ChemicalBook > CAS DataBase List > 2-Hydroxypyridine

2-Hydroxypyridine

Product Name
2-Hydroxypyridine
CAS No.
142-08-5
Chemical Name
2-Hydroxypyridine
Synonyms
Pyridin-2(1H)-one;2-PYRIDONE;2(1h)-pyridinone;2-Pyridinol;Pyridin-2-one;2(1H)-PYRIDONE;2-PYRIDON;2-PYRIDOL;A-PYRIDONE;Pyridone-2
CBNumber
CB8137755
Molecular Formula
C5H5NO
Formula Weight
95.1
MOL File
142-08-5.mol
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2-Hydroxypyridine Property

Melting point:
105-107 °C (lit.)
Boiling point:
280-281 °C (lit.)
Density 
1.39
refractive index 
1.5939 (estimate)
Flash point:
210 °C
storage temp. 
Sealed in dry,Room Temperature
solubility 
450g/l
pka
0.75(at 20℃)
form 
Liquid
color 
Colorless to yellow to brown, darken on storage with no loss of purity
Water Solubility 
Soluble in water 450 g/L @ 20°C and ethanol, slightly soluble in benzene and ether.
BRN 
105786
LogP
-0.593 (est)
CAS DataBase Reference
142-08-5(CAS DataBase Reference)
NIST Chemistry Reference
2(1H)-Pyridinone(142-08-5)
EPA Substance Registry System
2(1H)-Pyridinone (142-08-5)
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Safety

Hazard Codes 
Xi,Xn,T
Risk Statements 
36/37/38-40-25
Safety Statements 
26-36-37/39-22-45-36/37/39
RIDADR 
UN2811
WGK Germany 
3
RTECS 
UV1144050
F 
8
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
HS Code 
29333990
Toxicity
LD50 ipr-mus: 410 mg/kg TOXIA6 23,815,85
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
H56800
Product name
2-Hydroxypyridine
Purity
97%
Packaging
25g
Price
$53.9
Updated
2024/03/01
Sigma-Aldrich
Product number
41152
Product name
2-Hydroxypyridine
Purity
analytical standard
Packaging
100mg
Price
$67.2
Updated
2022/05/15
TCI Chemical
Product number
H0330
Product name
2-Hydroxypyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$37
Updated
2024/03/01
TCI Chemical
Product number
H0330
Product name
2-Hydroxypyridine
Purity
>98.0%(GC)(T)
Packaging
250g
Price
$267
Updated
2024/03/01
Alfa Aesar
Product number
A14522
Product name
2-Hydroxypyridine, 98%
Packaging
25g
Price
$42.65
Updated
2024/03/01
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2-Hydroxypyridine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal

Uses

2-Hydroxypyridine is a bifunctional catalyst for a wide variety of acylation reactions, catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate. It is used in peptide synthesis.

Uses

Catalyst for generating β-oxopropyl carbonates from cyclic carbonates and alcohols and in the aminolysis of a polyglutamate.

Definition

ChEBI: 2-Hydroxypyridine is a monohydroxypyridine that is pyridine substituted by a hydroxy group at position 2. It has a role as a plant metabolite.

General Description

2-Hydroxypyridine, an enolic tautomer of 2-pyridone, belongs to the class of volatile organic compounds (VOCs).

Safety Profile

Moderately toxic by intraperitoneal and intravenous routes. A combustible liquid. When heated to decomposition it emits toxic vapors of NOx.

Purification Methods

Distil the pyridone under vacuum to remove coloured impurity, then recrystallise from *benzene, CCl4, EtOH or CHCl3/diethyl ether. It can be sublimed under high vacuum. [DePue et al. J Am Chem Soc 107 2131 1985, Beilstein 21/7 V 106.]

2-Hydroxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

DI-2-PYRIDYL THIONOCARBONATE Reactive Brilliant Yellow M-7G 2-Hydroxy-5-bromopyridine 5-CHLOROPYRIDIN-2(1H)-ONE disodium 4-[[5-(aminocarbonyl)-1-ethyl-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-3-pyridyl]azo]-6-[(4,6-dichloro-1,3,5-triazin-2-yl)amino]benzene-1,3-disulphonate 3,5-DICHLORO-2-PYRIDONE
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2-Hydroxypyridine Suppliers

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View Lastest Price from 2-Hydroxypyridine manufacturers

JINING XINHE CHEMICAL CO., LTD
Product
2-Hydroxypyridine 142-08-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10ton
Release date
2024-07-20
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
2-Hydroxypyridine 142-08-5
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2021-03-01
Hebei Mojin Biotechnology Co., Ltd
Product
2-Hydroxypyridine 142-08-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-07-28

142-08-5, 2-HydroxypyridineRelated Search:

Hydroxy silicone oil 4-Methylpyridine (+/-)-NICOTINE 2,3,4-Trihydroxybenzoic acid 2-(Hydroxymethyl)pyridine 2-Chloro-5-chloromethylpyridine Sulfasalazine 2,5-Dimethylpyridine Chromium picolinate 4-Hydroxypyridine Pyridin-2-ol Levetiracetam impurity 8 Levetiracetam acid LevetiracetaM IMpurity B (S)-N-(1-aMino-1-oxobutan-2-yl)-4-chlorobutanaMide alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid Levetiracetam impurity 6 Levetiracetam

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  • 3-Fluoro-4-Methylbenzenethiol, >95%
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  • Levetiracetam EP Impurity C
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  • 2-HYDROXYPYRIDINE (2(1H)-Pyridinol) >98%
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