ChemicalBook > CAS DataBase List > 3-Methoxycinnamic acid

3-Methoxycinnamic acid

Product Name: 3-Methoxycinnamic acid
CAS No.: 6099-04-3
Chemical Name: 3-Methoxycinnamic acid
Synonyms: AKOS B004084;AKOS BBS-00006455;RARECHEM BK HC T256;3-Methoxyciamic acid;M-METHOXYCINNAMIC ACID;3-METHOXYCINNAMIC ACID;O-METHYL-M-CUMARIC ACID;3-Methoxycinnamicacid97%;O-METHYL-M-COUMARIC ACID;3-MethoxycinnamicAcid>
CBNumber: CB8172590
Molecular Formula: C10H10O3
Formula Weight: 178.18
MOL File: 6099-04-3.mol

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3-Methoxycinnamic acid Property

Melting point:: 116-119 °C(lit.)
Boiling point:: 250.41°C (rough estimate)
Density: 1.1479 (rough estimate)
refractive index: 1.5088 (estimate)
storage temp.: 2-8°C
solubility: almost transparency in Methanol
form: powder to crystal
pka: pK1:4.376 (25°C)
color: White to Almost white
BRN: 2209732
LogP: 1.362 (est)
CAS DataBase Reference: 6099-04-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 2918999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M0444
Product name: 3-Methoxycinnamic Acid
Purity: >99.0%(GC)(T)
Packaging: 25g
Price: $98
Updated: 2025/07/31

TCI Chemical

Product number: M0444
Product name: 3-Methoxycinnamic Acid
Purity: >99.0%(GC)(T)
Packaging: 250g
Price: $710
Updated: 2025/07/31

TRC

Product number: M262158
Product name: 3-Methoxycinnamic Acid
Packaging: 1g
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2921-1-X7
Product name: 3-Methoxycinnamic acid
Purity: 97%
Packaging: 25g
Price: $50
Updated: 2021/12/16

AK Scientific

Product number: 8624BA
Product name: 3-Methoxycinnamic Acid
Packaging: 1g
Price: $63
Updated: 2021/12/16

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3-Methoxycinnamic acid Chemical Properties,Usage,Production

Chemical Properties

White to light brown fine crystalline powde

Uses

3-Methoxycinnamic acid is a key intermediate in the synthesis of phosphatidylcholines containing cinnamic acids that exhibits antiproliferative properties against human cancer cell lines.

Definition

ChEBI: 3-Methoxycinnamic acid is a hydroxycinnamic acid.

Synthesis

2398-37-0

79-10-7

6099-04-3

GENERAL METHODS: Lithium tert-butoxide or potassium tert-butoxide (3.0 mmol), water (2.0 mL), and acrylic acid (1.2 mmol) were sequentially added to a Schlenk reaction tube and stirred at room temperature for 10 min under nitrogen atmosphere protection. Subsequently, m-bromoanisole (1.0 mmol) and palladium(II)-imidazole complex 1 (1.0 mol%) were added. The reaction mixture was stirred at 100 °C for 12 hours. After completion of the reaction, it was cooled to room temperature and the pH was adjusted to 1 with 4 M hydrochloric acid, followed by extraction with ethyl acetate. The organic phase was washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was removed by concentration under reduced pressure and the residue was purified by fast column chromatography on silica gel to afford the target product 3-methoxycinnamic acid.

References

[1] New Journal of Chemistry, 2015, vol. 39, # 3, p. 2052 - 2059
[2] Journal of Chemical Research, 2013, vol. 37, # 5, p. 294 - 297

3-Methoxycinnamic acid Preparation Products And Raw materials

Raw materials

Pyridine Malonic acid 3-Methoxybenzaldehyde

Preparation Products

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View Lastest Price from 3-Methoxycinnamic acid manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 3-Methoxycinnamic acid 6099-04-3
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-12-17

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Methoxycinnamic Acid 6099-04-3
Price: US $1.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50 tons
Release date: 2020-01-20

6099-04-3, 3-Methoxycinnamic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate trans-Cinnamic acid Folic acid Hyaluronic acid Methyl cinnamate N-BUTYL CINNAMATE alpha-Methylcinnamic acid 4-Hydroxycinnamic acid Ethyl cinnamate Acrylic acid Citric acid Ascoric Acid Octyl 4-methoxycinnamate 3,4,5-Trimethoxycinnamic acid ETHOXYLATED BISPHENOL A DIACRYLATE 3,4-Dimethoxycinnamonitrile IsoaMyl 4-MethoxycinnaMate 4-Methoxycinnamic acid

m-Methoxycinnamic acid,97%,predominantly trans

(2E)-3-(3-methoxyphenyl)prop-2-enoic acid

(E)-3-(3-Methoxyphenyl)propenoic acid

3-Methoxy-trans-cinnamic acid

3-Methoxybenzeneacrylic acid

3-Methoxybenzenepropenoic acid

3-Methoxycinnamic Acid, Predominantly Trans

3-Methoxyciamic acid

O-Methyl-m-coumaric Acid O-Methyl-m-cumaric Acid

3-(3-Methoxyphenyl)acrylic acid, 3-(3-Methoxyphenyl)prop-2-enoic acid

3-Methoxycinnamicacid97%

AKOS B004084

AKOS BBS-00006455

M-METHOXYCINNAMIC ACID

O-METHYL-M-COUMARIC ACID

O-METHYL-M-CUMARIC ACID

RARECHEM BK HC T256

TRANS-3-(3-METHOXYPHENYL)ACRYLIC ACID

TRANS-3-METHOXYCINNAMIC ACID

3-METHOXYCINNAMIC ACID

(2E)-3-(3-METHOXYPHENYL)ACRYLIC ACID

META-METHOXY CINNAMMIC ACID

3-METHOXYCINNAMIC ACID, 97%, PREDOMINANT LY TRANS

3-Methoxycinnamic acid, 98+%

m-Methoxycinnamic acid, predominantly trans, 97%

3-Methoxycinnamic acid 97%

3-Methoxycinnamic acid, predominantly trans, 98+%

(E)-3-(3-Methoxyphenyl)acrylic acid

(E)-3-(3-methoxyphenyl)-2-propenoate

3-MethoxycinnamicAcid&gt

2-Propenoic acid, 3-(3-methoxyphenyl)-

benzyl N-[1-[4-[4-[[2-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-2H-quinolin-1-yl]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-2,5-dioxopyrrolidin-3-yl]carbamate

6099-04-3

1533-74-8

6099-4-3

099-04-3

1533748

4036-09-9

6099-69-3

CH3OC6H4CHCHCO2H

Building Blocks

Carbonyl Compounds

Carboxylic Acids

C10

Organic Building Blocks

CARBOXYLIC ACID

Building Blocks

C10

Carbonyl Compounds

Carboxylic Acids

Chemical Synthesis

Organic Building Blocks

Acids & Esters

Anisoles, Alkyloxy Compounds & Phenylacetates

Aromatic Cinnamic Acids, Esters and Derivatives

Cinnamic acid