(R)-3-Amino-1-benzylpiperidine
- Product Name
- (R)-3-Amino-1-benzylpiperidine
- CAS No.
- 168466-84-0
- Chemical Name
- (R)-3-Amino-1-benzylpiperidine
- Synonyms
- C-3101R;CAS:168466-84-0;Linagliptin Impurity 89;(R)-1-benzylpiperidin-3-amine;(R)-1-BENZYL-3-AMINOPIPERIDINE;(R)-3-AMINO-1-BENZYL-PIPERIDINE;(r)-n-benzyl-3-amino-piperidine;1-BENZYL-PIPERIDIN-(R)-3-YLAMINE;(R)-1-BENZYL-PIPERIDIN-3-YLAMINE;(3R)-1-(Benzyl)-3-piperidinaMine
- CBNumber
- CB8175940
- Molecular Formula
- C12H18N2
- Formula Weight
- 190.28
- MOL File
- 168466-84-0.mol
(R)-3-Amino-1-benzylpiperidine Property
- Boiling point:
- 281.2±33.0 °C(Predicted)
- Density
- 1.037±0.06 g/cm3(Predicted)
- Flash point:
- 113℃
- storage temp.
- 2-8°C(protect from light)
- form
- solid
- pka
- 10.21±0.20(Predicted)
- color
- Yellow
- Water Solubility
- Slightly soluble in water.
- CAS DataBase Reference
- 168466-84-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,T
- Risk Statements
- 25-36/37/38
- Safety Statements
- 45-37-26
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- A618623
- Product name
- (R)-3-Amino-1-benzylpiperidine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR15666
- Product name
- (3R)-1-Benzylpiperidin-3-amine
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- 4H30-1-U6
- Product name
- (R)-3-Amino-1-benzylpiperidine
- Packaging
- 1g
- Price
- $44
- Updated
- 2021/12/16
- Product number
- JK197623
- Product name
- (R)-1-Benzyl-3-aminopiperidine
- Purity
- 98%
- Packaging
- 1g
- Price
- $56
- Updated
- 2021/12/16
- Product number
- FA155125
- Product name
- (R)-3-Amino-1-benzylpiperidine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
(R)-3-Amino-1-benzylpiperidine Chemical Properties,Usage,Production
Chemical Properties
White powder or yellow liquid
Uses
(R)-3-Amino-1-benzylpiperidine is used as an organic chemical synthesis intermediate.
Synthesis
168466-80-6
168466-84-0
Example 33: Preparation of (R)-1-benzyl-3-aminopiperidine (R)-1-benzylpiperidinamide (1.1 g) described in Example 2 was used as a starting material, which was mixed with water (5 mL), 30% aqueous sodium hydroxide (6.7 g, 10 eq.), tetrahydrofuran (THF, 10 mL), and an aqueous sodium hypochlorite solution (11.2 g, 1.5 eq.). The reaction mixture was stirred at 15°C for 1 hour, then warmed to 60°C and continued stirring for 2 hours. Upon completion of the reaction, the mixture was cooled to 20 °C and extracted three times with toluene (10 mL). After combining the organic layers, the solvent was removed by concentration under reduced pressure to afford the target product (R)-3-amino-1-benzylpiperidine as a yellow-brown oil (0.8 g, yield: 55%).
References
[1] Patent: US2010/105917, 2010, A1. Location in patent: Page/Page column 21
(R)-3-Amino-1-benzylpiperidine Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-3-Amino-1-benzylpiperidine Suppliers
- Tel
- --
- Fax
- --
- info@abcr.de
- Country
- Germany
- ProdList
- 6831
- Advantage
- 75
View Lastest Price from (R)-3-Amino-1-benzylpiperidine manufacturers
- Product
- (R)-3-Amino-1-benzylpiperidine 168466-84-0
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 375
- Release date
- 2019-09-01