLBUTANOYL)-4,6,6-TRIS(3-METHYLBUT-2-ENYL)CYCLOHE
  • 2,4-Cyclohexadien-1-one,3,5-dihydroxy-2,6,6-tris(3-methyl-2-buten-1-yl)-4-(3-methyl-1-oxobutyl)-
  • Coclaurine Impurity 3
  • 468-28-0
  • Analytical Chromatography Product Catalog
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  • Analytical Standards
  • Hop Compounds