ChemicalBook > CAS DataBase List > 2-METHOXY-2-METHYL-PROPYLAMINE

2-METHOXY-2-METHYL-PROPYLAMINE

Product Name: 2-METHOXY-2-METHYL-PROPYLAMINE
CAS No.: 89282-70-2
Chemical Name: 2-METHOXY-2-METHYL-PROPYLAMINE
Synonyms: CHEMBRDG-BB 4100459;2-METHOXYISOBUTYLAMINE;2-METHOXY-2-METHYL-PROPYLAMINE;2-Methoxy-2-methyl-1-propanamine;2-methoxy-2-methylpropan-1-amine;2-Methoxy-2-methyl-propyl-1-amine;1-Amino-2-methoxy-2-methylpropane;1-Propanamine, 2-methoxy-2-methyl-;2-Methoxy-2-methyl-1-propanamine HCl;2-Methoxy-2-methyl-propylamine, 98 %
CBNumber: CB8172136
Molecular Formula: C5H13NO
Formula Weight: 103.16
MOL File: 89282-70-2.mol

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2-METHOXY-2-METHYL-PROPYLAMINE Property

Boiling point:: 115-125 °C
Density: 0.8677 g/cm3
refractive index: 1.41
pka: 8.88±0.10(Predicted)
InChI: InChI=1S/C5H13NO/c1-5(2,4-6)7-3/h4,6H2,1-3H3
InChIKey: ZSTYQALWKOGXOV-UHFFFAOYSA-N
SMILES: C(N)C(OC)(C)C

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Safety

Hazard Codes: Xi
Risk Statements: 43
Safety Statements: 36/37
RIDADR: 2735
HazardClass: IRRITANT
PackingGroup: Ⅲ

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: M331103
Product name: 2-Methoxy-2-methylpropan-1-amine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: 4739AC
Product name: (2-Methoxy-2-methylpropyl)amine
Packaging: 250mg
Price: $116
Updated: 2021/12/16

Activate Scientific

Product number: AS51125-A
Product name: 2-Methoxy-2-methylpropan-1-amine
Purity: 95+%
Packaging: 1g
Price: $165
Updated: 2021/12/16

Synthonix

Product number: M6043
Product name: 2-Methoxy-2-methylpropylamine
Purity: 97%
Packaging: 1g
Price: $170
Updated: 2021/12/16

Matrix Scientific

Product number: 040360
Product name: (2-Methoxy-2-methylpropyl)amine oxalate
Packaging: 500mg
Price: $315
Updated: 2021/12/16

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2-METHOXY-2-METHYL-PROPYLAMINE Chemical Properties,Usage,Production

Uses

2-Methoxy-2-methylpropan-1-amine is a useful research chemical used in the preparation of diaryl dihydropyrazolo[3,4-c]pyridinones and dihydropyrazolo[3,4-f][1,4]oxazepinones as bicyclic lactam-based cannabinoid-1 receptor antagonists for the treatment of obesity.

Synthesis

19752-21-7

1074-82-4

89282-70-2

Example 3 Synthesis of 2-methoxy-2-methylpropylamine: phthalimide potassium salt (3.70 g, 20 mmol) was added to a solution of 1-bromo-2-methoxy-2-methylpropane (3.34 g, 20 mmol) dissolved in 100 mL of dimethylformamide. The reaction mixture was refluxed with stirring for 4 hours, followed by slow cooling to 25°C. After adding 200 mL of chloroform, the mixture was poured into 500 mL of cold water. The aqueous phase was separated and extracted with two 50 mL chloroform. The combined chloroform extracts were washed sequentially with 100 mL of 0.2 N sodium hydroxide solution and 100 mL of water. After drying, the chloroform was removed under reduced pressure. The residue was dissolved in 100 mL of methanol, hydrazine hydrate (2 g, 40 mmol) was added and heated at reflux for 1 hour. After completion of the reaction, methanol was removed by concentration under reduced pressure. Concentrated hydrochloric acid was added to the residual aqueous solution and heated at reflux for 1 hour. Subsequently, it was concentrated under reduced pressure to remove most of the hydrochloric acid. The pH of the wet residue was adjusted to 14 with sodium hydroxide solution and poured into a separatory funnel containing a saturated potassium carbonate solution. The resulting solution was distilled at atmospheric pressure and the product 2-methoxy-2-methylpropylamine (1.6 g, 78% yield) was collected at 125 °C. The product was characterized by infrared spectroscopy (neat) and the major absorption peaks were located at 3280, 3065, 2960, 2920, 1640, 1430, 1365, 1075 cm?1.

References

[1] Patent: US5210270, 1993, A

2-METHOXY-2-METHYL-PROPYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-METHOXY-2-METHYL-PROPYLAMINE manufacturers

Career Henan Chemical Co

Product: 2-METHOXY-2-METHYL-PROPYLAMINE 89282-70-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg，5kg，100kg
Release date: 2019-08-06

89282-70-2, 2-METHOXY-2-METHYL-PROPYLAMINERelated Search:

5,5-Dimethyloxazolidine-2,4-dione VINCLOZOLIN DIHYDROCYTOCHALASIN B 3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE CYTOCHALASIN A CYTOCHALASIN E LAPPACONITINE HYDROBROMIDE 3-ethyl-5,5-dimethyloxazolidine-2,4-dione Efaroxan CYTOCHALASIN B Fenspiride hydrochloride EFAROXAN HYDROCHLORIDE 3-METHOXYVALINE Dichlozolinate Dichlozoline 2-Methoxy-2-methyl-propylamine OXALATE 2-(4-CHLOROPHENOXY)-2-METHYLPROPANAMIDE (-)-N-(CYCLOPROPYLMETHYL)-4,14-DIMETHOXYMORPHINAN-6-ONE HYDROBROMIDE

2-METHOXYISOBUTYLAMINE

2-METHOXY-2-METHYL-PROPYLAMINE

CHEMBRDG-BB 4100459

2-methoxy-2-methylpropan-1-amine

(2-methoxy-2-methylpropyl)amine(SALTDATA: FREE)

2-Methoxy-2-Methylpropan-1-aMine hydrochloride

2-Methoxy-2-methyl-propylamine, 98 %

2-Methoxy-2-methyl-1-propanamine HCl

2-Methoxy-2-methyl-propyl-1-amine

1-Propanamine, 2-methoxy-2-methyl-

2-Methoxy-2-methyl-1-propanamine

1-Amino-2-methoxy-2-methylpropane

2-Methoxy-2-methylpropylamine - [M6043]

89282-70-2