(R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE
- Product Name
- (R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE
- CAS No.
- 1004538-33-3
- Chemical Name
- (R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE
- Synonyms
- -1-Boc-3-(Dimethylamino);(R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE;Tert-butyl (R)-3-(dimethylamino)pyrrolidine-1-carboxylate;(R)-tert-butyl 3-(dimethylamino)pyrrolidine-1-carboxylate;(R)-3-DIMETHYLAMINO-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;(3R)-3-(dimethylamino)-1-pyrrolidinecarboxylic acid tert-butyl ester;(3R)-3-(Dimethylamino)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester;3-(Dimethylamino)-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester, (3R)-;1-Pyrrolidinecarboxylicacid, 3-(diMethylaMino)-, 1,1-diMethylethyl ester, (3R)-
- CBNumber
- CB81519279
- Molecular Formula
- C11H22N2O2
- Formula Weight
- 214.3
- MOL File
- 1004538-33-3.mol
(R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE Property
- storage temp.
- 2-8°C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B201898
- Product name
- (R)-1-Boc-3-(dimethylamino)pyrrolidine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- AS113983
- Product name
- (R)-1-Boc-3-(Dimethylamino)pyrrolidine
- Purity
- 97+% ee
- Packaging
- 1g
- Price
- $157
- Updated
- 2021/12/16
- Product number
- AS113983
- Product name
- (R)-1-Boc-3-(Dimethylamino)pyrrolidine
- Purity
- 97+% ee
- Packaging
- 250mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- CCH0001340
- Product name
- (R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $326.55
- Updated
- 2021/12/16
- Product number
- 8044DH
- Product name
- (R)-1-Boc-3-(dimethylamino)pyrrolidine
- Packaging
- 500mg
- Price
- $401
- Updated
- 2021/12/16
(R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE Chemical Properties,Usage,Production
Synthesis
1004538-32-2
1004538-33-3
Step 9-2: Preparation of (R)-1-(tert-butoxycarbonyl)-3-dimethylaminopyrrolidine. 1.25 g of (R)-1-(tert-butoxycarbonyl)-3-dimethylaminopyrrolidine hydrochloride (chemical purity: 99.9 area %) was dissolved in a mixed system of 2.46 g of 23 wt% brine, 5.03 g of toluene, and 738 mg of 30 wt% aqueous sodium hydroxide, and the reaction mixture was stirred thoroughly. After completion of the reaction, liquid-liquid separation was carried out and the organic phase was collected. The organic phase was concentrated under reduced pressure to remove the solvent, followed by vacuum drying to afford 999 mg of (R)-1-Boc-3-(dimethylamino)pyrrolidine as a colorless transparent liquid (chemical purity: 99.5 area %, 95% yield). The structure of the product was confirmed by 1H-NMR (CDCl3): δ (ppm) 1.46 (s, 9H), 1.74 (m, 1H), 2.05 (m, 1H), 2.24 (s, 6H), 2.63 (m, 1H), 3.05 (m, 1H), 3.27 (m, 1H), 3.45-3.69 (m, 2H).
References
[1] Patent: EP2050735, 2009, A1. Location in patent: Page/Page column 21-22
(R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-1-BOC-3-DIMETHYLAMINOPYRROLIDINE Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58