LUPULONE

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Product Name: LUPULONE
CAS No.: 468-28-0
Chemical Name: LUPULONE
Synonyms: lupulon;b’’-acid;LUPULONE;B-LUPULIC ACID;lohexadien-1-one;BETA-BITTER ACID;BETA-LUPULIC ACID;Lupulone beta-acid;Coclaurine Impurity 3;1-Amino-8-naphthol-3,5-disulfonic acid
CBNumber: CB8136556
Molecular Formula: C26H38O4
Formula Weight: 414.58
MOL File: 468-28-0.mol

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LUPULONE Property

Melting point:: 93℃
Boiling point:: 453.43°C (rough estimate)
Density: 1.045±0.06 g/cm3 (20 ºC 760 Torr)
vapor pressure: 0Pa at 20℃
refractive index: 1.4840 (estimate)
storage temp.: Store at -20°C
solubility: Methanol: slightly soluble
form: A solid
pka: 4.50±1.00(Predicted)
Water Solubility: 1g/L at 20℃
Stability:: Hygroscopic
LogP: 4.5 at 20℃

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: 2811
RTECS: OK5950000
HazardClass: 6.1(b)
PackingGroup: III
Toxicity: LD50 in mice, rats (mg/kg): 525, 100 orally (Hnsel, Wagener)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28481
Product name: Lupulone
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 28481
Product name: Lupulone
Packaging: 10mg
Price: $384
Updated: 2024/03/01

Cayman Chemical

Product number: 28481
Product name: Lupulone
Packaging: 5mg
Price: $202
Updated: 2024/03/01

TRC

Product number: L478000
Product name: Lupulone
Packaging: 10mg
Price: $185
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FL74820
Product name: Lupulone
Packaging: 10mg
Price: $300
Updated: 2021/12/16

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LUPULONE Chemical Properties,Usage,Production

Uses

Lupulone is a hop plant (Humulus lupulus L.) acid that inhibits tumorigenicity of hepatocellular carcinoma cells.

Definition

ChEBI: Lupulone is a beta-bitter acid in which the acyl group is specified as 3-methylbutanoyl. It has a role as an antimicrobial agent, an apoptosis inducer, an angiogenesis inhibitor and an antineoplastic agent. It is a conjugate acid of a lupulone(1-).

Purification Methods

Crystallise Lupulon from 90% MeOH, hexane or pet ether at low temperature. It has also been purified by chromatography through Kieselgel. [Wieland et al. Chem Ber 102 2012 1925, Riedl Chem Ber 85 692 1952, Beilstein 7 II 856, 7 III 4752, 7 IV 2866.]

LUPULONE Preparation Products And Raw materials

Raw materials

Preparation Products

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LUPULONE Suppliers

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View Lastest Price from LUPULONE manufacturers

Career Henan Chemical Co

Product: Lupulone 468-28-0
Price: US $1.00/g
Min. Order: 1g
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-10

Career Henan Chemical Co

Product: LUPULONE 468-28-0
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-10

468-28-0, LUPULONERelated Search:

HUMULONE MOSLOFLAVONE Artemether beta-Sitosterol Cnidii Fructus METHYL CYCLOHEXADIENE 2,7-dimethyl-2,6-octadiene 6-Methyl-5-hepten-2-one 1,3-CYCLOHEXADIENE LUPULONE(P) 1,3,5,5-TETRAMETHYL-1,3-CYCLOHEXADIENE 2,5-DIMETHYL-2-OCTEN-6-ONE LUPULONE 2,7-dimethyloct-5-en-4-one 1-METHYL-1,3-CYCLOHEXADIENE 2-(3-ALLYL)-4-PENTEN-1-OL 2,4-DIMETHYL-2,6-HEPTADIENAL 2,2,4-TRIMETHYL-3-HEXENE

2,4-cyclohexadien-1-one,3,5-dihydroxy-4-isovaleryl-2,6,6-tris(3-methyl-2-but

3,5-dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyc

b’’-acid

lohexadien-1-one

lupulon

LUPULONE

B-LUPULIC ACID

BETA-LUPULIC ACID

BETA-BITTER ACID

3,5-DIHYDROXY-2,6,6-TRIS(3-METHYL-2-BUTENYL)-4-(3-METHYLBUTYRYL)-2,4-CYCLOHEXADIENONE

Lupulone beta-acid

3,5-dihydroxy-2,6,6-tris(3-methylbut-2-enyl)-4-(3-methyl-1-oxobutyl)cyclohexa-2,4-dien-1-one

3,5-dihydroxy-2,6,6-tris(3-methylbuten-2-yl)-4-(3-methyl-1-oxobutyl)cyclohexa-2,4-dien-1-one

1-Amino-8-naphthol-3,5-disulfonic acid

5-Amino-4-hydroxy-1,7-naphthalenedisulfonic acid

β-Bitter acid, β-Lupulic acid, 3,5-Dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methylbutyryl)-2,4-cyclohexadienone

3,5-Dihydroxy-2,6,6-tris(3-methyl-2-butenyl)-4-(3-methyl-1-oxobutyl)-2,4-cyclohexadien-1-one

3,5-dihydroxy-2-(3-methylbutanoyl)-4,6,6-tris(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one

3,5-dihydroxy-2-isovaleryl-4,6,6-tris(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one

3,5-DIHYDROXY-2-(3-METHYLBUTANOYL)-4,6,6-TRIS(3-METHYLBUT-2-ENYL)CYCLOHE

2,4-Cyclohexadien-1-one,3,5-dihydroxy-2,6,6-tris(3-methyl-2-buten-1-yl)-4-(3-methyl-1-oxobutyl)-

Coclaurine Impurity 3

468-28-0

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