deltonin

Product Name: deltonin
CAS No.: 55659-75-1
Chemical Name: deltonin
Synonyms: deltonin;Deltonin, 10 mM in DMSO;3-O-beta-D-Glucopyranosyl(1-4)-[alpha-L-rhamnopyranosyl(1-2)]-beta-D-glucopyranoside-diosgenin;Deltonin,3-O-β-D-Glucopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside-diosgenin;β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-;Deltonin,Akt,Protein kinase B,PKB,Inhibitor,Extracellular signal regulated kinases,inhibit,ERK,Endogenous Metabolite
CBNumber: CB81377295
Molecular Formula: C45H72O17
Formula Weight: 885.04
MOL File: 55659-75-1.mol

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deltonin Property

Melting point:: 298-300 °C (decomp)
Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: 4°C, protect from light
pka: 12?+-.0.70(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: 300168
Product name: Deltonin
Packaging: 10mg
Price: $546
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD74415
Product name: Deltonin
Packaging: 1mg
Price: $110
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD74415
Product name: Deltonin
Packaging: 2mg
Price: $160
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD74415
Product name: Deltonin
Packaging: 5mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-0019612
Product name: Deltonin
Purity: 99.93%
Packaging: 5mg
Price: $380
Updated: 2021/12/16

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deltonin Chemical Properties,Usage,Production

Uses

Deltonin, a steroidal saponin, isolated from Dioscorea zingiberensis, has antitumor activity; Deltonin inhibits ERK1/2 and AKT activation.

Definition

ChEBI: Deltonin is a triterpenoid.

in vivo

Deltonin (20 and 40 mg/kg, p.o.) reduces the tumor growth of 37.7% and 56.7%, and causes a 50-day survival rate of 60% and 50%, respectively, in mice. Deltonin also inhibits tumor angiogenesis in mice^[1].

IC 50

ERK1; ERK2; Akt

References

[1] Tong QY, et al. Deltonin, a steroidal saponin, inhibits colon cancer cell growth in vitro and tumor growth in vivo via induction of apoptosis and antiangiogenesis. Cell Physiol Biochem. 2011;27(3-4):233-42. DOI:10.1159/000327949
[2] Zhang S, et al. Deltonin induces apoptosis in MDA?MB?231 human breast cancer cells via reactive oxygen species?mediated mitochondrial dysfunction and ERK/AKT signaling pathways. Mol Med Rep. 2013 Mar;7(3):1038-44. DOI:10.3892/mmr.2013.1273

deltonin Preparation Products And Raw materials

Raw materials

Preparation Products

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deltonin Suppliers

China 80 United Kingdom 1 United States 8 Global 89

Dalian Meilun Biotech Co., Ltd.

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Chengdu Biopurify Phytochemicals Ltd.

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Country: China
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Shanghai Tauto Biotech Co., Ltd.

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Country: China
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Shanghai Aspire Biological Technology Co., Ltd.

Tel: 021-61317773
Fax: 021-61486878
Email: sales@aspirebio.com
Country: China
ProdList: 2880
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ALB Technology Limited

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Email: sales@albtechnology.com
Country: United States
ProdList: 2993
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Wuhan ChemFaces Biochemical Co., Ltd.

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Shanghai EFE Biological Technology Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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Grice Rand (Tianjin) Pharmaceutical Co., Ltd.

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View Lastest Price from deltonin manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Deltonin 55659-75-1
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-03-30

Career Henan Chemical Co

Product: deltonin 55659-75-1
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,50kg
Release date: 2020-01-18

55659-75-1, deltoninRelated Search:

Bufalin Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)- beta-Sitosterol 22,25-Epoxy-2,3,14,20-tetrahydroxycholest-7-en-6-one ALLEOSIDE A Resibufogenin Bufotaline Hydroxyecdysone (3beta,25R)-14-Hydroxyspirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-4)]-beta-D-glucopyranoside poricoic acid A 3-methyl ester Notoginsenoside R2 ginsenoside F4 dehydrotumulosic acid panaxydol Dipsanoside A Dipsanoside B

deltonin

3-O-beta-D-Glucopyranosyl(1-4)-[alpha-L-rhamnopyranosyl(1-2)]-beta-D-glucopyranoside-diosgenin

Deltonin,3-O-β-D-Glucopyranosyl-(1→4)-[α-L-rhamnopyranosyl-(1→2)]-β-D-glucopyranoside-diosgenin

β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[β-D-glucopyranosyl-(1→4)]-

Deltonin,Akt,Protein kinase B,PKB,Inhibitor,Extracellular signal regulated kinases,inhibit,ERK,Endogenous Metabolite

Deltonin, 10 mM in DMSO

55659-75-1