3-Methoxycinnamic acid
- Product Name
- 3-Methoxycinnamic acid
- CAS No.
- 6099-04-3
- Chemical Name
- 3-Methoxycinnamic acid
- Synonyms
- AKOS B004084;AKOS BBS-00006455;RARECHEM BK HC T256;3-Methoxyciamic acid;M-METHOXYCINNAMIC ACID;3-METHOXYCINNAMIC ACID;O-METHYL-M-CUMARIC ACID;3-Methoxycinnamicacid97%;O-METHYL-M-COUMARIC ACID;3-MethoxycinnamicAcid>
- CBNumber
- CB8172590
- Molecular Formula
- C10H10O3
- Formula Weight
- 178.18
- MOL File
- 6099-04-3.mol
3-Methoxycinnamic acid Property
- Melting point:
- 116-119 °C(lit.)
- Boiling point:
- 250.41°C (rough estimate)
- Density
- 1.1479 (rough estimate)
- refractive index
- 1.5088 (estimate)
- storage temp.
- 2-8°C
- solubility
- almost transparency in Methanol
- form
- powder to crystal
- pka
- pK1:4.376 (25°C)
- color
- White to Almost white
- BRN
- 2209732
- LogP
- 1.362 (est)
- CAS DataBase Reference
- 6099-04-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- M0444
- Product name
- 3-Methoxycinnamic Acid
- Purity
- >99.0%(GC)(T)
- Packaging
- 25g
- Price
- $98
- Updated
- 2025/07/31
- Product number
- M0444
- Product name
- 3-Methoxycinnamic Acid
- Purity
- >99.0%(GC)(T)
- Packaging
- 250g
- Price
- $710
- Updated
- 2025/07/31
- Product number
- M262158
- Product name
- 3-Methoxycinnamic Acid
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 2921-1-X7
- Product name
- 3-Methoxycinnamic acid
- Purity
- 97%
- Packaging
- 10g
- Price
- $24
- Updated
- 2021/12/16
- Product number
- 2921-1-X7
- Product name
- 3-Methoxycinnamic acid
- Purity
- 97%
- Packaging
- 25g
- Price
- $50
- Updated
- 2021/12/16
3-Methoxycinnamic acid Chemical Properties,Usage,Production
Chemical Properties
White to light brown fine crystalline powde
Uses
3-Methoxycinnamic acid is a key intermediate in the synthesis of phosphatidylcholines containing cinnamic acids that exhibits antiproliferative properties against human cancer cell lines.
Definition
ChEBI: 3-Methoxycinnamic acid is a hydroxycinnamic acid.
Synthesis
2398-37-0
79-10-7
6099-04-3
GENERAL METHODS: Lithium tert-butoxide or potassium tert-butoxide (3.0 mmol), water (2.0 mL), and acrylic acid (1.2 mmol) were sequentially added to a Schlenk reaction tube and stirred at room temperature for 10 min under nitrogen atmosphere protection. Subsequently, m-bromoanisole (1.0 mmol) and palladium(II)-imidazole complex 1 (1.0 mol%) were added. The reaction mixture was stirred at 100 °C for 12 hours. After completion of the reaction, it was cooled to room temperature and the pH was adjusted to 1 with 4 M hydrochloric acid, followed by extraction with ethyl acetate. The organic phase was washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the residue was purified by fast column chromatography on silica gel to afford the target product 3-methoxycinnamic acid.
References
[1] New Journal of Chemistry, 2015, vol. 39, # 3, p. 2052 - 2059
[2] Journal of Chemical Research, 2013, vol. 37, # 5, p. 294 - 297
3-Methoxycinnamic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Methoxycinnamic acid manufacturers
- Product
- 3-Methoxycinnamic acid 6099-04-3
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-12-17
- Product
- 3-Methoxycinnamic Acid 6099-04-3
- Price
- US $1.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 50 tons
- Release date
- 2020-01-20