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4-Deoxypyridoxine hydrochloride

Product Name
4-Deoxypyridoxine hydrochloride
CAS No.
148-51-6
Chemical Name
4-Deoxypyridoxine hydrochloride
Synonyms
nsc3063;4-DEOXYPYRIDOXINE HCL;Vitamin B6 Impurity B;Pyridoxine Impurity B;Vitamin B6 Impurity 2;DEOXYPYRIDOXINE, 4- HCL;Pyridoxine EP Impurity B;Pyridoxine Impurity B HCl;Pyridoxine HCl IMpurity B;Vitamin B6 Impurity 2 HCl
CBNumber
CB8136859
Molecular Formula
C8H12ClNO2
Formula Weight
189.64
MOL File
148-51-6.mol
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4-Deoxypyridoxine hydrochloride Property

Melting point:
274°C(dec.)(lit.)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form 
Solid
color 
White to Pale Red
biological source
synthetic (organic)
Stability:
Hygroscopic
CAS DataBase Reference
148-51-6(CAS DataBase Reference)
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Safety

WGK Germany 
3
RTECS 
UT4800000
HS Code 
29333990
Toxicity
LD50 oral in chicken: 1570mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D0501
Product name
4-Deoxypyridoxine hydrochloride
Purity
analytical standard
Packaging
500mg
Price
$146
Updated
2025/07/31
Sigma-Aldrich
Product number
PHR1694
Product name
Pyridoxine Impurity B
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
50 mg
Price
$658
Updated
2025/07/31
Sigma-Aldrich
Product number
D0501
Product name
4-Deoxypyridoxine hydrochloride
Purity
analytical standard
Packaging
1g
Price
$255
Updated
2025/07/31
TCI Chemical
Product number
D0053
Product name
4-Deoxypyridoxine Hydrochloride
Purity
>98.0%(HPLC)(T)
Packaging
100mg
Price
$40
Updated
2025/07/31
Cayman Chemical
Product number
21863
Product name
4-Deoxypyridoxine (hydrochloride)
Purity
≥98%
Packaging
100mg
Price
$32
Updated
2024/03/01
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4-Deoxypyridoxine hydrochloride Chemical Properties,Usage,Production

Description

4-deoxy Pyridoxine (DOP) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. DOP inhibits sphingosine-1-phosphate (S1P) lyase and reduces cyclic stretch-induced apoptosis in alveolar epithelial MLE-12 cells. DOP (5 mg, i.p.) reduces lysyl oxidase activity by 26% and reduces collagen and elastin crosslinking, resulting in limb abnormalities in chick embryos. It decreases latency to first seizure in mice (ED50 = 1 mmol/kg) and increases the occurrence and duration of myoclonic responses in baboons with photosensitive epilepsy. DOP reduces TNF-α and IL-6 production in mice infected with T. spiralis.

Chemical Properties

Solid

Uses

4-Deoxypyridoxine is the deoxy analogue of Pyridoxine (P991735). 4-Deoxypyridoxine is a vitamin B6 antimetabolite; 4-Deoxypyridoxine can induce a deficient status that alters the function and ultrastructure of EC similar to vascular disease.

References

[1] B SHANE  E E S. Transport and metabolism of vitamin B6 in the yeast Saccharomyces carlsbergensis 4228.[J]. The Journal of Biological Chemistry, 1976, 251 4: 1042-1051.
[2] VIDYANI SURYADEVARA. Sphingolipids in Ventilator Induced Lung Injury: Role of Sphingosine-1-Phosphate Lyase.[J]. ACS Applied Materials & Interfaces, 2018. DOI: 10.3390/ijms19010114
[3] T A BIRD  C I L. The effect of a vitamin B-6 antagonist, 4-deoxypyridoxine, on the cross-linking of collagen in the developing chick embryo.[J]. Biochemical Journal, 1983, 210 3: 633-638. DOI: 10.1042/bj2100633
[4] R. W. HORTON  B. S M. Seizures induced by allylglycine, 3-mercaptopropionic acid and 4-deoxypyridoxine in mice and photosensitive baboons, and different modes of inhibition of cerebral glutamic acid decarboxylase[J]. British Journal of Pharmacology, 1973, 49 1: 52-63. DOI: 10.1111/j.1476-5381.1973.tb08267.x
[5] STAVROS FRYDAS . Generation of TNFα, IFNγ, IL-6, IL-4 and IL-10 in mouse serum from trichinellosis: effect of the anti-inflammatory compound 4-deoxypyridoxine (4-DPD)[J]. Immunology letters, 1996, 49 3: Pages 179-184. DOI: 10.1016/0165-2478(96)02501-1

4-Deoxypyridoxine hydrochloride Preparation Products And Raw materials

Raw materials

Pyridoxal phosphate Palladium Hydrochloric acid

Preparation Products

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4-Deoxypyridoxine hydrochloride Suppliers

Americas 1 Canada 1 China 135 Europe 1 Germany 3 India 8 Japan 1 South Korea 1 Switzerland 1 United Kingdom 6 United States 24 Global 182
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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86-21-61259102
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China
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3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
Fax
86-21-50328109
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3bsc@sina.com
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China
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Chembest Research Laboratories Limited
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+86-21-20908456
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021-58180499
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sales@BioChemBest.com
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China
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
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China
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Energy Chemical
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Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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chenyj@titansci.com
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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info@chemlin.com.cn
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China
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Chemsky（shanghai）International Co.,Ltd.
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021-50135380
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shchemsky@sina.com
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China
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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0539-6365991
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3007715519@qq.com
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China
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View Lastest Price from 4-Deoxypyridoxine hydrochloride manufacturers

Career Henan Chemical Co
Product
4-Deoxypyridoxine hydrochloride 148-51-6
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-26

148-51-6, 4-Deoxypyridoxine hydrochlorideRelated Search:

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