Fukinolide

Product Name: Fukinolide
CAS No.: 18455-98-6
Chemical Name: Fukinolide
Synonyms: Fukinolide;Bakkenolide B;(-)-Bakkenolide B;Spironolactone EP Impurity 16;(1'R,3R,7'aβ)-1'β-Acetoxy-3'aβ,4'β-dimethyl-4-methylene-7'α-[[(2Z)-2-methyl-2-butenoyl]oxy]spiro[oxolane-3,2'-hydrindane]-2-one;2-Butenoic acid, 2-methyl-, (2'R,3'R,3'aR,4'S,7'S,7'aR)-3'-(acetyloxy)decahydro-7',7'a-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'-yl ester, (2Z)-;(Z)-2-Methyl-2-butenoic acid [(3R,3'aα)-3'α-acetoxy-4,5,1',3',3'a,4',5',6',7',7'a-decahydro-7'α,7'aα-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'β-yl] ester
CBNumber: CB81470538
Molecular Formula: C22H30O6
Formula Weight: 390.47
MOL File: 18455-98-6.mol

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Fukinolide Property

Melting point:: 101-102 °C
Boiling point:: 503.0±50.0 °C(Predicted)
Density: 1.16±0.1 g/cm3(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot

Product number: CD32002169
Product name: BakkenolideB
Purity: 95+%
Packaging: 5mg
Price: $802
Updated: 2021/12/16

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Fukinolide Chemical Properties,Usage,Production

Uses

Bakkenolide B is isolated from petasites japonicas leaves and has?anti-allergic and anti-inflammatory effects. Bakkenolide B can be used for the study of asthma[1].

Definition

ChEBI: Bakkenolide B is a terpene lactone.

in vivo

Bakkenolide B (intraperitoneal injection; 1 mg/ml; 1 h before ovalbumin nebulization on days 28, 29, and 30) strongly inhibits the accumulation of eosinophils, macrophages, and lymphocytes to bronchoalveolar lavage fluid (BALF) in ovalbumin-induced asthma mice^[1].

Animal Model:	Ovalbumin-induced asthma mice^[1]
Dosage:	1 mg/ml
Administration:	Intraperitoneal injection; 1 h before ovalbumin nebulization on days 28, 29, and 30
Result:	Exhibited anti-allergic effects in mice.

References

[1] Lee KP, et al. Anti-allergic and anti-inflammatory effects of bakkenolide B isolated from Petasites japonicus leaves.J Ethnopharmacol.?2013 Jul 30;148(3):890-4. DOI:10.1016/j.jep.2013.05.037

Fukinolide Preparation Products And Raw materials

Raw materials

Preparation Products

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Fukinolide Suppliers

China 19 United States 5 Global 24

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3988
Advantage: 66

ALB Technology Limited

Tel: 702-983-3769
Fax: 702-983-3769
Email: sales@albtechnology.com
Country: United States
ProdList: 2993
Advantage: 55

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8447
Advantage: 60

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
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Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
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Absin Bioscience Inc.

Tel: 021-38015121 18438616290
Email: lanwu@univ-bio.com
Country: China
ProdList: 24731
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Shanghai Binsui Biotechnology Co., Ltd.

Tel: 18301908279
Fax: 021-54387656
Email: 1292752157@qq.com
Country: China
ProdList: 7683
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18455-98-6, FukinolideRelated Search:

alpha-Terpineol MOSLOFLAVONE hydroxygenkwanin beta-Sitosterol beta-Eudesmol Hydroxyecdysone Artemether alpha-Cyperone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one Spironolactone

Fukinolide

(-)-Bakkenolide B

(1'R,3R,7'aβ)-1'β-Acetoxy-3'aβ,4'β-dimethyl-4-methylene-7'α-[[(2Z)-2-methyl-2-butenoyl]oxy]spiro[oxolane-3,2'-hydrindane]-2-one

(Z)-2-Methyl-2-butenoic acid [(3R,3'aα)-3'α-acetoxy-4,5,1',3',3'a,4',5',6',7',7'a-decahydro-7'α,7'aα-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'β-yl] ester

Bakkenolide B

2-Butenoic acid, 2-methyl-, (2'R,3'R,3'aR,4'S,7'S,7'aR)-3'-(acetyloxy)decahydro-7',7'a-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'-yl ester, (2Z)-

Spironolactone EP Impurity 16

18455-98-6