5-BROMO-6-HYDROXYNICOTINIC ACID
- Product Name
- 5-BROMO-6-HYDROXYNICOTINIC ACID
- CAS No.
- 41668-13-7
- Chemical Name
- 5-BROMO-6-HYDROXYNICOTINIC ACID
- Synonyms
- 5-Bromo-6-Hydroxy Niacin;5-BROMO-6-HYDROXYNICOTINIC ACID;6-Hydroxy-5-bromonicotinic acid;3-BROMO-5-CARBOXY-2(1H)-PYRIDINONE;5-Bromo-6-hydroxynicotinic acid 97%;5-Bromo-6-hydroxynicotinic acid ,97%;5-BROMO-6-HYDROXYPYRIDINE-3-CARBOXYLIC ACID;5-BROMO-6-HYDROXY-3-PYRIDINECARBOXYLIC ACID;5-bromo-6-oxo-1H-pyridine-3-carboxylic acid;5-Bromo-6-hydroxy-pyridin-3-carboxylic acid
- CBNumber
- CB8137629
- Molecular Formula
- C6H4BrNO3
- Formula Weight
- 218
- MOL File
- 41668-13-7.mol
5-BROMO-6-HYDROXYNICOTINIC ACID Property
- Melting point:
- >300
- Boiling point:
- 348.1±42.0 °C(Predicted)
- Density
- 2.015±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.38±0.50(Predicted)
- form
- powder to crystal
- color
- White to Almost white
- InChI
- InChI=1S/C6H4BrNO3/c7-4-1-3(6(10)11)2-8-5(4)9/h1-2H,(H,8,9)(H,10,11)
- InChIKey
- PQDLYKZCJBGXPQ-UHFFFAOYSA-N
- SMILES
- C1NC(=O)C(Br)=CC=1C(O)=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B5193
- Product name
- 5-Bromo-6-hydroxynicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $57
- Updated
- 2025/07/31
- Product number
- B5193
- Product name
- 5-Bromo-6-hydroxynicotinic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $172
- Updated
- 2025/07/31
- Product number
- B696223
- Product name
- 5-Bromo-6-hydroxynicotinic Acid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- HCH0024564
- Product name
- 5-BROMO-6-HYDROXYNICOTINIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $642.99
- Updated
- 2021/12/16
- Product number
- FB147581
- Product name
- 5-Bromo-6-oxo-1,6-dihydro-3-pyridinecarboxylicacid
- Packaging
- 1g
- Price
- $283
- Updated
- 2021/12/16
5-BROMO-6-HYDROXYNICOTINIC ACID Chemical Properties,Usage,Production
Chemical Properties
Light green solid
Synthesis
5006-66-6
41668-13-7
Synthesis of 5-bromo-6-hydroxynicotinic acid: 6-hydroxynicotinic acid (8 g, 57.6 mmol) was suspended in water (30 mL) and bromine (4.2 mL, 81.4 mmol) was slowly added under ice bath cooling conditions. After addition, the reaction mixture was stirred at room temperature for 24 hours. Upon completion of the reaction, the solid product was collected by filtration, washed with water and dried in a vacuum oven at 40 °C for 24 h to afford 5-bromo-6-hydroxynicotinic acid (12.1 g, 97% yield) as a tan solid. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 8.04 (d, J = 2.53 Hz, 1H), 8.16 (d, J = 2.27 Hz, 1H), 12.59 (br s, 1H), 12.90 (br s, 1H).
References
[1] Journal of Medicinal Chemistry, 2013, vol. 56, # 24, p. 9874 - 9896
[2] Journal of Medicinal Chemistry, 2005, vol. 48, # 15, p. 4892 - 4909
[3] Patent: WO2007/70818, 2007, A1. Location in patent: Page/Page column 103
[4] Patent: WO2006/88919, 2006, A2. Location in patent: Page/Page column 134-135
[5] Patent: US2008/85906, 2008, A1. Location in patent: Page/Page column 15
5-BROMO-6-HYDROXYNICOTINIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BROMO-6-HYDROXYNICOTINIC ACID manufacturers
- Product
- 5-BROMO-6-HYDROXYNICOTINIC ACID 41668-13-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-24
- Product
- 5-BROMO-6-HYDROXYNICOTINIC ACID 41668-13-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-30
- Product
- 5-BROMO-6-HYDROXYNICOTINIC ACID 41668-13-7
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-09