ChemicalBook > CAS DataBase List > E 7010

E 7010

Product Name
E 7010
CAS No.
141430-65-1
Chemical Name
E 7010
Synonyms
E 7010;CS-505;CS-1806;ABT-751 (E;E7010(ABT-751);ABT-751 ABT751;ABT-751 (E7010);E 7010 ISO 9001:2015 REACH;ABT-751 (E7010);ABT751; ABT 751;ABT751; ABT 751; E7010; E-7010; E 7010
CBNumber
CB81367030
Molecular Formula
C18H17N3O4S
Formula Weight
371.41
MOL File
141430-65-1.mol
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E 7010 Property

Melting point:
162 °C(dec.)
Boiling point:
551.0±60.0 °C(Predicted)
Density 
1.427
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
insoluble in H2O; ≥18.55 mg/mL in DMSO; ≥25.53 mg/mL in EtOH with ultrasonic
form 
powder to crystal
pka
7.86±0.40(Predicted)
color 
White to Yellow to Orange
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Safety

RTECS 
DB2734000
HS Code 
2935.90.9500
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H361Suspected of damaging fertility or the unborn child

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P314Get medical advice/attention if you feel unwell.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
A3169
Product name
ABT-751
Purity
>98.0%(HPLC)
Packaging
10mg
Price
$133
Updated
2024/03/01
TCI Chemical
Product number
A3169
Product name
ABT-751
Purity
>98.0%(HPLC)
Packaging
50mg
Price
$394
Updated
2024/03/01
Cayman Chemical
Product number
22935
Product name
ABT-751
Purity
≥98%
Packaging
5mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
22935
Product name
ABT-751
Purity
≥98%
Packaging
10mg
Price
$143
Updated
2024/03/01
Cayman Chemical
Product number
22935
Product name
ABT-751
Purity
≥98%
Packaging
50mg
Price
$553
Updated
2024/03/01
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E 7010 Chemical Properties,Usage,Production

Description

ABT-751 is a tubulin polymerization inhibitor that binds to the colchicine binding site on β-tubulin (Ki = 3.3 μM). It inhibits tubulin polymerization in a concentration-dependent manner and inhibits growth of 26 human tumor cell lines (IC50s = 0.06-0.08 μg/ml). ABT-751 (100 mg/kg, p.o.) induces tumor regression in NB-1382 neuroblastoma, IRS56 rhabdomyosarcoma, and KT-6 Wilms mouse xenograft models. It also induces tumor endothelial cell retraction and reduces tumor perfusion, but not muscle perfusion, in a 9L rat glioma subcutaneous tumor model.

Definition

ChEBI: N-[2-(4-hydroxyanilino)-3-pyridinyl]-4-methoxybenzenesulfonamide is a sulfonamide.

E 7010 Preparation Products And Raw materials

Raw materials

Preparation Products

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E 7010 Suppliers

TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from E 7010 manufacturers

Dideu Industries Group Limited
Product
E 7010 141430-65-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-09-27
Career Henan Chemical Co
Product
E 7010 141430-65-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-07-11

141430-65-1, E 7010Related Search:


  • E 7010
  • N-[2-(4-HYDROXYANILINO)PYRIDIN-3-YL]-4-METHOXYBENZENE-1-SULFONAMIDE
  • N-[2-[(4-Hydroxyphenyl)amino]-3-pyridyl]-4-methoxybenzenesulfonamide
  • BenzenesulfonaMide, N-[2-[(4-hydroxyphenyl)aMino]-3-pyridinyl]-4-Methoxy-
  • ABT-751 (E7010)
  • N-(2-(4-hydroxyphenylamino)pyridin-3-yl)-4-methoxybenzenesulfonamide
  • ABT-751 (E
  • E7010(ABT-751)
  • ABT-751 (E7010);ABT751; ABT 751
  • CS-1806
  • ABT751; ABT 751; E7010; E-7010; E 7010
  • N-[2-[(4-Hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide
  • CS-505
  • E 7010 ISO 9001:2015 REACH
  • ABT-751 ABT751
  • Microtubule/Tubulin,E 7010,Autophagy,E-7010,Inhibitor,inhibit,ABT 751,ABT751,ABT-751
  • 141430-65-1
  • Inhibitors