6-HYDROXY-3-PYRIDINEBORONIC ACID
- Product Name
- 6-HYDROXY-3-PYRIDINEBORONIC ACID
- CAS No.
- 903899-13-8
- Chemical Name
- 6-HYDROXY-3-PYRIDINEBORONIC ACID
- Synonyms
- 5-BORONO-2-PYRIDONE;6-HYDROXY-3-PYRIDINEBORONIC ACID;2-Hydroxypyridine-5-boronic acid;(6-Hydroxy-3-pyridyl)boronic acid;(6-oxo-1H-pyridin-3-yl)boronic acid;1,6-Dihydro-6-oxopyridine-3-boronic acid;(6-oxo-5,6-dihydropyridin-3-yl)boronic acid;(6-oxo-1,6-dihydropyridin-3-yl)boronic acid;B-(1,6-dihydro-6-oxo-3-pyridinyl)-Boronic acid;(6-Hydroxypyridin-3-yl)boronic acid - [H26341]
- CBNumber
- CB81486760
- Molecular Formula
- C5H6BNO3
- Formula Weight
- 138.92
- MOL File
- 903899-13-8.mol
6-HYDROXY-3-PYRIDINEBORONIC ACID Property
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml,Ethanol: 1 mg/ml
- form
- A crystalline solid
- pka
- 8.02±0.20(Predicted)
- color
- White to off-white
- InChI
- InChI=1S/C5H6BNO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3,9-10H,(H,7,8)
- InChIKey
- YUOLAYZNDYRBEZ-UHFFFAOYSA-N
- SMILES
- B(C1C=CC(=O)NC=1)(O)O
Safety
- RIDADR
- 2811
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- 30492
- Product name
- 6-Hydroxypyridin-3-ylboronic Acid
- Packaging
- 100mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 30492
- Product name
- 6-Hydroxypyridin-3-ylboronic Acid
- Packaging
- 500mg
- Price
- $239
- Updated
- 2024/03/01
- Product number
- 30492
- Product name
- 6-Hydroxypyridin-3-ylboronic Acid
- Packaging
- 250mg
- Price
- $135
- Updated
- 2024/03/01
- Product number
- D449273
- Product name
- 1,6-Dihydro-6-oxopyridine-3-boronicacid
- Packaging
- 250mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- H26341
- Product name
- (6-Hydroxypyridin-3-yl)boronicacid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $70
- Updated
- 2021/12/16
6-HYDROXY-3-PYRIDINEBORONIC ACID Chemical Properties,Usage,Production
Uses
6-Hydroxypyridin-3-ylboronic acid is a heterocyclic building block, which can be used in the synthesis of non-nucleoside inhibitors of hepatitis C virus (HCV) RNA-dependent RNA polymerase nonstructural protein 5B (NS5B). 6-Hydroxypyridin-3-ylboronic acid has also been used in the synthesis of mammalian target of rapamycin (mTOR) inhibitors[1][2].
References
[1] Hendricks RT, et al. 3-Hydroxyisoquinolines as inhibitors of HCV NS5b RNA-dependent RNA polymerase. Bioorg Med Chem Lett. 2009 Jan 15;19(2):410-4. DOI:10.1016/j.bmcl.2008.11.060
[2] Verheijen JC, et al. Discovery of 4-morpholino-6-aryl-1H-pyrazolo[3,4-d]pyrimidines as highly potent and selective ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 6-aryl substituent. J Med Chem. 2009 Dec 24;52(24):8010-24. DOI:10.1021/jm9013828
6-HYDROXY-3-PYRIDINEBORONIC ACID Preparation Products And Raw materials
Raw materials
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View Lastest Price from 6-HYDROXY-3-PYRIDINEBORONIC ACID manufacturers
- Product
- 6-HYDROXY-3-PYRIDINEBORONIC ACID 903899-13-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 6-HYDROXY-3-PYRIDINEBORONIC ACID 903899-13-8
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09