ChemicalBook > CAS DataBase List > (-)-TEPHROSIN

(-)-TEPHROSIN

Product Name
(-)-TEPHROSIN
CAS No.
76-80-2
Chemical Name
(-)-TEPHROSIN
Synonyms
Deguelinol I;Isotephrosin;(-)-TEPHROSIN;Hydroxydeguelin;Tephrosin (synthetic);(-)-TEPHROSIN USP/EP/BP;Tephrosin >=95% (LC/MS-ELSD);13,13a-Dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one;3H-Bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7- (7aH)-one,13,13a-dihydro-7a-hydroxy-9,10- dimethoxy-3,3-dimethyl-,(7aR,13aR)-
CBNumber
CB81484766
Molecular Formula
C23H22O7
Formula Weight
410.42
MOL File
76-80-2.mol
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(-)-TEPHROSIN Property

Melting point:
198° (218-220°)
Boiling point:
450.42°C (rough estimate)
Density 
1.2284 (rough estimate)
refractive index 
1.5300 (estimate)
storage temp. 
-20°C
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Cryst.
pka
10.47±0.40(Predicted)
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Safety

Hazard Codes 
N
Risk Statements 
50
Safety Statements 
61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SMB00172
Product name
Tephrosin
Purity
≥95% (LC/MS-ELSD)
Packaging
1mg
Price
$459
Updated
2024/03/01
Cayman Chemical
Product number
19840
Product name
Tephrosin (synthetic)
Packaging
500μg
Price
$183
Updated
2024/03/01
Cayman Chemical
Product number
19840
Product name
Tephrosin (synthetic)
Packaging
1mg
Price
$328
Updated
2024/03/01
TRC
Product number
T102900
Product name
Tephrosin
Packaging
10mg
Price
$1200
Updated
2021/12/16
AK Scientific
Product number
4156BA
Product name
Tephrosin
Packaging
1mg
Price
$461
Updated
2021/12/16
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(-)-TEPHROSIN Chemical Properties,Usage,Production

Uses

Tephrosin as a natural rotenoid obtained from Tephrosia vogelii and displays anticancer activity.

Definition

ChEBI: A member of the class of rotenones that is 13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one substituted with geminal methyl groups at position 3, hydroxy group at position 7a a d methoxy groups at positions 9 and 10 (the 7aR,13aR stereoisomer). It is isolated from the leaves and twigs of Antheroporum pierrei and exhibits antineoplastic and pesticidal activities.

target

ROS | PARP | Autophagy | HSP (e.g. HSP90) | EGFR | Akt | ERK | Caspase | AMPK | mTOR

(-)-TEPHROSIN Preparation Products And Raw materials

Raw materials

Preparation Products

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76-80-2, (-)-TEPHROSINRelated Search:


  • 13,13a-Dihydro-7a-hydroxy-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7(7aH)-one
  • Hydroxydeguelin
  • Isotephrosin
  • Deguelinol I
  • Tephrosin (synthetic)
  • 3H-Bis[1]benzopyrano[3,4-b:6',5'-e]pyran-7- (7aH)-one,13,13a-dihydro-7a-hydroxy-9,10- dimethoxy-3,3-dimethyl-,(7aR,13aR)-
  • Tephrosin >=95% (LC/MS-ELSD)
  • (-)-TEPHROSIN USP/EP/BP
  • (-)-TEPHROSIN
  • 76-80-2
  • Miscellaneous Natural Products