E 7010
- Product Name
- E 7010
- CAS No.
- 141430-65-1
- Chemical Name
- E 7010
- Synonyms
- E 7010;CS-505;CS-1806;ABT-751 (E;E7010(ABT-751);ABT-751 ABT751;ABT-751 (E7010);E 7010 ISO 9001：2015 REACH;ABT-751 (E7010);ABT751; ABT 751;ABT751; ABT 751; E7010; E-7010; E 7010
- CBNumber
- CB81367030
- Molecular Formula
- C18H17N3O4S
- Formula Weight
- 371.41
- MOL File
- 141430-65-1.mol
E 7010 Property
- Melting point:
- 162 °C(dec.)
- Boiling point:
- 551.0±60.0 °C(Predicted)
- Density
- 1.427
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- insoluble in H2O; ≥18.55 mg/mL in DMSO; ≥25.53 mg/mL in EtOH with ultrasonic
- form
- powder to crystal
- pka
- 7.86±0.40(Predicted)
- color
- White to Yellow to Orange
Safety
- RTECS
- DB2734000
- HS Code
- 2935.90.9500
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H361Suspected of damaging fertility or the unborn child
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P281Use personal protective equipment as required.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313IF exposed or concerned: Get medical advice/attention.
P314Get medical advice/attention if you feel unwell.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A3169
- Product name
- ABT-751
- Purity
- >98.0%(HPLC)
- Packaging
- 10mg
- Price
- $133
- Updated
- 2024/03/01
- Product number
- A3169
- Product name
- ABT-751
- Purity
- >98.0%(HPLC)
- Packaging
- 50mg
- Price
- $394
- Updated
- 2024/03/01
- Product number
- 22935
- Product name
- ABT-751
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $81
- Updated
- 2024/03/01
- Product number
- 22935
- Product name
- ABT-751
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $143
- Updated
- 2024/03/01
- Product number
- 22935
- Product name
- ABT-751
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $553
- Updated
- 2024/03/01
E 7010 Chemical Properties,Usage,Production
Description
ABT-751 is a tubulin polymerization inhibitor that binds to the colchicine binding site on β-tubulin (Ki = 3.3 μM). It inhibits tubulin polymerization in a concentration-dependent manner and inhibits growth of 26 human tumor cell lines (IC50s = 0.06-0.08 μg/ml). ABT-751 (100 mg/kg, p.o.) induces tumor regression in NB-1382 neuroblastoma, IRS56 rhabdomyosarcoma, and KT-6 Wilms mouse xenograft models. It also induces tumor endothelial cell retraction and reduces tumor perfusion, but not muscle perfusion, in a 9L rat glioma subcutaneous tumor model.
Definition
ChEBI: N-[2-(4-hydroxyanilino)-3-pyridinyl]-4-methoxybenzenesulfonamide is a sulfonamide.
E 7010 Preparation Products And Raw materials
Raw materials
Preparation Products
E 7010 Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
View Lastest Price from E 7010 manufacturers
- Product
- E 7010 141430-65-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-27
- Product
- E 7010 141430-65-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-07-11